NF-κB p65
Original Article Diosgenin suppressed LPS-induced inflammation through inhibiting HSP90 induced phosphorylation of NF-κb p65
... of NF-κb p65 in HBECs without any affection on the expression of ...of NF-κb ...of NF-κb p65 together with GR ...
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The Expression of SOCS and NF-κB p65 in Hypopharyngeal Carcinoma
... Background: Hypopharyngeal carcinoma is one of the most common types of head and neck tumors. Sup- pressers of cytokine signalling (SOCS) family members are key regulators of cytokine homeostasis, they play important ...
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Original Article MicroRNA-130a overexpression promotes proliferation, migration, and phenotypic modulation of vascular smooth muscle cells via enhancing phosphorylation of NF-κB p65
... phosphorylated NF- κB p65 (p-NF-κB p65) in VSMCs were detected by Western ...p-NF-κB p65 in Ang II-treated ...of NF-κB ...
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Suppression of NF κB/p65 Inhibits the Proliferation in Oral Squamous Cancer Cells
... (NF-κB). NF-κB pathway represents an attractive therapeutic target in both cancer cells and ischemic cells, which involves immune ...of NF-κB target genes in oral squamous cancer ...
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Possible Involvement of Nuclear Factor Kappa B in Rapid Disease Progression in ART Naive HIV 1 Infected Remunerated Blood Donors with History of Oral Iron Intake
... i.e. NF-κB p65 or RelA migrates (translocates) to nucleus on activation where it plays a pivotal role in transactivation of viral genes, including that of HIV-1 [6] ...of NF-κB ...
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Activation of nuclear factor kappa B in peripheral blood mononuclear cells from malaria patients
... elevated NF-κB p65 ac- tivity was observed only on day 7 ...post-treatment. NF-κB activation may be triggered by various ligands or proteins of malaria parasites that induce ...
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Original Article Effects of EphB1 inhibitor on tibia cancer pain in rats and its related mechanism
... and NF-κB p65 path- way in spinal cord, and further promote the for- mation and maintenance of BCP, which has required more experimental researches to con- firm ...
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Original Article Electroacupuncture modulated the inflammatory reaction in MCAO rats via inhibiting the TLR4/NF-κB signaling pathway in microglia
... Abstract: In this study, we aim to investigate the effects of electroacupuncture on the TLR4/NF-κB signaling path- way in microglia. Male Wistar rat of SPF grade (weighing 200±20 g) were randomly divided ...
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Original Article Nuclear factor-κB mediates the phenotype switching of airway smooth muscle cells in a murine asthma model
... ASMCs, NF-κB p65 is intimately involved in the dysfunction of murine ...in NF-κB p65 activity in ASMCs is a surrogate for ...of NF-κB p65 has been observed ...
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The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide- induced acute lung injury in mice
... and NF-kB to further investigate whether GHK-Cu can reduce anti-inflammatory response on the peritoneal ...and NF- κB p65 (Supplementary Figure ...
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Original Article Effect of proteasome inhibitor on NF-κB and MMP-9 expression in synovial tissues of osteoarthritis rats
... activated NF-κB p65 was found in lining cells and inflammatory synovial ...activated NF-κB could facilitate cell prolif- eration, and the release of MMPs and cyto- ...of ...
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The effects of aging on muscle loss and tissue specific levels of NF κB and SIRT6 proteins in rats
... and NF-κB and SIRT6 levels in various ...of NF-κB (p65/RelA) and SIRT6 were measured by Western blot analysis in gastrocnemius, tibialis anterior, quadriceps, soleus, lung, heart, ...
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Original Article Tripartite motif 59 improves atherosclerotic vulnerable plaque stability of ApoE (-/-) mice by regulating the NF-κB signaling pathway
... the NF-κB signaling pathway, and activation of this signal- Figure ...on NF-κB signaling pathway in ApoE (-/-) ...of NF-κB expression in aortic tissue; B: Western blot analysis ...
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MicroRNA-500 sustains nuclear factor- B activation and induces gastric cancer cell proliferation and resistance to apoptosis
... the NF-κB ...the NF-ĸB luciferase activity and the expression levels of numerous NF-ĸB downstream target genes in gastric cancer cells (Figure ...abrogated NF-ĸB activation induced by ...
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Siegesbeckia pubescens Makino inhibits Pam3CSK4-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-κB activation
... of NF-κB/p65 and IκBα, but did not significantly show effect on the proteins involved in MAPKs signaling (p38, ERK and ...by NF-κB-luc reporter gene assay and p65 nuclear ...
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Original Article Toll-like receptor 3 (TLR3) functions as a pivotal target in latent membrane protein 1 (LMP1)-mediated nasopharyngeal carcinoma cell proliferation
... the p65 transcription factor was activated as well as downstream pro-inflammatory gene ...and NF-κB p65-mediated inflammatory responses by po- tentially regulating the TLR3 signal pathway, in ...
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Original Article Osteoblastic NF-κB pathway is involved in 1α, 25(OH)
... factor κB (RANK) for the induction of osteoclastogenesis and the activation of mature osteoclasts [16, ...silenced NF-κB p65 decreased the expression of RANKL in 1α, 25(OH) 2 D 3 -treated ...
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Green tea polyphenol epigallocatechin 3 gallate inhibits advanced glycation end product induced expression of tumor necrosis factor α and matrix metalloproteinase 13 in human chondrocytes
... of NF-κB in advanced glycation end product-BSA-stimulated osteoarthritis chondro- ...and NF-κB translocation were analyzed by western immunoblotting using antibodies specific for the ...
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... were tested for normality using the Kolmogorov Smirnov test and for homogeneity variances prior to further statistical analysis. The data were normally distributed and were expressed as means ± standard error of mean ...
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Decreased SATB1 expression promotes AML cell proliferation through NF-κB activation
... in NF-κB, MAPK and PI3K/Akt signaling pathways, we assessed the protein levels and found that nuclear NF-κB p65 levels were significantly increased in HL-60 SATB1-shRNA cells, while ...
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