Nuclear lamina
The Nuclear Lamina as a Gene-silencing Hub
... the nuclear lamina will greatly enhance our understanding of developmental gene expression and will provide essential insights into the molecular basis of ...the nuclear lamina has uncovered ...
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Unique and Shared Functions of Nuclear Lamina LEM Domain Proteins in Drosophila
... Drosophila nuclear lamina LEM-D proteins is ...clear lamina and the capacity of remaining LEM-D proteins to functionally compensate for the lost ...
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The involvement of the nuclear lamina in human and rodent spermiogenesis: a systematic review
... (the Lamina-associated polypeptide 2, Emerin, MAN1 do- main) family and Barrier-to-Autointegration Factor (BAF) ...inner nuclear membrane proteins that through their interaction with the nuclear ...
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The oocyte lamin persists as a single major component of the nuclear lamina during embryonic development of the surf clam
... Int 1 DeL BioI J I 267 274 (1990) 267 Origil/al Arlirl, The oocyte lamin persists as a single major component of the nuclear lamina during embryonic development of the surf clam GEORGE DESSEV' and ROB[.] ...
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Human Cytomegalovirus UL50 and UL53 Recruit Viral Protein Kinase UL97, Not Protein Kinase C, for Disruption of Nuclear Lamina and Nuclear Egress in Infected Cells
... during nuclear egress in HCMV-infected cells has not been re- ported ...efficient nuclear egress during infection, and thus deserve the name HCMV ...the nuclear rim and that both UL50 and UL53 are ...
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RASCAL Is a New Human Cytomegalovirus-Encoded Protein That Localizes to the Nuclear Lamina and in Cytoplasmic Vesicles at Late Times Postinfection
... inner nuclear membrane (INM) described in ultrastructural studies and in immunoflu- orescence staining analyses of human- and mouse-CMV-in- fected cells at late times ...the nuclear volume ...the ...
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Characterization and Intracellular Localization of the Epstein-Barr Virus Protein BFLF2: Interactions with BFRF1 and with the Nuclear Lamina
... the nuclear membrane not only upon cotransfection in epithelial cells but also during viral ...the nuclear membrane, similar to those reported to occur during the course of herpesviral replication, and (ii) ...
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Roles of the Nuclear Lamina in Stable Nuclear Association and Assembly of a Herpesviral Transactivator Complex on Viral Immediate Early Genes
... the nuclear periphery by studying cells infected with the HSV-1 mutant virus in1814, which carries a gene encoding a mu- tant VP16 molecule defective for binding to HCF-1 and Oct-1 (43), and its rescued virus ...
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Prelamin A and lamin A appear to be dispensable in the nuclear lamina
... Lamin A and lamin C, both products of Lmna, are key components of the nuclear lamina. In the mouse, a deficiency in both lamin A and lamin C leads to slow growth, muscle weakness, and death by 6 weeks of ...
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Chromatin states and nuclear organization in development — a view from the nuclear lamina
... the nuclear lamina in mouse ESCs ...the nuclear periphery for three developmentally regulated loci, in the absence of transcriptional activation ...the nuclear periphery without increasing ...
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Epstein-Barr Virus BGLF4 Kinase Induces Disassembly of the Nuclear Lamina To Facilitate Virion Production
... the nuclear lamina is important for the protein expression levels of EBV BFRF1/BFLF2 and virion ...the nuclear lamina during EBV replication, GFP-lamin A, GFP-lamin A(S22/390A), or GFP-lamin ...
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Mechanosensing By The Nuclear Lamina: From Embryonic Development To Aging
... the lamina and the nucleoplasm (in ‘3D’) (Dahl et ...the lamina (in ‘~2D’) is relatively hindered; however, interphase phosphorylation of lamin-A/C at multiple residues clearly enhances mobility in either ...
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Critical Stages in Viral Replication - Entry, Gene Regulation and Egress
... of nuclear invaginations in some instances (76), and reduced formation of lipid droplets, glycolipids, and autophagosomes (29, 52, ...the nuclear lamina (10) and was shown to anchor the nucleus ...
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Inactivation of Retinoblastoma Protein Does Not Overcome the Requirement for Human Cytomegalovirus UL97 in Lamina Disruption and Nuclear Egress
... in nuclear egress. An important step in nuclear egress is disruption of the nuclear lamina, which, during HCMV infection, requires UL97 (6, 9, ...the nuclear lamina component ...
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Extragenic Suppression of a Mutation in Herpes Simplex Virus 1 UL34 That Affects Lamina Disruption and Nuclear Egress
... the nuclear membrane and nuclear lamina that are thought to facilitate capsid access to the inner nuclear membrane (INM) and curvature of patches of the INM around the cap- sid during ...in ...
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Epstein-Barr Virus BGLF4 Kinase Induces Premature Chromosome Condensation through Activation of Condensin and Topoisomerase II
... the nuclear lamina and actin fiber rearrangement, may facilitate virus mat- uration during the late phase of virus replication ...as nuclear lamina redistribution and cy- toskeleton ...the ...
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Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes
... to nuclear misshaping, increased size, lobulation and blebbing ...the nuclear lamina and nuclear envelope components, we observe that such irregular nuclei are characterized by abnormalities ...
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PubMedCentral-PMC4887340.pdf
... the nuclear lamina in some ...to nuclear stiffening in response to applied force ...rapid nuclear stiffening, actin cytoskeletal polymerization, and gene activation, though, how emerin ...
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Reorganization of Nuclear Pore Complexes and the Lamina in Late-Stage Parvovirus Infection
... he nuclear lamina is a protein-rich structural scaffold, the main components of which are the dynamic type V interme- diate filament proteins called ...The lamina is con- nected to the cytoskeleton ...
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LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells
... HSCs. LaminA/C is known to be in close contact with large chromatin domains named lamina-associated do- mains ...to nuclear LaminA/C [57]. Consistent with the re- duction in LaminA/C ...
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