non-alcoholic steatohepatitis
Hepatocellular carcinoma and non-alcoholic steatohepatitis: the state of play
... promote non-alcoholic fatty liver disease (NAFLD), that can lead to the inflammatory form non-alcoholic steatohepatitis (NASH), and can in turn promote ...
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Investigation into the antioxidant role of arginine in the treatment and the protection for intralipid-induced non-alcoholic steatohepatitis
... (NOS). Some NOS isoforms (endothelial NOS (eNOS) and neuronal) are Ca dependent-constitutively expressed and Ca-independent inducible NOS (iNOS) isoform [2, 3]. Arg and its product NO possess potent antistress activity ...
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Effects of Aerobic Exercise on the Intramuscular Lipid and Glycogen Content of Fiber Types in Soleus Muscles of Non Alcoholic Steatohepatitis Model Rats
... Nonalcoholic fatty liver disease (NAFLD) was characterized as a cause of potentially progressive liver damage, and was associated with metabolic disease. A severe form with features of fibrosis was defined as ...
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Methionine and Choline Deficient Diet-induced Non-Alcoholic Steatohepatitis in Rats: Role of Melatonin
... Material and Methods: To achieve this aim, rats were fed MCD diet for 8 weeks to induce non-alcoholic steatohepatitis. Oral administration of MLN (10 mg/kg/day) was done for the last two consecutive ...
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The role of Ursodeoxycholic acid in non-alcoholic steatohepatitis: a systematic review
... We searched a combinatory database of MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, the Chinese Biomedicine Web Base and Chinese scientific journals’ databases for articles published from January ...
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Olmesartan for non alcoholic steatohepatitis complicated with hypertension: An open label study
... Aim: We evaluated the long-term effects of olmesar- tan, an angiotensin type 1 receptor blocker, in pa- tients with non-alcoholic steatohepatitis (NASH) com- plicated with hypertension. Methods: All ...
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Clinical, epidemiological, and laboratory analysis of patients with non alcoholic steatohepatitis
... alone, non-alcoholic steatohepatitis (NASH), fibrosis and cirrhosis may also occur (Brunt, ...from steatohepatitis and accurate assess the degree of ...
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Deficiency of iNOS-derived NO accelerates lipid accumulation-independent liver fibrosis in non-alcoholic steatohepatitis mouse model
... NASH: Non-alcoholic steatohepatitis; iNOS: inducible nitric oxide synthase; NO: Nitric oxide; HFD: High fat diet; AMPK: AMP-activated protein kinase; PPAR- α : Peroxisome proliferators-activated ...
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The role of adipose tissue in the pathogenesis of non-alcoholic steatohepatitis
... Obesity is a complex condition that occurs when there is abnormal or excessive accumulation of fat in the body. [1] The increased rise in obesity rates have been associated with augmented caloric intake, changes in diet ...
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<p>A Review Of Current And Upcoming Treatment Modalities In Non-Alcoholic Fatty Liver Disease And Non-Alcoholic Steatohepatitis</p>
... Abstract: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the ...West. Non-alcoholic steatohepatitis (NASH) is the progressive form of ...
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Pro-Inflammatory CXCR3 Impairs Mitochondrial Function in Experimental Non-Alcoholic Steatohepatitis
... Chemokines are ubiquitous chemotactic molecules that play major roles in acute and chronic inflammatory conditions (6). CXC chemokines are the largest families, members of which are expressed in acutely inflamed and ...
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The FLS (Fatty liver Shionogi) mouse reveals local expressions of lipocalin-2, CXCL1 and CXCL9 in the liver with non-alcoholic steatohepatitis
... to alcoholic steato- hepatitis, with the presence of macrovesicular steatosis, mixed inflammatory cell infiltration of the lobules, bal- looning degeneration and necrosis of hepatocytes, Mallory body formation, ...
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Aliskiren effect on non-alcoholic steatohepatitis in metabolic syndrome
... The non-radioactive in situ detection of NF-kB in par- affin-embedded liver tissue preparations was performed using the Southwestern Histochemistry method, with digoxigenin labeling and detection kits (Roche ...
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Rapid Development of Non-Alcoholic Steatohepatitis in Psammomys obesus (Israeli Sand Rat)
... However, more recently, 2% dietary cholesterol in the context of high fat, high fructose diet (where the Figure 1. Effects of dietary cholesterol supplementation on P. obesus fed the sta[r] ...
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Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis
... Injury observed using the MCDD dietary model of ste- atohepatitis is reportedly associated with increased intes- tinal permeability and the enhanced presence of endotoxin in the portal blood supply [14,29]. Previous ...
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Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats
... The results of the current study also revealed that SDS treatment reduced the rate of upregulation of Nox2 mRNA expression in the NASH rat model. Nox2 is a membrane-bound enzyme complex. It has been shown to be involved ...
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β-glycosphingolipids ameliorated non-alcoholic steatohepatitis in the <em>Psammomys obesus</em> model
... Abstract: Liver steatosis is a common characteristic of obesity and type 2 diabetes, and fatty liver disease is increasingly recognized as a major health burden. Accumulating evidence suggests that β-glycosphingolipids ...
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Comparative studies on cryptogenic chronic liver disease specially related to non alcoholic steatohepatitis (nash) verses other known causes of liver diseases with features of de compensation A case control study
... with steatohepatitis, we found that group-2 (diseased controls) were more likely to have Jaundice, ascites and gastrointestinal ...the Steatohepatitis cases it was observed that with MELD scores below 6 ...
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Effect of curcumin supplementation on serum expression of select cytokines and chemokines in a female rat model of nonalcoholic steatohepatitis
... Objective: We recently reported that curcumin supplementation in a metabolically (i.e., Western diet [WD]) and chemically (i.e., CCl 4 ) induced female rat model of non-alcoholic steatohepatitis ...
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Young adult obese subjects with and without insulin resistance: what is the role of chronic inflammation and how to weigh it non-invasively?
... is non-alcoholic fatty liver disease (NAFLD) [2], ranging from the "simple" fatty liver (FL) to the more severe ...i.e., non-alcoholic steatohepatitis (NASH), both of them ...
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