Nonhuman primate
High quality sperm for nonhuman primate ART: Production and assessment
... of nonhuman primates, rhesus and cynomolgus macaques, do not spontaneously capacitate in vitro; rather, chemical activation with dibutryl cyclic AMP and caffeine is ...Because nonhuman primate ...
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Biology of E1-Deleted Adenovirus Vectors in Nonhuman Primate Muscle
... Recent observations indicate that the antigenicity of the transgene product encoded within the adenovirus vector can impact the stability of transgene expression (7, 9, 12, 33, 39). Recombinant proteins expressed from ...
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Antibody facilitation of multiple sclerosis like lesions in a nonhuman primate
... Furthermore, in the presence of encephalitogenic (e.g., disease-inducing) T cells, the fully demyelinated lesion is reconstructed by systemic administration of IgG purified from whole myelin-, or MOG-immunized animals, ...
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Paternal Mitochondrial DNA Transmission During Nonhuman Primate Nuclear Transfer
... two nonhuman primate Macaca mulatta offspring born by NT have mtDNA from three sources: (1) maternal mtDNA from the recipient egg, (2) maternal mtDNA from the egg contributing to the donor blastomere, and ...
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Vaccine Protection against Multidrug Resistant Klebsiella pneumoniae in a Nonhuman Primate Model of Severe Lower Respiratory Tract Infection
... Vaccine Protection against Multidrug Resistant Klebsiella pneumoniae in a Nonhuman Primate Model of Severe Lower Respiratory Tract Infection Vaccine Protection against Multidrug Resistant Klebsiella p[.] ...
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Development of a Novel Nonhuman Primate Model for Rift Valley Fever
... Rift Valley fever (RVF) virus (RVFV) can cause severe human disease characterized by either acute-onset hepatitis, delayed-onset encephalitis, retinitis and blindness, or a hemorrhagic syndrome. The existing ...
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Endometrium and endometriosis tissue mitochondrial energy metabolism in a nonhuman primate model
... a nonhuman primate (NHP) model of spontaneous endometriosis in combination with mito- chondrial respirometry assays, and targeted metabolo- mics to determine metabolic alterations in endometrium and ...
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Characterization of a Novel Simian Immunodeficiency Virus from Guereza Colobus Monkeys (Colobus guereza) in Cameroon: a New Lineage in the Nonhuman Primate Lentivirus Family
... the primate lentiviruses for which full-length genome sequences are available fall into five major lineages, on the basis of com- parisons of their sequences and the functional similarity of their genes ...other ...
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Improvement of the Dengue Virus (DENV) Nonhuman Primate Model via a Reverse Translational Approach Based on Dengue Vaccine Clinical Efficacy Data against DENV-2 and -4
... The nonhuman primate (NHP) model is the most widely recognized tool for assessing the protective activity of dengue vaccine candidates, based on the prevention of postinfection DENV ...
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Exogenous LRRK2G2019S induces parkinsonian-like pathology in a nonhuman primate
... Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease among the elderly. To understand its pathogenesis and to test therapies, animal models that faithfully reproduce key pathological PD ...
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Validation of a pan orthopox real time PCR assay for the detection and quantification of viral genomes from nonhuman primate blood
... Here we present a quantitative real time PCR assay validated for the determination of monkeypox viral GC levels in cynomolgus macaque EDTA whole blood (Table 5). The assay was designed to support the near- real-time ...
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A nonhuman primate model of inherited retinal disease
... a nonhuman primate (NHP) closely mirrors that of the human ...National Primate Research Center with visual impairment and findings from clinical ophthalmic examination, advanced retinal imaging, and ...
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Social learning of vocal structure in a nonhuman primate?
... the nonhuman primates, in the sense that all require social models to acquire func- tionally adequate vocal behavior ...that nonhuman primate calls develop under ...
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Acute Fetal Demise with First Trimester Maternal Infection Resulting from Listeria monocytogenes in a Nonhuman Primate Model
... a nonhuman primate model to map the outcome of infection with ...other nonhuman primates have villous hemochorial placentas and invasive extravillous fetal trophoblasts that actively remodel maternal ...
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Humoral Immunity to Adeno-Associated Virus Type 2 Vectors following Administration to Murine and Nonhuman Primate Muscle
... The nonhuman primates that received AAV-EPO had a 2-log-unit increase of AAV-NAb, which peaked on day 29 and decreased 10-fold over the next year ...to nonhuman primate muscle was studied with ...
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A nonhuman primate model of chikungunya disease
... Chikungunya disease is a severely debilitating, mosquito-borne, viral illness that has reached epidemic proportions in Africa, Asia, and the islands of the Indian Ocean. A mutation enhancing the ability of the ...
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Assessing the nonhuman primate reservoir of Schistosoma mansoni in Africa: a systematic review
... Main text: A systematic search of the literature was performed using PubMed, Web of Science, Google Scholar, the World Health Organization (WHO) library database, World Cat, and ScienceDirect without any language ...
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Transplantation in the nonhuman primate MPTP model of Parkinson’s disease: update and perspectives
... transplanted primate DA neurons extensively migrate, even reaching the contralateral hemi- sphere (Sanchez-Pernaute et ...neurons, primate NSCs show widespread migration throughout the MPTP-lesioned NHP ...
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Transcriptionally Abundant Major Histocompatibility Complex Class I Alleles Are Fundamental to Nonhuman Primate Simian Immunodeficiency Virus-Specific CD8+ T Cell Responses
... The best animal model to evaluate human immunodefi- ciency virus (HIV) vaccine proof-of-concept studies is simian immunodeficiency virus (SIV)-infected nonhuman primates (NHPs). Indeed, the focus on cellular ...
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Disruption of Human TRIM5α Antiviral Activity by Nonhuman Primate Orthologues
... In this work we show that TRIM5 proteins from different primate species interact with each other and can interfere with each other’s function. The CypA domain of TRIMCyp is nec- essary for interference with ...
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