Non-canonical Wnt pathway
A Wnt1 regulated Frizzled-1/β-Cateninsignaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection
... inhibits Wnt signaling by preventing Fz-LRP6 complex formation induced by Wnt ...binds Wnt molecules with high affinity [41-43], whereas to block Fzd-2 endogen- ous ligands, we used the CRD of Fzd-2 ...
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Flamingo, a cadherin type receptor involved in the Drosophila planar polarity pathway, can block signaling via the canonical wnt pathway in Xenopus laevis
... the wnt signaling pathway is actual involved (apart from Fz and Dsh ), including the wnt ligand itself (reviewed by Adler and Lee, ...that wnt signaling also regulates these cell movements, ...
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WNT5A transforms intestinal CD8αα+ IELs into an unconventional phenotype with pro-inflammatory features
... after WNT pathway interference were also evaluated. Results: Non-canonical WNT pathway elements represented by FZD5, WNT5A and NFATc1 were remarkably elevated in colitis ...The ...
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WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer
... of WNT ligands to induce these behaviors in Kuramochi ...using WNT CM in our experiments, we also conducted all experiments with recombinant WNT proteins with the results being in parallel with those ...
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REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY IN STEM CELLS DEVELOPMENT AND CARCINOGENESIS
... . Wnt (Wingless int-1) gene was first identified as int-1 gene by activation of mouse mammary tumor virus ...of Wnt signaling pathways were developed in stem cells and cancer development 2, ...
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The non canonical Wnt PCP pathway shapes the mouse caudal neural plate
... that Wnt-PCP signalling organises the apical F-actin throughout the PNP, which together with myosin drives NP folding by apical ...the Wnt-PCP pathway produces cellular rearrangements through ...
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Diepenbruck, Sabine (2017): The potential impact of Wnt5a on differentiation and phenotype of dendritic cells found in renal cell carcinoma. Dissertation, LMU München: Medizinische Fakultät
... in Wnt-signalling associated gene expression ...Other Wnt ligands, however, were not found to be differentially expressed between the myeloid ...the Wnt-ligands, ...dependent Wnt -signalling ...
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Role of Wnt canonical pathway in hematological malignancies
... inhibiting Wnt mediated transcription or by inactivating the target ...carcinomas, Wnt canonical signaling pathway has become the potential therapeutic ...of Wnt signaling is an ...
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Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function
... the non- canonical Wnt signalling pathway, delineating Wnt11/RhoA from Wnt5b ...the non-canonical Wnt signalling pathway to regulate morphogenetic movements during ...
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Metastasis associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis
... (sucrose non fermenting 1)-related protein kinase, known as metastasis-associated kinase (MAK) (Gardner et ...the canonical Wnt pathway and upregulates non-canonical Wnt ...
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Wnt signalling in lung development and diseases
... of canonical Wnt signalling in EMT has been con- firmed in studies using Wnt1 and Lef-1 overexpression ...by Wnt signalling of both canonical and non-canonical ...the ...
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WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling
... activated non-canonical Wnt signaling by promoting phosphorylation of JNK, Erk1/2, and Stat3 significantly as with Wnt5a ...both canonical and non- canonical Wnt ...
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Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone
... with canonical Wnt signaling were affected in early Cdx2 ...a Wnt antagonist at the level of ligand-receptor binding (Kawano and Kypta, 2003), which was also found to facilitate diffusion of ...
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Sulf1 has ligand-dependent effects on canonical and non-canonical Wnt signalling
... of canonical Wnt signalling (Ai et ...a non-canonical Wnt, Wnt11b has been shown to stimulate the canonical ...maternal canonical Wnt signalling) which can be ...
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Identification of putative dental epithelial stem cells in a lizard with life long tooth replacement
... the canonical Wnt ...the non-tooth-forming side of the dental lamina implies that dental stem cells are sequestered from signals that might otherwise induce them to ...
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Nucleophosmin leukemogenic mutant activates Wnt signaling during zebrafish development
... of Wnt signaling has been reported in AML blasts expressing leukemogenic fusion proteins [17, 28, 29] but has not been described, to date, in NPMc+ ...investigated Wnt signaling activation in the OCI-AML3 ...
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Wnt6 activates endoderm in the sea urchin gene regulatory network
... SoxB1 (Kenny et al., 1999). SoxB1 protein is eliminated from the micromere nuclei at the 4th cleavage, and from lower Veg2 progeny by hatched blastula stage, but not from the upper Veg2 progeny of the macromeres until ...
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TWEAK activation of the non-canonical NF- B signaling pathway differentially regulates melanoma and prostate cancer cell invasion
... the canonical and non-canonical NF-κB signaling pathways ...the non-canonical NF-κB ...both non-canonical and canonical NF- κB ...the canonical NF-κB ...
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Activation of Wnt/β-catenin signalling promotes mesenchymal stem cells to repair injured alveolar epithelium induced by lipopolysaccharide in mice
... of Wnt/β-catenin signalling may be involved in the pulmonary ...of Wnt/β-catenin signalling in AT II cells has been linked to the pathogenesis of pul- monary ...
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Regulation of Wnt/β-catenin signaling by posttranslational modifications
... in Wnt signaling remains un- determined and ...in Wnt signaling, a prior study shows that p38 MAPK is activated upon Wnt3a stimulation and is crucial for Wnt3a-induced accumulation of β-catenin through ...
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