Neutrophil apoptosis
Necrostatin-1 enhances the resolution of inflammation by specifically inducing neutrophil apoptosis
... injury. Neutrophil apoptosis is essential for the successful resolution of ...neutrophils apoptosis and overrides powerful anti-apoptosis signaling from survival factors such as GM-CSF and ...
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Pre–B cell colony–enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis
... Constitutive neutrophil apoptosis can be inhib- ited by multiple inflammatory mediators of microbial or host origin, including LPS, IL-1β, TNF-α, GM-CSF, and IL-8 (16, ...phil apoptosis (30) (data ...
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Original Article Efficiency of IL-17a on neutrophil apoptosis and regulatory mechanisms in septic rats
... on neutrophil apoptosis in septic rats and its ...centrifugation. Neutrophil apoptosis was detected by AnnexinV-FITC and PI double ...group, neutrophil apoptosis rate was lower ...
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Application of Western Blot for detection of neutrophil apoptosis-related proteins
... delay neutrophil apoptosis was documented by density of protein ...showed apoptosis of neutrophils ...of neutrophil apoptosis-related proteins, ...
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Original Article Association between glucose-regulated protein and neutrophil apoptosis in severe acute pancreatitis
... the apoptosis rate of neutrophils reduced gradually in rats with sodi- um taurocholate induced ...delayed apoptosis of peripheral PMN and deterioration of inflammation in SAP ...to neutrophil ...
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Interleukin-18 Delays Neutrophil Apoptosis following Alcohol Intoxication and Burn Injury
... undergo apoptosis to maintain homeostasis and resolution of ...in apoptosis of neutrophils is one important mechanism which allows for their prolonged presence and the release of potentially harmful ...
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Increased serum soluble Fas after major trauma is associated with delayed neutrophil apoptosis and development of sepsis
... of neutrophil elastase (PMNE) and levels of interleukin (IL)-6 were quantified by enzyme-linked immunosorbent assay and related to patients ’ Sequential Organ Failure Assessment (SOFA) score and Multiple Organ ...
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on neutrophil apoptosis in rates with acinetobacter baumannii pneumonia
... way while keeping the polypeptide nature sepa- rated by electrophoresis and biological activi- ties. The proteins or polypeptide on the solid phases would work as antigens and induced immune response with the ...
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The role of the MAPK pathway alterations in GM-CSF modulated human neutrophil apoptosis with aging
... We then focused on p42/p44 MAPK proteins which were shown to be activated in PMN following GM-CSF receptor stimulation, as well as by other stimulants [26-30]. It was already demonstrated that p42/p44 MAPK activation ...
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Accelerated neutrophil apoptosis in the acquired immunodeficiency syndrome
... initiate apoptosis, PMNL are programmed to die within 24 h after release from the bone marrow ...PMNL apoptosis may at least in part account for the defects in PMNL function that occur in HIV ...PMNL ...
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Increased neutrophil apoptosis in chronically SIV infected macaques
... by apoptosis and are then recognized and phagocytosed by macrophages ...to apoptosis may explain suscep- tibility to severe and recurrent infections in some pathological situations ...
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EFFECTS OF SERUM AND PROTEIN SYNTHESIS INHIBITORS ON POLYMORPHONUCLEAR NEUTROPHIL APOPTOSIS
... of apoptosis, including cell shrinkage, nuclear chromatin condensation and DNA fragmentation into nucleosome length fragmentsY-15 The process of programmed cell death (PCD) may then allow recognition and ingestion ...
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Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
... of neutrophil lifespan by induction of apoptosis is critical for maintaining an effective host response and preventing excessive ...to apoptosis, with a marked delay in cell death observed under ...
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Direct Effect of Human Immunodeficiency Virus Protease Inhibitors on Neutrophil Function and Apoptosis via Calpain Inhibition
... on neutrophil apoptosis in similar rank ...attenuating neutrophil functions, caused a significant inhibi- tion of apoptosis, while APV had only small effects on neutro- phil functions and on ...
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Review Article Resolution of inflammation in periodontitis: a review
... of neutrophil infiltration. Apoptosis is then induced in the existing neu- ...trophils. Neutrophil apoptosis is central to the resolution of inflammation and influences the features of other ...
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Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthritis
... synovial neutrophil apoptosis from fol- low-up joint aspirations were available for 16 synovial fluid samples from 10 RA patients, 25 samples from 11 of the patients with non-RA persistent synovitis, and 17 ...
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Virus-stimulated neutrophils in the tumor microenvironment enhance T cell-mediated anti-tumor immunity
... and neutrophil apoptosis [42] for immune ...cellular apoptosis but also a marker for activated immune ...N1 neutrophil [24], poly I:C treatment failed to induce neutrophil-mediated ...
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Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils
... induced apoptosis in the presence of survival-prolonging cytokines interleukin-5 and granulocyte-macrophage colony stimulating factor (GM-CSF) in eosinophils and ...eosinophil apoptosis, but antagonized ...
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The RNA binding protein tristetraprolin schedules apoptosis of pathogen engaged neutrophils during bacterial infection
... in independent triplicates. Total RNA was isolated using 1 ml TRIzol Reagent (Life Technologies, Thermo Fisher Scientific) according to the manufacturer’s protocol. Contaminating DNA was removed by diges- tion with 20 U ...
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Application of methods for detection of apoptosis and necrosis of bovine blood neutrophil granulocytes in vitro
... The study was an in vitro analysis of bovine blood neutrophil apoptosis and necrosis based on the de- tection of their morphological and biochemical features. The experiment was carried out in six clinical- ...
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