Nuclear factor activated T-cells 1
Aberrant Activation of the Interleukin-2 Autocrine Loop through the Nuclear Factor of Activated T Cells by Nonleukemogenic Human T-Cell Leukemia Virus Type 2 but Not by Leukemogenic Type 1 Virus
... Human T-cell leukemia virus type 1 (HTLV-1) but not HTLV-2 is associated with adult T-cell ...the nuclear factor of activated T cells (NFAT) in a human ...
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The role of nuclear factor of activated T cells during phorbol myristate acetate-induced cardiac differentiation of mesenchymal stem cells
... transcription factor myogenic differentiation 1 (MyoD) is an early marker of myogenic differentiation and is known to regulate the expression of MHC ...of cells, such as nerve, liver, and fat ...
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Human T-Cell Lymphotropic Virus Type 1 p12I Expression Increases Cytoplasmic Calcium To Enhance the Activation of Nuclear Factor of Activated T Cells
... Human T-cell lymphotropic virus type 1 (HTLV-1) establishes persistent infection and is associated with lymphoproliferative or neurodegenerative ...target cells, remain ...
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Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signaling
... transcription factor NFAT, leading to its nuclear translocation and the activation of target ...ovary cells stably transformed with an NFAT-luciferase reporter ...was activated by IgG from ...
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HYPOXIA INDUCIBLE FACTOR AND OSMOREGULATORY MOLECULES AFFECT CELL BLEBBING; IMPLICATIONS FOR SENESCENCE AND AGEING PROCESS
... the cells cease to divide and there are several suggested mechanisms for cellular senescence which may ultimately lead to the ageing ...transcription factor for ORE/TonE was identified as TonE-binding ...
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Nuclear factor of activated T-cells, NFATC1, governs FLT3ITD-driven hematopoietic stem cell transformation and a poor prognosis in AML
... respectively, of FCN and F mice (average age of 6 months) were treated with doxorubicin plus cytarabine (5 + 3 days), treated with quizartinib (21 days), or mock treated with vehicle only (Fig. 3c). Mice were sacrificed ...
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Human Herpesvirus 8-Encoded vGPCR Activates Nuclear Factor of Activated T Cells and Collaborates with Human Immunodeficiency Virus Type 1 Tat
... the nuclear export of NF-AT is regulated by GSK-3 (12), a downstream target of Akt ...the nuclear export of NF-AT by phosphorylation ...KSIMM cells were transfected with 100 ng of a NF-B luciferase ...
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Physiological tonicity improves human chondrogenic marker expression through nuclear factor of activated T cells 5 in vitro
... by cells is still poorly ...transcription factor participating in the mammalian hypertonic stress ...IMCD cells, p38 mitogen-activated pro- tein kinase (MAPK) signaling was recently also shown ...
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Investigation of the Role of Nuclear Factor of Activated T Cells (NFAT2) in T Regulatory Cell-induced Immune Suppression in Feline Immunodeficiency Virus Infection.
... CD4 T cell count fall below 50/mm 3 , elevated expression of CD38 on T cells is associated with shorter survival (Giorgi et ...of cells and subsequent expansion followed by activation-induced ...
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Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis
... (Nuclear factor of activated T cells, cytoplasmic 1) through two diff erent signalling ...receptor-associated factor 6) and activates NF-κB, JNK, p38, c-fos and ...is ...
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Calcium sensing stromal interaction molecule 2 upregulates nuclear factor of activated T cells 1 and transforming growth factor β signaling to promote breast cancer metastasis
... stained cells in an area was determined according to the following criteria: (+) refers to the number of positive cells below 25%, (++) refers to 25–49%, and (+++) refers more than ...
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Transcriptional Regulation of BK Virus by Nuclear Factor of Activated T Cells
... Vero cells using Fugene (Roche, Branchburg, NJ). Cells were treated with 2 M ionomycin and 80 ng/ml PMA 48 h posttransfec- ...Biotechnology. Cells were harvested by mechanical scraping and were ...
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Activation of Nuclear Factor of Activated T Cells by Human T-Lymphotropic Virus Type 1 Accessory Protein p12I
... 58). HTLV-1 infection is further associated with tropical spas- tic paraparesis/HTLV-1-associated myelopathy and a variety of other immune-mediated disorders (4, 27, 60). While the diseases linked to the ...
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Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-γ stimulated macrophages
... of T-helper-1 re- sponses, which is associated with the pathogenesis of chronic inflammatory ...AP-1, nuclear factor of activated T cells (NFAT), and ICSBP, to the ...
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Nuclear Wiskott–Aldrich syndrome protein co-regulates T cell factor 1-mediated transcription in T cells
... + T cell samples shared similar features in regard to func- tional groups and intragenic and genic ...the nuclear fraction when compared to the cytosolic frac- ...+ T cells where much less ...
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Significance of glioma associated oncogene homolog 1 (GLI1)expression in claudin low breast cancer and crosstalk with the nuclear factor kappa light chain enhancer of activated B cells (NFκB) pathway
... is activated through a non- canonical pathway in EMT and claudin-low ...claudin-low cells (Figure 7A and Figure S5 in Additional file 1) without stimulation, indicating that NFκB is present in an ...
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Attenuated RANKL induced cytotoxicity by Portulaca oleracea ethanol extract enhances RANKL mediated osteoclastogenesis
... Isolated BMMs were plated on 60-mm dishes at a dens- ity of 1 × 10 6 cells. Following incubation under the stated conditions, each sample was lysed in radioimmunopreci- pitation assay (RIPA) buffer (25 mM ...
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Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway
... Total RNA from muscle tissues was isolated using the RNeasy Mini Kit (Qiagen) according to the manufacturer’s protocol. Complementary DNA (cDNA) templates were obtained via reverse transcription of 2 μg of total RNA ...
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Eggshell membrane hydrolyzates activate NF-κB in vitro: possible implications for in vivo efficacy
... the expression of proinflammatory cytokines in mitogen- challenged human PBMCs provided preliminary data that the hydrolyzates’ effect on NF- κ B would be inhibitory. The data reported here show that ESM hydrolyzates ...
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Cyclosporin A inhibits CD40 ligand expression in T lymphocytes
... activation of protein kinase C and a rise in intracellular calcium concentration. CD40 ligand expression was inhibited by pretreatment of T cells with cyclosporin A. Cyclosporin A analogues inhibited CD40 ...
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