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Neutrophil migration

Long term impaired neutrophil migration in mice overexpressing human interleukin 8

Long term impaired neutrophil migration in mice overexpressing human interleukin 8

... and neutrophil precursors was normal in all transgenic ...of neutrophil extravasation, plasma exudation or tissue damage in any IL-8 transgenic ...mice. Neutrophil migration into the inflamed ...

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Reduced expression of miR-146a in human bronchial epithelial cells alters neutrophil migration

Reduced expression of miR-146a in human bronchial epithelial cells alters neutrophil migration

... The migration of neutrophils was studied by neutrophil chemotaxis assay and flow ...the neutrophil attracting chemokines IL-8 and CXCL1 showed increased expression in patients with neutrophilic ...

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Neutralization of osteopontin attenuates neutrophil migration in sepsis induced acute lung injury

Neutralization of osteopontin attenuates neutrophil migration in sepsis induced acute lung injury

... for neutrophil migration into the lungs during polymicrobial sepsis in ...with neutrophil and macrophage infiltration in glioblastoma, the most invasive type of brain tumors/glioma ...excessive ...

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Cyclophilin A cooperates with MIP-2 to augment neutrophil migration

Cyclophilin A cooperates with MIP-2 to augment neutrophil migration

... augmented neutrophil migration observed when CypA and MIP-2 are combined requires that the 2 chemoattractants be present concurrently, or whether the same effect could be mediated by sequential ...in ...

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Prevention of Neutrophil Migration Ameliorates Rat Lung Allograft Rejection

Prevention of Neutrophil Migration Ameliorates Rat Lung Allograft Rejection

... whether neutrophil migration, which can contribute to the development of ischemia-reperfusion injury, correlates with lung allograft ...of neutrophil migration may suppress acute lung ...

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Drift-Diffusion Analysis of Neutrophil Migration during Inflammation Resolution in a Zebrafish Model

Drift-Diffusion Analysis of Neutrophil Migration during Inflammation Resolution in a Zebrafish Model

... Mathematical testing of the fit of the two models suggested that the drift-diffusion model fitted better with the data, but we were alert to the possibility that drift-diffusion models might appear superior due to the ...

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Drift-Diffusion Analysis of Neutrophil Migration during Inflammation Resolution in a Zebrafish Model.

Drift-Diffusion Analysis of Neutrophil Migration during Inflammation Resolution in a Zebrafish Model.

... restricted migration away from the site of tissue ...each neutrophil in six individual fish, the distance from the wound was calculated using algorithms within Volocity and plotted against ...

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Cigarette smoke induces β2-integrin-dependent neutrophil migration across human endothelium

Cigarette smoke induces β2-integrin-dependent neutrophil migration across human endothelium

... Cigarette smoke exposure to mice leads to a neutrophil influx in BALF and lung tissue [26]. To investigate the expression of CD11b in vivo , male Balb/C mice were exposed to air or smoke for 5 days and ...

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Remodeling of neutrophil phospholipids with 15(S) hydroxyeicosatetraenoic acid inhibits leukotriene B4 induced neutrophil migration across endothelium

Remodeling of neutrophil phospholipids with 15(S) hydroxyeicosatetraenoic acid inhibits leukotriene B4 induced neutrophil migration across endothelium

... present evidence that remodeling of PMN phospholipids with 15(S)-HETE stereoselectively inhibits PMN migration across endothelium in response to leukotriene B4 (LTB4) and other chemoattractants. Esterified ...

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Doxycycline impairs neutrophil migration to the airspaces of the lung in mice exposed to intratracheal lipopolysaccharide

Doxycycline impairs neutrophil migration to the airspaces of the lung in mice exposed to intratracheal lipopolysaccharide

... The lungs of mice studied 24 h after the administration of intratracheal LPS showed intra-alveolar inflammatory infiltrates (arrows), which were absent in mice that received oral doxycyc[r] ...

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Critical role of endothelial CXCR2 in LPS induced neutrophil migration into the lung

Critical role of endothelial CXCR2 in LPS induced neutrophil migration into the lung

... In models of acute lung injury, CXC chemokine receptor 2 (CXCR2) mediates migration of polymorphonuclear leukocytes (PMNs) into the lung. Since CXCR2 ligands, including CXCL1 and CXCL2/3, are chemotactic for PMNs, ...

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Repelled from the wound, or randomly dispersed? Reverse migration behaviour of neutrophils characterized by dynamic modelling

Repelled from the wound, or randomly dispersed? Reverse migration behaviour of neutrophils characterized by dynamic modelling

... of neutrophil movements during inflammation resolution using a drift– diffusion model of neutrophil migration based on regression analysis ...reverse migration was governed by a stochastic ...

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The interaction between C5a and sphingosine 1 phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation

The interaction between C5a and sphingosine 1 phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation

... C5a-induced neutrophil migration and significantly attenuated C5a-primed neutrophils for ANCA-induced respiratory burst and degranulation, with an inhibition rate of about 80%, which suggests that the S1P ...

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Intestinal P glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis

Intestinal P glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis

... inhibiting neutrophil migration in a Sal- monella infection assay (Supplemental Figure 1; supplemental material available online with this article; ...reduced neutrophil infiltration into the colonic ...

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Repressor and activator protein accelerates hepatic ischemia reperfusion injury by promoting neutrophil inflammatory response

Repressor and activator protein accelerates hepatic ischemia reperfusion injury by promoting neutrophil inflammatory response

... suppressed neutrophil migration in mouse IRI model and decreased primary neutrophils migration activities in response to liver LSEC and ...neutrophils migration and ...

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Decreased CXCR1 and CXCR2 expression on neutrophils in anti neutrophil cytoplasmic autoantibody associated vasculitides potentially increases neutrophil adhesion and impairs migration

Decreased CXCR1 and CXCR2 expression on neutrophils in anti neutrophil cytoplasmic autoantibody associated vasculitides potentially increases neutrophil adhesion and impairs migration

... decreased migration of neutrophils through glomerular endothe- lium after CXCR1 and CXCR2 ...some neutrophil migration through the endothelial monolayer in our in vitro experiments can not completely ...

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Original Article Protective effect of taurine on lipopolysaccharide induced acute lung injury in mice

Original Article Protective effect of taurine on lipopolysaccharide induced acute lung injury in mice

... Abstract: Acute lung injury (ALI), a serious respiratory distress has been associated with considerable human mor- bidity and mortality. Taurine, a physiological semi-essential amino acid has been shown to be ...

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Anti Inflammatory Effects of Statins in Cardiac Surgery Patients

Anti Inflammatory Effects of Statins in Cardiac Surgery Patients

... Clinical outcome data was collected from 90 patients re- cruited as a part of the neutrophil migration study and an additional 61 patients were recruited consecutively who were admitted for planned cardiac ...

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Modeling the pasture-associated severe equine asthma bronchoalveolar lavage fluid proteome identifies molecular events mediating neutrophilic airway inflammation

<p>Modeling the pasture-associated severe equine asthma bronchoalveolar lavage fluid proteome identifies molecular events mediating neutrophilic airway inflammation</p>

... on neutrophil functions in horses with pasture-associated severe equine ...increase neutrophil migration, chemotaxis, cell spreading, transmigration, and in fi ...Increased neutrophil ...

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Repelled from the wound, or randomly dispersed? Reverse migration behaviour of neutrophils characterized by dynamic modelling

Repelled from the wound, or randomly dispersed? Reverse migration behaviour of neutrophils characterized by dynamic modelling

... of neutrophil movements during inflammation resolution using a drift– diffusion model of neutrophil migration based on regression analysis ...reverse migration was governed by a stochastic ...

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