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Nuclear-Matrix

Conserved Region CR2 of Epstein-Barr Virus Nuclear Antigen Leader Protein Is a Multifunctional Domain That Mediates Self-Association as well as Nuclear Localization and Nuclear Matrix Association

Conserved Region CR2 of Epstein-Barr Virus Nuclear Antigen Leader Protein Is a Multifunctional Domain That Mediates Self-Association as well as Nuclear Localization and Nuclear Matrix Association

... (EBV) nuclear antigen leader protein (EBNA-LP) contains various numbers of W1W2 repeats and a unique carboxyl-terminal Y1Y2 ...mediating nuclear localization, nuclear matrix association, and ...

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The Cellular DNA Helicase ChlR1 Regulates Chromatin and Nuclear Matrix Attachment of the Human Papillomavirus 16 E2 Protein and High-Copy-Number Viral Genome Establishment

The Cellular DNA Helicase ChlR1 Regulates Chromatin and Nuclear Matrix Attachment of the Human Papillomavirus 16 E2 Protein and High-Copy-Number Viral Genome Establishment

... cell nuclear antigen (PCNA) and the flap endonuclease, Fen1 (35, 36), and is important for replication recovery following DNA damage ...reduced nuclear matrix association of E2 and in its increased ...

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The Hinge of the Human Papillomavirus Type 11 E2 Protein Contains Major Determinants for Nuclear Localization and Nuclear Matrix Association

The Hinge of the Human Papillomavirus Type 11 E2 Protein Contains Major Determinants for Nuclear Localization and Nuclear Matrix Association

... strong nuclear localization, whereas the N or C domain was present in both cytoplasm and ...efficient nuclear localization and nuclear matrix ...

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Localization of Human Cytomegalovirus Structural Proteins to the Nuclear Matrix of Infected Human Fibroblasts

Localization of Human Cytomegalovirus Structural Proteins to the Nuclear Matrix of Infected Human Fibroblasts

... and nuclear egress of ...the nuclear matrix of infected cells in order to define spatial relationships and potential colocaliza- tion of structural proteins late in ...a nuclear compart- ment ...

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Tyrosine kinase-dependent release of an adenovirus preterminal protein complex from the nuclear matrix.

Tyrosine kinase-dependent release of an adenovirus preterminal protein complex from the nuclear matrix.

... Adenovirus (Ad) replicative complexes form at discrete sites on the nuclear matrix (NM) through the interaction of Ad preterminal protein (pTP). The NM is a highly salt-resistant fibrillar network which is ...

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Adenovirus Preterminal Protein Binds to the CAD Enzyme at Active Sites of Viral DNA Replication on the Nuclear Matrix

Adenovirus Preterminal Protein Binds to the CAD Enzyme at Active Sites of Viral DNA Replication on the Nuclear Matrix

... Adenovirus (Ad) replicative complexes form at discrete sites on the nuclear matrix (NM) via an interaction mediated by the precursor of the terminal protein (pTP). The identities of cellular proteins ...

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Identification of Novel T Cell Factor 4 (TCF-4) Binding Sites on the HIV Long Terminal Repeat Which Associate with TCF-4, β-Catenin, and SMAR1 To Repress HIV Transcription

Identification of Novel T Cell Factor 4 (TCF-4) Binding Sites on the HIV Long Terminal Repeat Which Associate with TCF-4, β-Catenin, and SMAR1 To Repress HIV Transcription

... cation in comparison to other CNS cellular targets of HIV, such as microglia and perivascular macrophages. In response to signals that inhibit the Wnt/ ␤ -catenin pathway, astrocytes support a much higher level of HIV ...

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Rapid Separation and Quantification of Iron in Uranium Nuclear Matrix by Capillary Zone Electrophoresis (CZE)

Rapid Separation and Quantification of Iron in Uranium Nuclear Matrix by Capillary Zone Electrophoresis (CZE)

... metal matrix is a difficult task in any high performance separation ...of matrix separation, no uncertainty on analyte recovery and reduction in overall analysis ...

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Nuclear matrix protein Matrin 3 is a regulator of ZAP mediated retroviral restriction

Nuclear matrix protein Matrin 3 is a regulator of ZAP mediated retroviral restriction

... Other nuclear matrix proteins which are also RNA binding proteins involved in RNA metabolism display a commonality as to their effects on ZAP-mediated retroviral restriction, as seen for HNRNPU and SFPQ ...

