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Nitric Oxide (NO)

NITRIC OXIDE: A NOVEL THERAPEUTIC TARGET

NITRIC OXIDE: A NOVEL THERAPEUTIC TARGET

... impaired nitric oxide (NO) bioavailability is well- recognized in the pathology of endothelial dysfunction or atherosclerosis, respectively, and characterized by a reduced NO biosynthesis, an accelerated ...

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New nitric oxide releasing materials

New nitric oxide releasing materials

... reaction of NO and water. Studies have shown, however, that nitric oxide undergoes no hydrolysis in an aqueous environment. This lack of reaction with water is essential for the use of NO in the body. It ...

260

Inhibition of Japanese encephalitis virus infection by nitric oxide: antiviral effect of nitric oxide on RNA virus replication.

Inhibition of Japanese encephalitis virus infection by nitric oxide: antiviral effect of nitric oxide on RNA virus replication.

... Prior to acquired immunity becoming fully functional, the host’s innate immunity, a preprogrammed, albeit nonspecific first-line defense, can be rapidly mobilized to combat invading microorganisms during the initial ...

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Effect of anticonvulsants on the nitric oxide system

Effect of anticonvulsants on the nitric oxide system

... The effect of phenobarbital, carbamazepine, valproate sodium, depakine, topiramate and lamo- trigine on the content of NO and NO-synthase ac- tivity in white rat brain tissues has been studied. It was established that ...

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Role of nitric oxide in the gastrointestinal tract

Role of nitric oxide in the gastrointestinal tract

... Worldwide osteoarthritis (OA) affects more than 9.6% of men and 18% of women older that 60 years. Treatment for OA often requires chronic use of selective or nonselective nonsteroidal anti- inflammatory drugs (NSAIDs), ...

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Effects of chitosan on nitric oxide production and inducible nitric oxide synthase activity and mRNA expression in weaned piglets

Effects of chitosan on nitric oxide production and inducible nitric oxide synthase activity and mRNA expression in weaned piglets

... on nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) activity and gene expression in vivo or vitro were investigated in weaned ...

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New nitric oxide donor drugs

New nitric oxide donor drugs

... pressure. It is changes in tone of the smallest blood vessels, the resistance vessels, which are responsible for major alterations in blood pressure. Therefore it is preferable to use the smallest possible vessels which ...

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Exploring the Regulation of Inducible Nitric Oxide Synthase and the Effects of Nitric Oxide Production in Endotoxin-induced Uveitis

Exploring the Regulation of Inducible Nitric Oxide Synthase and the Effects of Nitric Oxide Production in Endotoxin-induced Uveitis

... inducible nitric oxide synthase and the effects of nitric oxide production in endotoxin-induced ...in nitric oxide (NO) production and the concomitant decrease in the activity of ...

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Zeolite catalysts for nitric oxide production

Zeolite catalysts for nitric oxide production

... Nitric oxide catalytic tests were performed in the same way as the acid sites, as well as further studies that considered copper leaching, toxicology of HEK 293 cells, NO production from[r] ...

209

Nitric oxide system and diabetic nephropathy

Nitric oxide system and diabetic nephropathy

... Endothelial dysfunction has also been shown to lead to an uncoupling of the vascular endothelial growth factor (VEGF)-nitric oxide axis resulting in enhanced proin- flammatory and proliferative effects of ...

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NITRIC OXIDE: ROLE IN HUMAN BIOLOGY

NITRIC OXIDE: ROLE IN HUMAN BIOLOGY

... Nitric oxide (NO), a free radical, possesses various modulatory effects on biological systems. NO is synthesized from L- arginine by converting it to L-citrulline via nitric oxide synthase ...

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Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta stimulated rat mesangial cells

Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta stimulated rat mesangial cells

... Nitric oxide (NO) plays an important role in immunological reactions as a host defense mechanism against tumor cells and invasive microorganisms, but it may also damage healthy ...

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Vascular nitric oxide: formation and function

Vascular nitric oxide: formation and function

... Abstract: Nitric oxide (NO) is a structurally simple, highly versatile molecule that was originally discovered over 30 years ago as an endothelium-derived relaxing ...

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C-786T (Promoter) Allelic Variants of Nitric Oxide Synthase Gene and Its Association with Nitric Oxide in Preeclampsia

C-786T (Promoter) Allelic Variants of Nitric Oxide Synthase Gene and Its Association with Nitric Oxide in Preeclampsia

... Nitric oxide (NO) plays a major role in vascular homeostasis. Produced in endothelial cells and platelets by endothelial NO synthase (eNOS) 123 , NO mediates vascular dilation, inhibits platelet ...

151

The biosynthesis of nitric oxide from L-arginine. Nitric oxide formation features and its functional role in mitochondria

The biosynthesis of nitric oxide from L-arginine. Nitric oxide formation features and its functional role in mitochondria

... dothelium, nitric oxide diffuses to smooth muscle syncytia, activating sGC in myocytes and nitrosyla- ting target ...with nitric oxide activates the mentioned ...

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Serum Nitric Oxide Level and Endothelial Nitric
Oxide Synthase Gene INTRON4 VNTR Polymorphism in
Essential Hypertension.

Serum Nitric Oxide Level and Endothelial Nitric Oxide Synthase Gene INTRON4 VNTR Polymorphism in Essential Hypertension.

... . Nitric oxide, the one considered to be the main factor involved in endothelial dysfunction, is found to be the main mediator involved in shear ...endothelial nitric oxide synthase gene in ...

162

Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors

Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors

... proinflammatory nitric oxide (NO) and prostaglandins (PG) may contribute to the antiinflammatory properties of nitric oxide synthase (NOS) ...inducible nitric oxide synthase ...

9

Topological control of nitric oxide secretion by tantalum oxide nanodot arrays

Topological control of nitric oxide secretion by tantalum oxide nanodot arrays

... Background: Nitric oxide (NO) plays a very important role in the cardiovascular system as a major secondary mes‑ senger in signaling ...Tantalum Oxide nanodot arrays ranging from 10 to 200 ...

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Is Nitric Oxide a Hormone?

Is Nitric Oxide a Hormone?

... Nitric oxide (NO) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. Recent evidences suggest that NO may act as an endocrine molecule. The aim of this ...

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Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides

Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides

... In this study, we have identified the source of nitric oxide (NO) produced in the human inflammatory joints by analyzing expression of inducible NO synthase. In ex vivo organ cultures, both inflammatory ...

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