Non-randomised controlled trial
Randomised, double-blind controlled trial by dose reduction of implanted intrathecal morphine delivery in chronic non-cancer pain
... in the study of 15 patients, it was observed that a high rate of patients withdrew from the research ( fi gure 1). Owing to the large number of withdrawals, a fi rst interim analysis was undertaken just beyond the halfway ...
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Efficacy of cloxacillin versus cefazolin for methicillin-susceptible Staphylococcus aureus bacteraemia (CloCeBa): study protocol for a randomised, controlled, non-inferiority trial
... CloCeBa trial is an open-label, randomised, controlled, non-inferiority trial conducted in academic centres throughout ...be randomised (1:1) to receive either cloxacillin or ...
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A randomised controlled non-inferiority trial of primary care-based facilitated access to an alcohol reduction website (EFAR Spain): the study protocol
... test non-inferiority of facilitation to a web-based BI for risky drinkers delivered by PHCP against face-to-face ...A randomised controlled non- inferiority trial comparing both ...
5
Reasons for non recruitment of eligible patients to a randomised controlled trial of secondary prevention after intracerebral haemorrhage: observational study
... Based on pilot data in an international collaboration [17], 20% of all ICH patients (2% of all strokes) should be potentially eligible for RESTART (although these data were unable to take account of patients’ functional ...
5
Study protocol: a randomised controlled trial testing the effectiveness of ‘Op Volle Kracht’ in Dutch residential care
... the non-MID version, and language is simplified; (2) in the MID version, ado- lescents receive more support from social workers ...the non-MID version in order to adapt to their cognitive ability and to ...
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Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA): study protocol for a randomised controlled trial
... Further chemotherapy will be offered to patients as per current practice. There is currently no evidence from RCTs that adjuvant chemotherapy after surgical resec- tion of CLM improves overall survival [33]. However, ...
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Point-of-care C-reactive protein to assist in primary care management of children with suspected non-serious lower respiratory tract infection: a randomised controlled trial
... In this study, children with low CRP levels were prescribed antibiotics, although children who were judged as severely ill or highly suspected of having pneumonia were excluded, and despite evi- dence that CRP levels ...
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Effect of a sport for health intervention (SmokeFree Sports) on smoking related intentions and cognitions among 9 10 year old primary school children: a controlled trial
... In summary, the results of this study indicate that SFS was effective at changing attitudes towards smoking, and increasing the level of individual self-efficacy to refuse ciga- rettes among girls immediately ...
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A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: A proof of principle pilot study
... There is also in vitro evidence that ZA induces apoptosis in mesothelioma cells [4, 6, 18] and favourably affects the host’s immune response to the tumour [5]. Mouse models of meso- thelioma also suggest that ZA inhibits ...
16
The impact of maintaining serum potassium ≥3 6 mEq/L vs ≥4 5 mEq/L on the incidence of new onset atrial fibrillation in the first 120 hours after isolated elective coronary artery bypass grafting – study protocol for a randomised feasibility trial for the proposed Tight K randomized non inferiority trial
... a randomised controlled pilot trial to assess the feasibility of a proposed randomised non-inferiority trial to investigate the impact of maintaining serum potassium ≥ ...
9
A multi centre, non inferiority, randomised controlled trial to compare a cervical pessary with a cervical cerclage in the prevention of preterm delivery in women with short cervical length and a history of preterm birth – PC study
... EP, MAO, BWJM, DJB, CAN, ES and BK represent the PC study group and were involved in conception and design of the study. LEMK and MDZ are involved in the logistics of the study. MTMF, SWAN, MS, MB, MAB, ABH, BBJH, AAMT, ...
9
Multimodality Treatment of Advanced Non-small Cell Lung Cancer: Where are we with the Evidence?
... static Non-small Cell Lung Cancer (SARON: NCT02417662) randomised controlled trial commenced recruitment in early 2016 and will determine the impact on overall survival of RT (both ...
11
Randomised Ambulatory Management of Primary Pneumothorax (RAMPP): protocol of an open-label, randomised controlled trial
... The primary outcome measure will be total length of stay in hospital to include primary hospital stay and readmissions up to 30 days postrandomisation. Patients remaining in hospital overnight will be classed as 1 day; ...
7
Management of critically ill patients receiving noninvasive and invasive mechanical ventilation in the emergency department
... A multicentre randomised controlled trial of the use of continuous positive airway pressure and non-invasive positive pressure ventilation in the early treatment of patients p[r] ...
11
SOFIE: Surgery for Olecranon Fractures in the Elderly: a randomised controlled trial of operative versus non operative treatment
... Background: Displaced olecranon fractures after a simple fall are common in elderly patients. This patient group often has multiple medical co-morbidities and low functional demands. Standard treatment for these ...
5
Cemented versus non cemented hemiarthroplasty of the hip as a treatment for a displaced femoral neck fracture: design of a randomised controlled trial
... • TUG performed; Giving the fact that at discharge with a cut-off point of over 30 seconds is significantly associated with falls. Less than 24 seconds is consid- ered good functioning and has hardly any chance to fall. ...
5
A randomised controlled demonstration trial of multifaceted nutritional intervention and or probiotics: the healthy mums and babies (HUMBA) trial
... : non-fasting blood and urine specimen for biobank; questionnaires including: New Zealand Food Frequency Questionnaire - Short Form [59], New Zealand Physical Activity Questionnaire [60], Edinburgh Postnatal ...
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Protocol for the ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial: a pragmatic multi centre randomised controlled trial of surgical versus non surgical treatment for proximal fracture of the humerus in adults
... Proximal humeral fractures account for approximately 4 to 5% of all fractures. Their incidence rapidly increases with age, and women are affected over twice as often as men. Similar to other primarily osteoporotic ...
11
Non sedation versus sedation with a daily wake up trial in critically ill patients receiving mechanical ventilation (NONSEDA Trial): study protocol for a randomised controlled trial
... Copenhagen Trial Unit; COPD: chronic obstructive pulmonary disease; CAM-ICU: the confusion assessment method in the ICU; DMSC: Data Monitoring and Safety Committee; eCRF: electronic case record form; ETCO2: ...
11
Clinically relevant subgroups in COPD and asthma
... Other clinical features can be used to identify patients who fall into subgroups that may in fl uence management. For instance, early-onset allergic, exercise-induced asthma (EIA) and ASA phenotypes belong to the Th2-high ...
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