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Phosphorylation of apoptosis repressor with caspase recruitment domain by protein kinase CK2 contributes to chemotherapy resistance by inhibiting doxorubicin induced apoptosis

Phosphorylation of apoptosis repressor with caspase recruitment domain by protein kinase CK2 contributes to chemotherapy resistance by inhibiting doxorubicin induced apoptosis

... to nuclear matrix with a decrease in the cytosolic fraction in human prostate carcinoma cells under androgens and/or growth factors stimuli [34]; CK2α targets to nuclear matrix in response to ...

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Cardiomyocyte-specific expression of the nuclear matrix protein, CIZ1, stimulates production of mono-nucleated cells with an extended window of proliferation in the postnatal mouse heart

Cardiomyocyte-specific expression of the nuclear matrix protein, CIZ1, stimulates production of mono-nucleated cells with an extended window of proliferation in the postnatal mouse heart

... undergo nuclear division without cytokinesis shortly after birth, so the majority become suspended in a bi-nucleated state in the adult ...extracellular matrix and formation of scar tissue that lacks key ...

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Thermal Conductivity Measurement of Zr ZrO2 Simulated Inert Matrix Nuclear Fuel Pellet

Thermal Conductivity Measurement of Zr ZrO2 Simulated Inert Matrix Nuclear Fuel Pellet

... The measured density of the fabricated simulated fuel pellet was 6.008 ± 0.006 g/cc (94.2% of theoretical den- sity). In spite of a low reaction temperature, a highly dense sample could be obtained. Figure 1 shows the ...

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Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication

Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication

... of nuclear export ...in nuclear export [14, ...the nuclear membrane and/or some cellular proteins involved in the transport could be ...but nuclear import is not fully explained ...host ...

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Neutron Skin Effects in Mirror Energy Differences : The Case of Mg 23 - Na 23

Neutron Skin Effects in Mirror Energy Differences : The Case of Mg 23 - Na 23

... The second approach we follow here is inspired by the recent theoretical work by Bonnard et al. [1], where mirror nuclei consisting on a closed-shell core plus a particle or a hole have been studied. By adopting the ...

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Dissection of the mitotic and nuclear functions of Chromator, a nuclear derived spindle matrix component in Drosophila

Dissection of the mitotic and nuclear functions of Chromator, a nuclear derived spindle matrix component in Drosophila

... microtubule-based mitotic motors. The Ncd (nonclaret disjunctional) motor is a KIN C subtype kinesin and belongs to the kinesin-14 subfamily. It moves unidirectionally towards the minus end of microtubules. Ncd attracts ...

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The Respiratory Syncytial Virus Matrix Protein Possesses a Crm1-Mediated Nuclear Export Mechanism

The Respiratory Syncytial Virus Matrix Protein Possesses a Crm1-Mediated Nuclear Export Mechanism

... export protein (see the introduction), is also known to inhibit virus transcriptase activity, with a similar sequestration of M1 protein away from the vRNP observed in the early stages of influenza virus infection (3). ...

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Mitochondrial Protein in the Nucleus

Mitochondrial Protein in the Nucleus

... predominantly nuclear proteins are now known to be localized to and function at the ...a nuclear transcription factor mediating senescence and apoptosis, but it also accumulates in the mitochondrial ...

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Oxadiazols: a New Class of Rationally Designed Anti-Human Immunodeficiency Virus Compounds Targeting the Nuclear Localization Signal of the Viral Matrix Protein

Oxadiazols: a New Class of Rationally Designed Anti-Human Immunodeficiency Virus Compounds Targeting the Nuclear Localization Signal of the Viral Matrix Protein

... govern nuclear import of the HIV-1 PIC (43). Three HIV-1 proteins, matrix protein (MA), integrase (IN), and viral protein R (Vpr), have been proposed as karyophilic agents that recruit the cellular ...

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A Nuclear Export Signal in the Matrix Protein of Influenza A Virus Is Required for Efficient Virus Replication

A Nuclear Export Signal in the Matrix Protein of Influenza A Virus Is Required for Efficient Virus Replication

... the nuclear retention of ...the nuclear export of ...the nuclear export of the NES-de- leted M1 ...than nuclear staining, and EGFP-M1 was evenly distributed between the nucleus and the ...a ...

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