Nitric Oxide and Vasodilation
Vasodilation of swimbladder vessels in the european eel (Anguilla anguilla) induced by vasoactive intestinal polypeptide, nitric oxide, adenosine and protons
... of nitric oxide synthase, significantly enhanced the flow-induced increase in perfusion ...a vasodilation, as indicated by a significant decrease in perfusion ...a vasodilation of swimbladder ...
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Nitric oxide contributes to estrogen induced vasodilation of the ovine uterine circulation
... uterine vasodilation after the response to E 2 ...uterine vasodilation partially ...maximum vasodilation has occurred either NOS can- not be completely inhibited, our doses were not high enough, or ...
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Insulin mediated skeletal muscle vasodilation is nitric oxide dependent A novel action of insulin to increase nitric oxide release
... To investigate whether insulin modulates the vascular re- sponse to EDNO, SNP, which acts as exogenous NO donor and directly dilates smooth vascular muscle (endothelium-independent vasod[r] ...
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Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide production
... the vasodilation, but that seemingly the inhibition of the KCNQ-type voltage-gated potassium channels resulted in the most remarkable decrease in the rate of ...
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6-Gingerol alleviates exaggerated vasoconstriction in diabetic rat aorta through direct vasodilation and nitric oxide generation
... vasorelaxant, nitric oxide, advanced glycation end products, vascular complications Introduction Diabetes mellitus (DM) is a common disease that affects almost 387 million people worldwide with a prevalence ...
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Acute blockade of nitric oxide synthase inhibits renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious rats
... There was no significant difference in aortic or renal cGMP content between virgin and pregnant rats in the control condition and after nitric oxide synthase blockade.. oxide synthase in[r] ...
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Is Nitric Oxide a Hormone?
... Evidences for an endocrine role of NO. The first evidence for intravascular NO transport, provided by Cannon III et al. [96] in 2001, showed that inhaled NO can be transported in the blood and results in peripheral ...
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Hypercholesterolemia decreases nitric oxide production by promoting the interaction of caveolin and endothelial nitric oxide synthase
... artery vasodilation associated with high plasma cholesterol is generally observed in the absence of changes in eNOS protein lev- els (6, 37) or structural alterations of the vascular wall (3, ...
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The Roles of Nitric Oxide Synthase/Nitric Oxide Pathway in the Pathology of Vascular Dementia and Related Therapeutic Approaches
... Figure 5. Inflammation leads to VaD pathogenesis by increasing the expression of iNOS. Ischemia, hypoxia, and continuous oxidative stress in the brain can induce inflammation, which can activate the TLR4/NF‐κB pathway to ...
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New nitric oxide donor drugs
... our results we felt we could confidently say that the microvasculature in the finger pulp was not being affected by the exogenous NO being supplied to it. 4.3.6. C o n clu sio n s The finding that SNAG causes significant ...
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Vascular nitric oxide: formation and function
... Nitrovasodilators have long been used in clinical settings to treat angina pectoris. Even though the physiological effects of nitrate administration is undeniably beneficial, the mecha- nisms through which it exerts its ...
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Nitric oxide synthase and the contribution of nitric oxide to vertebrate motor control
... 2003). Nitric oxide has been implicated as a metamodulator of locomotion and may play a part in the development of amphibian motor systems and their maturation (see McLean et ...
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Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides
... histochemical studies of RA synovium with antiserum against iNOS revealed that iNOS protein was strongly expressed in synovial lining cells, endothelial cells, and, to a lesser extent, i[r] ...
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Nitric Oxide-Dependent Penile Erection in Mice Lacking Neuronal Nitric Oxide Synthase
... In cross sections of the proximal penis of the wild-type (A) and nNOS- mouse (B), staining of dorsal penile nerves (arrow) is observed only in the wild-type penis. Counterstaining with h[r] ...
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Hypergravity upregulates renal inducible nitric oxide synthase expression and nitric oxide production
... dysfunction. Nitric oxide (NO), which is endogenously synthesized by inducible NO synthase (iNOS), plays an important role in the regulation of renal ...
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Exhaled nitric oxide and inducible nitric oxide synthase gene polymorphism in Japanese asthmatics
... nitric oxide synthase. 4 In addition, inducible nitric oxide synthase (iNOS) is activated by in flammatory cytokines, and iNOS activity in bronchial epithelial cells is a major determinant of ...
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Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis
... and nitric oxide Mechanisms of osteoarthritis The clinical manifestations of osteoarthritis stem mostly from the changes that occur within articular ...
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Nitric oxide for cancer therapy
... of nitric oxide resulted in cytostatic and cytotoxic activity of target ...of nitric oxide in cancer ...NO: Nitric oxide; PDE: Phosphodiesterase; PKA: Protein kinase A; PKG: ...
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NITRIC OXIDE A UBIQUITOUS BIOMEDIATOR
... Nitric oxide is a free radical, and its omnipresence in all tissues reveals its versatile nature of being involved in all physiological functions. It has been recognized to play key role in many ...
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Nitric oxide and cancer: a review
... Nitric oxide (NO), is a ubiquitous, water soluble, free radical gas, which plays key role in various physiological as well as pathological processes. Over past decades, NO has emerged as a molecule of ...
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