Neurotrophic Factors
Current advances in using neurotrophic factors to treat neurodegenerative disorders
... Neurotrophic factors or neurotrophins are a group of growth factors which have been classically described for their ability to regulate differentiation and to support growth during development of the ...
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Neurotrophic Factors Protect the Intestinal Barrier from Rotavirus Insult in Mice
... infected mice showed no significant changes in permeability compared to uninfected tissue, confirming a previous observation in mice (7). This may be due to the infection- increased expression of GDNF (Fig. 6). GSNO ...
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Inhibition and reversal of growth cone collapse in adult sensory neurons by enteric glia-induced neurotrophic factors
... all neurotrophic factors were neutralized by the ...four neurotrophic factors work together in a synergistic manner or through individual ...multiple neurotrophic factors are ...
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Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements
... of neurotrophic factors produced by their target cells (the neu- rotrophic hypothesis) (Oppenheim, 1991; Lucidi-Phillipi and Gage, 1993; Snider, 1994; Wright et ...such factors are neurotrophins, ...
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Immunohistochemical Localization of Some Neurotrophic Factors and Their Receptors in the Rat Carotid Body
... and neurotrophic factors have been established as signaling molecules played an important role in the development of the ...some neurotrophic factors and their corre- sponding receptors in ...
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The role of regulatory neuropeptides and neurotrophic factors in asthma pathophysiology
... of neurotrophic factors (nerve growth factor, brain-derived neurotrophic factor) in the regulation of bronchial remodeling in asthma has been ...
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Ageing of enteric neurons: oxidative stress, neurotrophic factors and antioxidant enzymes
... that neurotrophic factors may reduce generation of neuronal ...such factors, glial cell line derived neurotrophic factor (GDNF) and neurotrophin-3 (NT-3) have also been found to protect ...
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Original Article Intracranial transplantation of human adipose-derived stem cells promotes the expression of neurotrophic factors and nerve repair in rats of cerebral ischemia-reperfusion injury
... Previous studies have shown ADSCs can differ- entiate into Schwann cell [35] and promote peripheral nerve repair [36, 37]. On the other hand, it has shown that neurotrophic factors are essential molecules ...
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Safety of repeated transplantations of neurotrophic factors-secreting human mesenchymal stromal stem cells
... MSC: Mesenchymal stem cells; NTF: Neurotrophic factors; MSC-NTF cells: Neurotrophic factor-secreting MSC; GDNF: Glial Cell-derived neurotrophic factor; BDNF: Brain-derived neurotrophic f[r] ...
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The effect of 3,4- methylenedioxymethamphetamine on expression of neurotrophic factors in hippocampus of male rats
... MDMA modulates BDNF, NT4, and Trk-β expression in hip- pocampus of rats that received acute treatment.. The effect of 3,4- methylenedioxymethamphetamine on expression of neurotrophic fa[r] ...
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miRNA profiling of NurOwn®: mesenchymal stem cells secreting neurotrophic factors
... survival factors for embryonic, neo- natal, and adult neurons, and have been evaluated in various neurodegenerative disease clinical trials over the past 25 years [6, ...
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Low-intensity pulsed ultrasound promotes Schwann cell viability and proliferation via the GSK-3β/β-catenin signaling pathway
... In both types of peripheral nerve injury, Schwann cells play an important role. After nerve injury, Wallerian degeneration contributes an environment that helps to support the survival of the injured neurons and promote ...
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Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degeneration
... on factors that promote ingrowth and survival of nerves, such as the neurotrophic factors, nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3), along ...
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Stem Cells for Neuro-regeneration: State of the Art
... Human axon growth rates can reach 2 mm/day in small nerves and 5 mm/day in large nerves. The distal segment, however, experiences Wallerian degeneration within hours of the injury; the axons and myelin degenerate, but ...
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STEM CELL THERAPY AS A POTENTIAL TREATMENT FOR GLAUCOMA
... There is potential in stem cell based therapy in treating glaucoma, especially in terms of neuroprotection via secretion of neurotrophic factors. The majority of the studies showed that BDNF expressed by ...
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<p>Update On Cenegermin Eye Drops In The Treatment Of Neurotrophic Keratitis</p>
... release neurotrophic factors, such as nerve growth factor (NGF) and epidermal growth factor, which promote neuronal extension and ...as neurotrophic keratitis or neurotrophic ...severe ...
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Neurotrophic actions of GDNF and neurturin in the developing avian nervous system and cloning and expression of their receptors
... Neurotrophic factors aie molecules involved in the survival and differentiation of neurons during the development of the nervous system (Davies, ...known neurotrophic factors is constantly ...
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<p>Effect of the micro-immunotherapy medicine 2LPARK® on rat primary dopaminergic neurons after 6-OHDA injury: oxidative stress and survival evaluation in an in vitro model of Parkinson’s disease</p>
... of neurotrophic and growth factors, contained in the MIM capsule (see Table 1), were able to protect DAergic neurons from the cell death induced by 6-OHDA and to reduce oxidative ...stress. ...
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Dynamics of neural stem cell mediated neuroprotection in the presence of oxidative stress: studies in vitro and in vivo
... One group of such developmental molecules are neurotrophic factors like, neurotrophic 3,4 & 5 NT-3, 4 & 5, brain derived neurotrophic factor BDNF, glial derived neurotrophic factor GDNF,[r] ...
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Treatment with MOG-DNA vaccines induces CD4+CD25+FoxP3+ regulatory T cells and up-regulates genes with neuroprotective functions in experimental autoimmune encephalomyelitis
... with MOG-DNA (Table 1). A detailed list of differen- tially expressed genes involved in the inflammatory process is provided in Additional file 2. In order to iden- tify the cellular pathways induced by the effect of ...
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