neutralizing antibodies
Genotype specific and cross reactive neutralizing antibodies induced by dengue virus infection: detection of antibodies with different levels of neutralizing activities against homologous and heterologous genotypes of dengue virus type 2 in common marmosets (Callithrix jacchus)
... that antibodies neutralize different genotypes within infecting serotypes, and that the levels were significantly different among different ge- ...of neutralizing activities against different geno- types ...
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Role of Zika Virus Envelope Protein Domain III as a Target of Human Neutralizing Antibodies
... of antibodies (Abs) that target the envelope (E) glycopro- tein of ZIKV, which covers the surface of the ...monoclonal antibodies and polyclonal immune sera isolated from individuals who recovered from ...
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Neutralizing antibodies in Borna disease virus-infected rats.
... partial neutralizing activity and the capacity to precipitate virus after adsorption with ...1), neutralizing antibodies may be di- rected against other viral proteins as ...elicit ...
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Transgenic Mice Secreting Coronavirus Neutralizing Antibodies into the Milk
... virus neutralizing antibodies into their milk during lactation should provide im- mediate protection to piglets against enteric coronavirus infec- ...TGEV neutralizing MAb with a porcine IgA isotype ...
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PERSISTENCE OF NEUTRALIZING ANTIBODIES IN HUMAN SUBJECTS THREE YEARS AFTER ORAL ADMINISTRATION OF A RODENT-ADAPTED STRAIN OF POLIOMYELITIS VIRUS
... THREE YEARS AFTER ORAL ADMINISTRATION OF A RODENT-ADAPTED PERSISTENCE OF NEUTRALIZING ANTIBODIES IN HUMAN SUBJECTS. Services[r] ...
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Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants
... cross-neutralizing antibodies. An ideal MERS vaccine should induce strong neutralizing antibodies against divergent MERS-CoV ...critical neutralizing domain covering residues 377 to ...
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The expanding array of HIV broadly neutralizing antibodies
... such antibodies by ...CDRH3 antibodies are rare in human B cell repertoires posing a challenge for expan- sion upon immunization ...with antibodies of a similar level of affinity maturation (~ 10% ...
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Induction of high-titer neutralizing antibodies, using hybrid human immunodeficiency virus V3-Ty viruslike particles in a clinically relevant adjuvant.
... We describe here the production of hybrid Ty viruslike particles carrying the major neutralizing domain of HIV and demonstrate the induction of high-titer virus-neutralizing antibodies a[r] ...
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Human antibodies that slow erythrocyte invasion potentiate malaria-neutralizing antibodies
... of antibodies elicited by repeated natural infection (Douglas et ...that neutralizing antibodies that target PfRH5 in naturally acquired responses are ...(IgG) antibodies are effec- tive ...
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Neutralizing antibodies against porcine epidemic diarrhea virus block virus attachment and internalization
... PEDV-specific antibodies [28] with some ...Polyclonal antibodies against PEDV were taken as positive control and normal mouse serum was taken as a negative con- ...
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Locking and Blocking the Viral Landscape of an Alphavirus with Neutralizing Antibodies
... The MAb 3B4C-4 Fab fragment complexed with VEEV. The complex of VEEV with 3B4C-4 Fab fragments showed that Fabs bind to their expected epitopes at the tip of domain B on E2 gly- coproteins (Fig. 3b and 4b). The ...
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Role of Human Immunodeficiency Virus Type 1 Envelope Structure in the Induction of Broadly Neutralizing Antibodies
... several antibodies were selected, including the VRC01 variant NIH45-46 and ...site antibodies (HAADs) that expose the coreceptor binding site on gp120 and mimic binding of the host receptor CD4 have also ...
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Neutralizing and Non neutralizing Antibodies to Bovine Thyroid Stimulating Hormone and its Subunits
... neutralizing, and nonneutralizing antibodies were demonstrated in the antisera obtained. First, antisera to TSH, TSHb, and TSHa all bound [ 125 I]TSH and [ 125 I]TSHb. Anti-bTSHb antisera bound [ 125 ...
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Tat-Neutralizing Antibodies in Vaccinated Macaques
... tralization in a broad panel of Tat bioassays. However, for neutralization of Tat uptake and viral transactivation, it was sufficient to have antibodies against the amino terminus of the Tat protein. Apparently, ...
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Anti-idiotypic antibodies induce neutralizing antibodies to rabies virus glycoprotein.
... 19 have recently presented a functional epitope map for the challenge virus standard CVS strain of rabies virus glycoprotein, which suggests the existence of at least three major antigen[r] ...
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Detection of Hepatitis B Virus (HBV) Genotype E Carried—Even in the Presence of High Titers of Anti HBs Antibodies—by an Argentinean Patient of African Descent Who Had Received Vaccination against HBV
... these neutralizing antibodies: (i) such antibodies might exhibit fluctuating levels and may be undetectable at certain times (7); (ii) putative anti-HBs antibodies elicited by the D144A mutant ...
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Dissecting the Human Serum Antibody Response to Repeat Dengue Virus Infections.
... type-specific neutralizing antibodies mostly targeted quaternary epitopes expressed on E protein dimers or higher order structures but not recombinant E protein (rE), which is mainly a monomer in ...
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Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Clade B Clinical Isolates Produced in Peripheral Blood Mononuclear Cells
... broadly neutralizing antibodies (bNAbs) against HIV-1 demonstrate extensive breadth and potency against diverse HIV-1 strains and represent a promising approach for the treatment and prevention of HIV-1 ...
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Detection of Rift Valley fever virus antigen by enzyme linked immunosorbent assay
... Since vaccine antigens responsible for stimulation of RVF antibodies may not be detectable during plaque reduction neutralizing antibodies are not the fiirst few days of disease and sinc[r] ...
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Identification of Two Cross-Neutralizing Linear Epitopes within the L1 Major Capsid Protein of Human Papillomaviruses
... We also identified three other type-specific neutralizing an- tibodies for HPV-16 (L4), HPV-31 (A6), and HPV-45 (E30). MAbs HPV31.A6 and HPV45.E30 recognized conformational epitopes, and MAb HPV16.L4 Ab recognized ...
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