NK cells
Liver resident NK cells confer adaptive immunity in skin contact inflammation
... (NK) cells are important components of the innate immune system ...B cells, NK cells efficiently exert their effector functions, classically without the necessity of prior ...
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Potential Role of Interleukin-18 in the Immunopathogenesis of AIDS: Involvement in Fratricidal Killing of NK Cells
... murine NK cells and Th1 T-cell clones (9, 13, ...on NK cells was not measured in these ...human NK cell line, as well as in freshly isolated primary human NK ...these ...
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Accessory-Cell-Mediated Activation of Porcine NK Cells by Toll-Like Receptor 7 (TLR7) and TLR8 Agonists
... innate cells in swine by TLR7 and TLR8 ...porcine NK cells by increasing gamma interferon (IFN- ␥ ) expression and perforin ...porcine NK cells was mediated by accessory cells, ...
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CD56negCD16+NK cells are activated mature NK cells with impaired effector function during HIV 1 infection
... + cells has also been observed in other infectious diseases ...that NK cells might proliferate and die more rapidly than do T cells however this requires fur- ther investigation ...
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IL-6 and IL-8 secreted by tumour cells impair the function of NK cells via the STAT3 pathway in oesophageal squamous cell carcinoma
... tumour cells, fibroblasts, and immune cells [43– ...these cells define the microenvironment of tumour cells and are involved in the growth and metastasis of tumours ...tumour cells have ...
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Accumulation of Cytotoxic CD16+ NK Cells in Simian Immunodeficiency Virus-Infected Lymph Nodes Associated with In Situ Differentiation and Functional Anergy
... ⴚ NK cells in LN of chronically infected macaques. However, NK cells did not appear to be trafficking to LN, as homing markers CD62L and CCR7 did not increase on circulating NK ...
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Original Article Decreased expression of TIGIT in NK cells correlates negatively with disease activity in systemic lupus erythematosus
... (NK) cells are a subset of mono- nuclear cells, distinguished from B and T lym- phocytes by virtue of their large granular mor- phology and belonging to the innate immune system ...[4]. NK ...
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Contribution of NK cells to immunotherapy mediated by PD 1/PD L1 blockade
... NK cells are innate lymphocytes with cytotoxic activity against cancer cells that also orchestrate the immune response by releas- ing cytokines and chemokines ...(20). NK cells ...
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Influence of NK Cells during Epithelial to Mesenchymal Transition in Oral cancer
... of NK cells during EMT and its correlation to invasive properties of ...of NK cells on EMT could be seen which open up new horizon for immunotherapeutic strategies in the coming ...
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NK cells and psoriasis
... with NK cell biology that are associated with psoriasis including IL-12 and ...NK22 cells in ...NK22 cells are not found in peripheral blood but rather in mucosal/tissue sites within the ...NK22 ...
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Natural Born Killers: NK Cells in Cancer Therapy
... Harnessing cells of the immune system to fight various malignancies has been widely explored, with the employment of immunotherapy revolutionizing cancer ...T cells has undergone extensive research and ...
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When NK cells overcome their lack of education
... in NK cell clones, lead- ing to a vast diversity of NK cells present within each ...of NK cells may lack inhibitory receptors specific for self–MHC-I in each ...educates NK ...
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Interleukin-2 from Adaptive T Cells Enhances Natural Killer Cell Activity against Human Cytomegalovirus-Infected Macrophages
... NKG2C-positive NK cells are induced by HCMV infection and has been speculated that they function as memory-like ...NKG2C-positive NK cells are not responsible for the enhanced PBNK activity ...
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The Human Cytomegalovirus Protein UL16 Mediates Increased Resistance to Natural Killer Cell Cytotoxicity through Resistance to Cytolytic Proteins
... against NK- mediated ...by NK cells (5, 8, 38), possibly by the engagement of inhibitory molecules on the NK ...to NK cells, fibroblasts were infected with different laboratory ...
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Human mesenchymal stromal/stem cells acquire immunostimulatory capacity upon cross-talk with natural killer cells and might improve the NK cell function of immunocompromised patients
... from NK-92 cells through unknown mechanisms ...primary NK cells during cell–cell contact as well as through a soluble ...bright NK cell population was superior in IL-12/IL-18-induced ...
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Differential Association of Gene Content Polymorphisms of Killer Cell Immunoglobulin-Like Receptors with Placental Malaria in HIV− and HIV+ Mothers
... T cells is a key marker indicating progression to immuno- compromised status, where the host could be rendered more susceptible to malaria, tuberculosis and other opportunistic infections ...T cells as a ...
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Clearance of HSV 2 from recurrent genital lesions correlates with infiltration of HSV specific cytotoxic T lymphocytes
... of NK cells to recurrent HSV lesions in comparison to normal ...between NK cell functional activity and viral clearance, suggesting that they provide an accessory function for viral ...of NK ...
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Targeting of CXCR3 improves anti-myeloma efficacy of adoptively transferred activated natural killer cells
... Tissue NK cells undergo a marked increase of effector capacity after an activation/priming phase promoted by cytokines, among which IL-15 is central ...addition, NK cell populations with enhanced ...
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NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma
... of NK cells from patients with B-CLL and SLL and observed a selective and marked functional impairment in cells taken from patients with ...on NK cells from patients with ...of ...
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CXCR5-negative natural killer cells ameliorate experimental autoimmune myasthenia gravis by suppressing follicular helper T cells
... + NK could enter in lymph node fol- licles, and exert efficient control of viral replication within lymph nodes ...+ NK cells could more efficiently migrate into B cell zone than the CXCR5 - ...Tfh ...
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