NMR Metabolomics
A diagnostic biomarker profile for fibromyalgia syndrome based on an NMR metabolomics study of selected patients and controls
... untargeted NMR metabolomics study of celiac disease, a multifactorial immune-mediated enteropathy [27], suggested alterations of energy metabolism - a clinical characteristic in FMS - while urine data ...
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Direct Implementation of Intestinal Permeability Test in NMR Metabolomics for Simultaneous Biomarker Discovery—A Feasibility Study in a Preterm Piglet Model
... a NMR-based metabolomics approach for a simultaneous quantification of L/M ratio and biomarker ...H NMR-based metabolomics. Urine L/M ratio measured by 1 H NMR spectroscopy showed high ...
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NMR metabolomics reveals effects of Cryptosporidium infections on host cell metabolome
... Additional file 2: Figure S2. Metabolic pathways detected in cell cultures’ NMR samples. a Data analysed by MetaboAnalyst 3.0, utilising all compounds which displayed some degree of change as a result of ...
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1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma
... H- NMR metabolomic approach [28, 29], we also demon- strated that GlaB treatment increases both intra- and extracellular levels of lactate in GL261 cells, promoting the glycolytic process over the tricarboxylic ...
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The effect of diet on Plasmodium falciparum development revealed by NMR metabolomics and image analysis
... the NMR centre people, especially Marie Phelan for her incredible support setting up the metabolomics experiments and Rudi Grosman for his help setting up my ssh-ing remotely to the NMR ...
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Overexpression of ORCA3 and G10H in Catharanthus roseus plants regulated alkaloid biosynthesis and metabolism revealed by NMR-metabolomics
... literature NMR profiling data [39,43,50] and the in-house database with more than 500 common metabolites (Table S1). In 1 H-NMR spectrum of both GO and control lines, signals in the aliphatic area (d 0.4 to ...
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Using NMR-based metabolomics to evaluate postprandial urinary responses following consumption of minimally processed wheat bran or wheat aleurone by men and women
... used NMR metabolomics to evaluate urine samples from baseline at one and two hours postprandially, following the consumption of minimally processed bran, aleurone or control by 14 participants (7 Females; 7 ...
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NMR-based metabolomics in wine quality control and authentication
... using NMR metabolomics, with wines produced in 2006 having higher levels of leucine, phenylalanine, citrate, malate, and phenolics, compared to wines that were produced in 2007, and possessed higher levels ...
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NMR-based metabolomics to identify bioactive compounds in herbs and fruits
... by metabolomics. Metabolomics is an approach aimed for the monitoring of primary and secondary metabolism and can be defined as a metabolic snapshot of a living ...in metabolomics e.g., for metabolic ...
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Metabolomics Based Study of the Antileishmanial Activity of Xanthium strumarium Leaf Extract on Promastigotes Phases of Leishmania major by Proton NMR Spectroscopy
... Accepted 20 Jul 2018 Abstract Background: Xanthium strumarium L. is extensively used as a traditional herb to treat many diseases and is also known as a source of phytochemicals. It has been used traditionally to treat ...
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Urinary metabolomics study on the protective role of Orthosiphon stamineus in Streptozotocin induced diabetes mellitus in rats via 1H NMR spectroscopy
... In order to identify the most significantly affected metabolites or the biomarkers of diabetes by the OSAE treatment, metabolite regions were ranked based on the variable importance in projection (VIP) values as given by ...
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Original Article Dynamic metabolites profile of cerebral ischemia/reperfusion revealed by 1H NMR-based metabolomics contributes to potential biomarkers
... Spectra were processed using the proprietary software package AMIX (Bruker Analytik, Rheinstetten, Germany). This divides the spec- trum into a specified number of regions, and integrates the total signal area within ...
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The 1H NMR serum metabolomics response to a two meal challenge: a cross-over dietary intervention study in healthy human volunteers
... Limitations of this study include that the study design did not allow us to investigate specificity of metabolic responses to the included foods, which is necessary for biomarker discovery and validation, or long-term ...
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Data Normalization in NMR-based Metabolomics
... Abstract: The aim of this article is to summarize recent bioinformatic and statistical developments applicable to NMR-based metabolomics. Extracting relevant information from large multivariate datasets by ...
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Metabolomics in Medicine
... in metabolomics. Dr. Maren Laughlen co-director of the new NIH Metabolomics Initiative, states "we hope that many diseases will have metabolic fingerprints that we can ...and metabolomics to sift ...
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Characterization of Cold Stun Syndrome in North Carolina Sea Turtles Using NMR-Based Metabolomics and Random Forest Modeling.
... before and after each sample cohort. These blank samples did not contain PG, eliminating the NMR spectrometer’s microcoil as a source of PG. Additionally, we filtered, lyophilized, and analyzed a sample of the ...
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Classification of Raw Stingless Bee Honeys by Bee Species Origins using NMR-LCMS-based Metabolomics Approach
... the foraged nectar. According to Kek et al., [34], the composition of honey is probably affected by the type of bee because honey-making process is highly related to enzymes added by the bees. Therefore, bee species ...
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Rice Metabolomics
... Changes in the concentrations of the metabolites according to the developmental or diurnal periods were also investigated using metabolomic techniques. The combination of GC–MS and statistical analyses was exploited to ...
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COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access
... of metabolomics data and metadata (Salek et ...as metabolomics results reporting considering publishing ...of metabolomics resources and databases, to ensure connectivity between similar studies and ...
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based metabolomics approach
... (HR-MAS) NMR to investigate the influences of the circadian clock on the metabolic rhythm of the eighteen biomarkers for the larger rosette surface area ...
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