NF-κB/p65 protein
Original Article Effects of EphB1 inhibitor on tibia cancer pain in rats and its related mechanism
... of NF-κB p65 in the rat’s spinal dorsal horn of each ...of NF-κB p65 protein ...and NF-κB p65 pathway by inhibiting the binding of EphB1 and its ...
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The effects of aging on muscle loss and tissue specific levels of NF κB and SIRT6 proteins in rats
... ti-p65 NF-κB and 1:750 for ...jurkat protein were analyzed by Western blots for p65-NF-κB and SIRT6 to establish linearity and specificity of the proce- ...of ...
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The Expression of SOCS and NF-κB p65 in Hypopharyngeal Carcinoma
... and protein expression levels of SOCS-1, SOCS-3 and NF-κB p65 in hypopharyngeal carcinoma tissues, para- cancerous tissues and control tissues were detected by RT-PCR and Western blot ...
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The RelB alternative NF-kappaB subunit promotes autophagy in 22Rv1 prostate cancer cells in vitro and affects mouse xenograft tumor growth in vivo
... spectively. NF-κB subunits dimers are retained inactive in the cytoplasm due to the binding with inhibitory pro- teins ...and NF-κB dimers translocate into the nucleus to transactivate their ...
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The Measles Virus V Protein Binds to p65 (RelA) To Suppress NF-κB Activity
... canonical NF- B signaling in epithelial ...suppress NF- B-dependent reporter gene expression in response to activation of the tumor necrosis factor (TNF) receptor, RIG-I-like receptors, or Toll-like ...
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Original Article Deubiquitination and stabilization of IL-33 by USP21
... dual-function protein that acts both as a secreted cytokine and as a nuclear fac- tor regulating gene ...of NF-κB ...The protein stability of IL-33 is maintained by USP21 through deubiquitina- ...
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Original Article Nuclear factor-κB mediates the phenotype switching of airway smooth muscle cells in a murine asthma model
... known, NF-κB, a multiprotein com- plex, is involved in early cellular defense reac- tions in higher organisms and plays a pivotal role in immune and inflammatory responses ...for NF-κB ...
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Original Article NF-κB inhibition rescues Toll-like receptor 9 expression in human papillomavirus type 11 infected HaCaT cells
... upstreams NF-κB signaling [2, ...E7 protein induced loss of TLR9 expres- sion and prevented production of IL-8, IFN, and MIP3α ...with NF-κB inhibitor or siRNA for IKKα or IKKβ and ...
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Anticancer activity of Astragalus polysaccharide in human non-small cell lung cancer cells
... In recent years, APS has been shown to enhance immune function in micro environments [11] and inhibit colon cancer cell growth in vivo [9]. Many studies reported that APS can improve immune functions, but it is unclear ...
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Original Article Stragaloside IV weakens cognitive deficits of septic- associated encephalopathy through oxidative stress, induced nitric oxide synthase and inflammation in a mouse model
... (NF-κB) p65 unit and Tumor necrosis factor alpha (TNF-α) were analyzed by ELISA ...(iNOS) protein expression was measured using western blotting ...GSH-PX, NF-κB p65 unit ...
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Activation of NF-κB by the Kaposi's Sarcoma-Associated Herpesvirus K15 Protein Involves Recruitment of the NF-κB-Inducing Kinase, IκB Kinases, and Phosphorylation of p65
... the NF- B consensus sequence ...strongest NF- B inducer among all KSHV proteins (60). Overexpression of the NF- B-inducing ki- nase, NIK, also increases interaction of NF-B with DNA ...
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Liang-Ge-San, a classic traditional Chinese medicine formula, protects against lipopolysaccharide-induced inflammation through cholinergic anti-inflammatory pathway
... against NF-κB p65, p-IκBα (Ser32) and IκBα were obtained from Cell Signaling Technology (Danvers, ...cytoplasmic protein extraction kit was purchased from Beyotime (Jiangsu, ...BCA ...
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Original Article Therapeutic effects of recombinant human keratinocyte growth factor-2 on hyperoxia-induced bronchopulmonary dysplasia in neonatal rats
... Total protein was quan- titated by the Bio-Rad protein ...total protein (20 μg) were separat- ed by SDS-PAGE and transferred onto PVDF ...1:1000), NF-κB p65 (Cell signaling ...
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Immune response associated with Toll like receptor 4 signaling pathway leads to steroid induced femoral head osteonecrosis
... The protein levels of TLR4, MyD88, NF-κB p65 and MCP-1 were detected by Western ...4°C. Protein of lysates were subsequently dissolved in SDS sample buffer ...
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Curcumin attenuates MSU crystal induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage
... of NF-κB subunit p65 and P50 as well as p65 and p50 protein levels through western ...the protein levels of p-p65 and p-p50 as well as p65 and p50 protein ...
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Herpes Simplex Virus 1 Protein Kinase US3 Hyperphosphorylates p65/RelA and Dampens NF-κB Activation
... Most NF- B dimers are inactively sequestered in the cytoplasm because of their association with IB proteins, the most common of which is I B ␣ ...the NF- B p65/p50 heterodimers, their nuclear ...
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Decreased SATB1 expression promotes AML cell proliferation through NF-κB activation
... in NF-κB, MAPK and PI3K/Akt signaling pathways, we assessed the protein levels and found that nuclear NF-κB p65 levels were significantly increased in HL-60 SATB1-shRNA cells, ...
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Original Article Toll-like receptor 3 (TLR3) functions as a pivotal target in latent membrane protein 1 (LMP1)-mediated nasopharyngeal carcinoma cell proliferation
... the p65 transcription factor was activated as well as downstream pro-inflammatory gene ...and NF-κB p65-mediated inflammatory responses by po- tentially regulating the TLR3 signal pathway, in ...
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Original Article Protective effects of quercetin against myocardial ischemia/reperfusion injury in rats
... of NF-κB pathway triggers the overproduction of pro-inflammatory cyto- kines, such as IL-1β, IL-6 and TNF-α, which are detrimental to the myocardial functions ...Akt, NF-κB p65, Bcl-2 ...
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Original Article Tripartite motif 59 improves atherosclerotic vulnerable plaque stability of ApoE (-/-) mice by regulating the NF-κB signaling pathway
... of NF-κB signal- ing pathway activity, and NF-κB also regulates TRIM protein expression in both directions [22- ...The NF-κB signaling pathway covers multi- ple factors ...
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