non-muscle myosin
The role of non muscle myosin IIA in aggregation and invasion of human MCF 7 breast cancer cells
... of non-muscle myosin IIA (NMIIA) in MCF-7/6 cells inhibits their ...to non-transduced or mock-transduced (MCF-7/6shLUC) ...with non-transduced (B), shLUC transduced (C) and shMYH ...
7
Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non muscle myosin II
... Motile cilia generate constant fluid flow over epithelial tissue, and thereby influence diverse physiological processes. Such functions of ciliated cells depend on the planar polarity of the cilia and on their basal ...
10
Identification of non-muscle myosin heavy chain as a substrate for Cdk5 and tool for drug screening
... a non- muscle myosin heavy chain, type B (NMHC-B) was iden- tified as a Cdk5 ...and non-muscle myosins are composed of two heavy chains and two pairs of light ...to muscle ...
11
Distinct cytoskeleton populations and extensive crosstalk control Ciona notochord tubulogenesis
... and non-muscle myosin II-containing constriction midway along the anteroposterior aspect of each notochord cell during this ...and myosin II activity are required for the constriction and cell ...
11
Thesis
... Cell detachment and rounding via trypsinization is a part of standard tissue culture protocol. However, the complete mechanism of cell rounding by detachment remains unclear. Past research efforts have uncovered various ...
26
A role for actomyosin contractility in Notch signaling
... of non-muscle myosin II in this background. Non-muscle myosin II is a multimeric motor protein complex whose heavy chain is encoded by the Drosophila gene zipper, and regulatory ...
15
Molecular mechanisms of decreased smooth muscle differentiation marker expression after vascular injury
... the non- muscle myosin heavy chain B (NMMHC-B) promoter in transiently transfected cells, suggesting that its presence in the lesion may upregulate ...
10
Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes
... Fig. 5 OIM-induced YAP/TAZ activity in C-MSCs is due to actin cytoskeletal tension caused by Int β 1-ROCK signaling. a – j C-MSCs: C-MSCs cultured with GM for 5 days. OIM-C-MSCs: C-MSCs cultured with OIM for 5 days. a – ...
15
Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling
... phosphorylated myosin light chain (MLC) to the lead- ing edge of the ...GFP-tagged non-phosphorylable (dominant negative) MLC (A3dnMLC; mutations T18A, S19A) in A3 ...or non-muscle ...
13
Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells
... the myosin expression profile in prostate cancer cell lines and found that Myo1b, Myo9b, Myo10, and Myo18a were expressed at higher levels in cells with high metastatic ...each myosin resulted in distinct ...
9
Actomyosin contractility and Discs large contribute to junctional conversion in guiding cell alignment within the Drosophila embryonic epithelium
... that non- muscle Myosin II and the polarity proteins Discs large (Dlg) and Bazooka are enriched along cell interfaces in a complex but reproducible pattern that suggests their involvement in ...
10
The Efficacy of Microcurrent Therapy on Eccentric Contraction Induced Muscle Damage in Rat Fast Twitch Skeletal Muscle
... Over recent decades, microcurrent (MC) therapy, which involves application of a very small electric current to the body, has demonstrated considerable po- tential for treatment of several forms of tissue damage. It has ...
14
Laser spectroscopic studies of actin myosin interaction in activated frog muscle
... the myosin heads in active mucle have their probes orientated at the same angle as in rigor, whilst the remainder are highly disordered with a spectrum similar to that of a resting ...the myosin head in ...
348
Quantifying Regional-Scale Water Storage Using Models and Observations: Application For Drought Assessment In South Carolina
... will continue to function normally as if nothing had ever happened. The second is that the cells are damaged, the repair cells repair the problem and the cell continues once again to operate on a normal level and this ...
65
CArG elements control smooth muscle subtype–specific expression of smooth muscle myosin in vivo
... Multiple CArG elements are required for in vivo transcription of SMC-specific genes. The present studies demonstrate that multiple CArG elements play a key role in regula- tion of SM-MHC in vivo. Results of the present ...
13
The paradoxical patent ductus arteriosus
... the muscle, for instance muscular dystrophies (9), or those that target other organs, such as cancer and immune disorders (10, ...cific muscle inflammation/myositis, mus- cular dystrophies in particular and ...
5
Effect of pH on the rate of myosin head detachment in molluscan catch muscle: are myosin heads involved in the catch state?
... of myosin heads, either at low (pCa>8; catch condition) or at high Ca 2+ concentration (pCa ...to myosin heads remaining sustainably attached to actin ...the myosin head model may not be ...
9
Structures of smooth muscle myosin and heavy meromyosin in the folded, shutdown state
... smooth muscle cells is an essential process that allows effective contractile activity over a wide range of cell ...inactive myosin monomers that have been detected in vitro, in which the long tail has a ...
42
Forelimb muscle architecture and myosin isoform composition in the groundhog (Marmota monax)
... the myosin heavy chain (MHC) isoforms expressed within a muscle fiber directly determine fiber isometric tension, unloaded shortening velocity and power (Reiser et ...to muscle architectural ...
12
Identification and characterisation of a type II myosin in the fission yeast <italic>Schizosaccharomyces pombe</italic>
... as myosin II in higher eukaiyotes, it might be expected that Myo2p would be a component of the actin ring and that deletion would have a sim ilar effect as the deletion of other actin ring components which are ...
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