normal human bronchial epithelial cells
Cholesterol-Rich Microdomains as Docking Platforms for Respiratory Syncytial Virus in Normal Human Bronchial Epithelial Cells
... the cells were infected with recombinant RSV containing different combi- nations of envelope ...infected cells by each of the evaluated recombinant viruses, although MBCD at low con- centration had a larger ...
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Secondhand smoke inhibits both Cl- and K+ conductances in normal human bronchial epithelial cells
... To test this hypothesis, we designed a system for in vitro exposure of mature, well-differentiated human bronchial epithelial cells (HBECs) to SHS. SHS (sometimes called environmental tobacco ...
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Ligation of protease activated receptor 1 enhances αv β6 integrin–dependent TGF β activation and promotes acute lung injury
... airway epithelial (normal human bronchial epithelial) cells were obtained commercially from Cambrex, and the TML epithelial reporter cells stably expressing firefly ...
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Regional heterogeneity in response of airway epithelial cells to cigarette smoke
... airway epithelial cells from different sites in the lungs have not been fully ...Methods: Human small airway epithelial cells (SAECs) and normal human bronchial ...
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Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients
... in bronchial epithelial cells derived from COPD subjects, demonstrating that these cells are undergoing EMT ...only normal bronchial epithelial cells responded to ...
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Anti-inflammatory effects of antibacterials on human bronchial epithelial cells
... immune cells, NHBE cells (normal human bronchial epithelial cells) and immortalised respiratory cell lines ...in cells of the immune ...
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Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin 8 gene expression in a human bronchial epithelial cell line
... inducing bronchial epithelial cells to express the gene for IL-8, a cytokine that attracts and activates neutrophils, mediators in respiratory epithelial lining fluid (ELF) of CF individuals ...
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Comparison of paired human nasal and bronchial airway epithelial cell responses to rhinovirus infection and IL-13 treatment
... nasal epithelial cells in the study of lower airway ...of bronchial and nasal cells from COPD patients to LPS and cigarette smoke extract, and concluded that nasal cells could not be ...
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The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer
... using human bronchial epithelial BEAS2B cells and measured lactate and glucose concentrations in culture supernatant after 24 ...CSC-treated cells in vitro raises questions about the ...
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<p>Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells</p>
... The human microvascular endothelial cells HMVEC, NSCLC cell lines A549 (adenocarcinoma), H1650 (adeno- carcinoma), SPCA-1 (adenocarcinoma), and the normal lung bronchial epithelial cell ...
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Mechanism of cigarette smoke condensate-induced acute inflammatory response in human bronchial epithelial cells
... on cells, but principally center around an increase in airway inflam- mation as a result of cigarette ...these cells, CSC induced increases in expression of sever- al cytokines at the mRNA ...ithelial ...
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Mechanical compression attenuates normal human bronchial epithelial wound healing
... for cells that underwent a scrape wound (left) and those that experienced both scrape and 6 hours of mechanical com- pression (right) are shown in ...in cells that underwent mechanical compression and are ...
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Overexpression of lncRNA HOXA11-AS promotes cell epithelial–mesenchymal transition by repressing miR-200b in non-small cell lung cancer
... three human NSCLC cells A549, H1299, 95D and a normal human bronchial epithelial cell 16HBE, the results discovered that lncRNA HOXA11-AS expression levels was higher compared ...
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Stimulatory effect of inflammatory cytokines on alpha 1 antichymotrypsin expression in human lung derived epithelial cells
... lung-derived epithelial cells are capable of synthesizing high levels of alpha ...In normal bronchial epithelial cells, as well as in the HTB55 human adenocarcinoma cell ...
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Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines
... Healthy never-smokers with normal lung function (post-bronchodilator forced expiratory volume (FEV) 1 / forced vital capacity (FVC) >0.7 and FEV 1 >80% of predicted) were recruited and inves- tigated after ...
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MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease
... of human bronchi ...microscopically normal lung areas, carefully dissected from lung parenchyma and plated on collagen-coated culture dishes (10 μg/cm 2 rat type I col- lagen; Sigma) in bronchial ...
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In vitro primary cell culture as a physiologically relevant method for preclinical testing of human oncolytic adenovirus
... prostate cells via restricted replication by a prostate-specific regulatory ...in human nonprostate primary ...virus: bronchial epithelial cells, urothelial cells, vascular ...
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Ectopic expression of a small cell lung cancer transcription factor, INSM1 impairs alveologenesis in lung development
... on normal lung development, we generated a conditional lung- specific INSM1 transgenic mouse ...non-ciliated bronchial epithelial club ...bronchiolar epithelial cells impairs ...
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Accumulation of metals in GOLD4 COPD lungs is associated with decreased CFTR levels
... Cigarette smoking has been firmly established as the major cause of COPD, but approximately one-quarter of American adults continue to smoke, despite aggressive smoking prevention and cessation efforts [28]. On the other ...
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Modulation of airway inflammation in cystic fibrosis In vivo suppression of interleukin 8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor
... (CF) epithelial lining fluid (ELF) can induce human bronchial epithelial cells to express the gene for interleukin 8 (IL-8), an ...
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