Nuclear actin
The Putative Pocket Protein Binding Site of Autographa californica Nucleopolyhedrovirus BV/ODV-C42 Is Required for Virus-Induced Nuclear Actin Polymerization
... in nuclear actin polymerization in baculovirus-infected cells include G-actin, actin-related protein complex 2/3 (Arp2/3) (32), and a viral N-WASP-homologous protein, such as Autographa ...
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Baculovirus AC102 Is a Nucleocapsid Protein That Is Crucial for Nuclear Actin Polymerization and Nucleocapsid Morphogenesis
... host actin cytoskeleton within the cell’s nucleus during infection makes it a powerful cell biological ...of nuclear actin is poorly ...polymerizes actin within the nucleus may reveal funda- ...
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Identification of Six Autographa californica Multicapsid Nucleopolyhedrovirus Early Genes That Mediate Nuclear Localization of G-Actin
... Not only does PE38 stimulate DNA synthesis in plasmid- based assays, but AcMNPV pe38 deletion mutants have been found to be defective in viral DNA synthesis and BV progeny production (D. Theilmann, personal ...
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Autographa californica Multiple Nucleopolyhedrovirus Nucleocapsid Protein BV/ODV-C42 Mediates the Nuclear Entry of P78/83
... the nuclear actin polymerization ...the nuclear relocation process of P78/83 was interrupted either by the failure to receive guidance from the cytoplasm-localized C42 mutant or as a consequence of ...
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Gegenfurtner, Florian (2018): Actin-dependent mechanosensing in endothelial cells: regulatory aspects and targeting potential. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... of actin-binding antibody fragments fused to a nuclear localization sequence (nuclear actin chromobody, nAC, ...other actin binding substances that are distributed throughout the ...
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Identification of a Hydrophobic Domain of HA2 Essential to Morphogenesis of Helicoverpa armigera Nucleopolyhedrovirus
... inner nuclear membrane of AcMNPV-infected cells in the presence of cytochalasin D ...that nuclear actin polymeriza- tion is coordinated with nucleocapsid morphogenesis and membrane-capsid ...
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Nuclear Herpesvirus Capsid Motility Is Not Dependent on F Actin
... find nuclear actin rods in these cells after LatA ...if nuclear actin rods are ...formed nuclear actin rods, especially in cells that formed the round form of actin ...
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Framework to function: mechanosensitive regulators of gene transcription
... cytoplasmic actin in regulating gene expression has been known for more than a decade, more recent investigations have shown that nuclear actin can also regulate gene transcription via its ...
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Gerhold, Christian-Benedikt (2012): Structural biochemistry of actin-related protein 8 within its INO80 chromatin remodeler environment. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... Nuclear actin filaments and nucleosomes can be visualized in nuclei that are placed into germinal vesicles (GV) of Xenopus laevis expressing GFP-UtrCH (green fluorescent protein – Utrophin Calponin ...
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A Role for Nuclear F Actin Induction in Human Cytomegalovirus Nuclear Egress
... the nuclear interior, after which assembled capsids must reach the inner nuclear membrane (INM) for translocation to the cytoplasm (nuclear ...during nuclear egress are unknown. Although an ...
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A Role for Myosin Va in Human Cytomegalovirus Nuclear Egress
... for nuclear myosins in intranuclear move- ments of herpesvirus ...or actin filaments (F-actin) ...a nuclear population of myosin V and with nuclear F-actin ...the nuclear ...
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Nesprin 2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton
... Fig. 3. Loss of nesprins prevents ciliogenesis and causes defects in nuclear morphology, but does not affect apical-basal polarity or nuclear positioning. (A) Immunofluorescence of IMCD3 monolayers ...
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Nuclei migrate through constricted spaces using microtubule motors and actin networks in C elegans hypodermal cells
... for actin participation in P-cell nuclear ...thick actin cables (Figs 4 and 8). Alternatively, a branched actin network at the nuclear surface could help squeeze nuclei into ...branched ...
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Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms
... show nuclear localization of YAP even under the high cell density condition, and that exoge- nous expression of E-cadherin in these cells redistributes YAP from the nucleus to the cytoplasm ...the actin ...
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Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB.
... Considering the abovementioned data, we next examined the significance of ACTN4 dimerisation for its ability to activate MMP-3 gene expression. HEK293T cells were transiently transfected with ACTN4delN, ACTN4delSR1-4 and ...
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Adipocyte specific Repression of PPAR gamma by NCoR Contributes to Scleroderma Skin Fibrosis
... NCoR is a transcriptional coregulatory protein that re- cruits histone deacetylases to DNA promoter regions and functions as a key regulator of nuclear receptors in the downregulation of gene expression [27]. This ...
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Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1
... transcription, nuclear migration, and release and are expected to be effective against a broad spectrum of HIV strains because of the highly conserved nature of viral dependency on actin dynamics for ...
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Distinct Actin and Lipid Binding Sites in Ysc84 Are Required during Early Stages of Yeast Endocytosis
... cells, actin filament formation requires a nucleating activity to facilitate formation of an actin nucleus that then promotes the polymerization ...characterized actin nucleators are the Arp2/3 ...
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Wang, Shuaijun (2019): Evaluation of the actin binding natural compounds Miuraenamide A and Chivosazole A. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... functions, actin has not been pushed as a clinically relevant drug ...overall actin polymerization by the use of small molecular binders has precluded the use of actin targeting natural compounds in ...
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Human monocytes and macrophages differ in their mechanisms of adaptation to hypoxia
... Methods: Isolated human CD14 + monocytes were incubated under normoxia and hypoxia conditions with or without phorbol 12-myristate 13-acetate (PMA) stimulation, respectively. Nuclear and cytosolic fractions were ...
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