nonsmall cell lung cancers
The association of polymorphisms in miRNAs with nonsmall cell lung cancer in a Han Chinese population
... Recently, many studies have reported the association of miRNA genes and NSCLC. In addition, several studies have been carried out to evaluate the association of SNPs located in miRNA genes with the susceptibility of ...
8
Pulmonary complications of immune checkpoint inhibitors in patients with nonsmall cell lung cancer
... ICI-P is rarely observed (<5%) during cancer treatment with immunotherapies; however, it is the most frequent pulmonary complication observed under ICI, others being ICI-SLG, TB or other infections. It is more often ...
23
Therapeutic options targeting angiogenesis in nonsmall cell lung cancer
... The FGF family includes 22 ligands and five receptors with diverse biological functions, including angiogenesis [16, 17]. FGF receptors (FGFRs) are known to be overexpressed in many cancer types and, in some cases, have ...
13
Tailoring treatment of nonsmall cell lung cancer by tissue type: role of pemetrexed
... With improving technology our comprehension of genomics and proteomics thrives. These disciplines have stimulated the growth of pharmacogenomics, which in turn has strengthened our ability to understand resistance ...
17
Endobronchial ultrasound in the management of nonsmall cell lung cancer
... of cell blocks for immunohistochemistry and molecular studies ...unproven lung cancers and lymph node samples will then often be the only material available ...
9
Is mitochondrial dysfunction a driving mechanism linking COPD to nonsmall cell lung carcinoma?
... of cancers are now known to result from mutations in the metabolic enzymes within the mitochondrion, somatic mutations of the mitochondrial genome are established factors in carcinogenesis ...in lung ...
12
Current and future applications of liquid biopsy in nonsmall cell lung cancer from early to advanced stages
... nonmetastatic cancers (lung, colorectal, ovary, breast, liver, pancreas, oesophagus and stomach) ...III cancers, its sensitivity for stage I cancers was low (43%), with lung and ...
15
A REVIEW: STATUS OF GENETIC MODULATED NONSMALL CELL LUNG CANCER TARGETS AND TREATMENT (CURRENT UPDATES IN DRUGS FOR NON SMALL CELL LUNG CANCER TREATMENT)
... differentiation, cell proliferation, and transcriptional ...several cancers, including melanoma, NSCLC, colorectal cancer, papillary thyroid cancer, and ovarian ...
16
Surgery for nonsmall cell lung cancer
... undergoing lung cancer resection on circulatory ...for cancers infiltrating the ...of lung and SVC resection due to the poor long-term survival ...undergoing lung resection en-bloc with SVC is ...
23
Prognostic significance of <em>CDH13 </em>hypermethylation and mRNA in NSCLC
... of cancers, including nonsmall cell lung cancer ...normal lung tissue, with the pooled odds ratio (OR) from seven studies including 448 NSCLC and 345 normal lung tissue (OR, ...
10
Vorinostat approved in Japan for treatment of cutaneous T-cell lymphomas: status and prospects
... Patients with previously untreated stage IIIB or IV nonsmall cell lung cancer were treated with carboplatin and paclitaxel combined with either vorinostat or a placebo. In 94 evaluable patients, the ...
10
Stratified medicine: drugs meet genetics
... to lung function or COPD risk, and the lack of replication of the findings from these generally small studies in the large genome- wide association studies suggests many of the candidate gene findings are false ...
5
LncRNA GAS5 contributes to lymphatic metastasis in colorectal cancer
... This study was a two-stage, case–control sets including 600 newly diagnosed incident CRC cases and 600 healthy controls in stage I, and 800 newly diagnosed incident CRC cases and 800 healthy controls in stage II, which ...
8
Clinical Reasoning: A 35-year-old woman with acute seizures and behavior change
... The possibility of malignancy was high. Therefore, a full evaluation was performed including a CT of the chest, abdomen, and pelvis, a pelvic ultrasound (positive only for uterine leiomyoma), mammogram, and a full-body ...
6
Maintenance erlotinib in advanced nonsmall cell lung cancer: cost-effectiveness in EGFR wild-type across Europe
... metastatic nonsmall cell lung cancer (NSCLC) has demonstrated significant overall survival and progression-free survival benefits compared with best supportive care plus placebo, irrespective of ...
7
Update on nonsmall cell lung cancer
... in lung cancer carcinogenesis, since histological features of angiogenesis, called ‘‘angiogenic squamous dysplasia’’, are described in epithelial precancerous bronchial lesions, with capillary loops projecting ...
13
Nonsmall cell lung carcinoma: diagnostic difficulties in small biopsies and cytological specimens
... differentiated areas. The threshold for p63 IHC determining SqCC lineage is high; the majority (>80%) of the nuclei need to be strongly positive [15, 17, 18]. However, currently p40 is preferred over p63. p40 + , TTF1 ...
15
Customising chemotherapy in advanced nonsmall cell lung cancer: daily practice and perspectives
... However, the prognosis remains poor, despite these improve- ments, and in patients with advanced NSCLC life expectancy rarely exceeds 1 yr, a statistic that demands further improvement. This improvement is likely to be ...
8
Bevacizumab: the evidence for its clinical potential in the treatment of nonsmall cell lung cancer
... humanized, monoclonal antibody directed against human vascular endothelial growth factor (VEGF), is indicated in the US for first-line treatment of nonsmall cell lung cancer (NSCLC) in combination ...
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fur gene expression as a discriminating marker for small cell and nonsmall cell lung carcinomas
... muscle, lung, and testis. mRNA levels in specimens of human lung tissue without neoplastic lesions were also very ...human lung carcinomas of different histopathological types revealed a highly ...
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