Nucleic acid amplification tests (NAAT)
Comparison of Three Nucleic Acid Amplification Tests for Detection of Chlamydia trachomatis in Urine Specimens
... Johns Hopkins University, Baltimore, 1 and National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, 2 Maryland Received 14 January 2004/Returned for modification 17 March ...
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Evaluation of Six Commercial Nucleic Acid Amplification Tests for Detection of Neisseria gonorrhoeae and Other Neisseria Species
... laboratory tests that are sensitive, specific, reproducible, and robust because of nonspecific clinical manifestations or lack of symptoms in women as well as men ...(43). Nucleic acid ...
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Use of Multiple Nucleic Acid Amplification Tests To Define the Infected Patient “Gold Standard” in Clinical Trials of New Diagnostic Tests for Chlamydia trachomatis Infections
... 2004 Nucleic acid amplification tests (NAATs) can be used to define the infected-patient “gold standard” for the purpose of designing studies of the performance of Chlamydia trachomatis ...
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Towards Improved Accuracy of Bordetella pertussis Nucleic Acid Amplification Tests
... “Have no fear of perfection—you’ll never reach it.” —Salvador Dali T he laboratory diagnosis of pertussis has gone through funda- mental changes in the last 20 years. Culture and direct fluores- cent-antibody (DFA) ...
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Nucleic acid amplification tests in the diagnosis of tuberculous pleuritis: a systematic review and meta analysis
... in-house tests, both sensitivity and specificity estimates were significantly ...in-house tests. Conclusions: Our results suggest that commercial NAA tests may have a potential role in confirming ...
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Nucleic Acid Amplification Tests for Diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis Rectal Infections
... It is uncertain which methods for the diagnosis of rectal gonococcal and chlamydial infection are optimal. This study evaluated the performance of culture and nucleic acid amplification tests ...
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Diagnostic accuracy of nucleic acid amplification tests (NAATs) in urine for genitourinary tuberculosis: a systematic review and meta analysis
... severely. Nucleic acid amplification tests yield fast results, and among these, new technologies can also detect drug ...these tests in genitourinary tuberculosis; we therefore aimed to ...
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Comparison of the Luminex xTAG Respiratory Viral Panel with In House Nucleic Acid Amplification Tests for Diagnosis of Respiratory Virus Infections
... of nucleic acid amplification tests ...cleic acid probe can be conjugated to each bead, and a mixture of beads is used for detection and differentiation of products amplified in a ...
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Design and Validation of Transcription Mediated Amplification Nucleic Acid Amplification Tests for Mycoplasma genitalium
... of tests that detected rRNA and genomic DNA of ...DNA-based tests can decrease the rate of DNA-positive/RNA-positive consensus results obtained in the analysis, potentially resulting in artificially lowered ...
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Nucleic Acid Amplification Tests for Diagnosis of Neisseria gonorrhoeae Oropharyngeal Infections
... comparator tests to define infection, culture detected only 50% of the infections, while when we applied the more rigorous (more specific, but less sensitive) standard requiring the results of all three comparator ...
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Optimizing Screening for Acute Human Immunodeficiency Virus Infection with Pooled Nucleic Acid Amplification Tests
... Received 12 April 2007/Returned for modification 9 January 2008/Accepted 27 February 2008 Recent studies have shown the public health importance of identifying individuals with acute human immunodeficiency virus ...
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Performance of Clostridium difficile Toxin Enzyme Immunoassay and Nucleic Acid Amplification Tests Stratified by Patient Disease Severity
... stool tests in the diagno- sis of CDI is complicated by those patients who are asymptomat- ically colonized with ...laboratory tests must be interpreted in the context of patient symptoms and risk factors ...
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Comparison of Three Nucleic Acid Amplification Tests and Culture for Detection of Group B Streptococcus from Enrichment Broth
... three tests utilized has the potential to significantly increase sensitivity for GBS detection and reduce turnaround times while holding the potential to reduce infant morbidity/mortality particularly in large ...
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Impact of Patient Characteristics on Performance of Nucleic Acid Amplification Tests and DNA Probe for Detection of Chlamydia trachomatis in Women with Genital Infections
... that tests with relatively high sensitivity, such as NAAT, exhibit the greatest increase in sensitivity among women with presum- ably low organism burdens and that reasonably high specifici- ties are maintained in ...
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Nucleic Acid Amplification Tests for Diagnosis of Bordetella Infections
... Serology. Most cases of pertussis in older vaccinated chil- dren, in adolescents, and in adults are diagnosed by serological tests outside the United States. The enzyme-linked immu- nosorbent assay methodology and ...
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Evaluation of Nucleic Acid Amplification Tests as Reference Tests for Chlamydia trachomatis Infections in Asymptomatic Men
... reference tests might impose substantial burden and the TMA test has received limited evaluation with samples from asymptomatic ...reference tests are independent of the evaluated test for truly uninfected ...
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Clinical evaluation of commercial nucleic acid amplification tests in patients with suspected sepsis
... approved tests, needed no patient consent ac- cording to the Swedish ...diagnostic tests were made upon arrival to the emergency department and no additional sampling was ...available tests used for ...
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Relative Accuracy of Nucleic Acid Amplification Tests and Culture in Detecting Chlamydia in Asymptomatic Men
... the tests evaluated are probably not mutually in- dependent, even RSN and RFP estimates, which are less prone to bias than absolute estimates of sensitivity and specificity, may be ...all tests depend on ...
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A Systematic Review and Meta analysis of the Diagnostic Accuracy of Nucleic Acid Amplification Tests for Tuberculous Meningitis
... in-house tests and 28 commercial tests) that used culture as the reference standard and 24 data sets (21 in-house tests and 3 commercial tests) that used a ...NAA tests against culture ...
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Detection of Chlamydia trachomatis andNeisseria gonorrhoeae by Enzyme Immunoassay, Culture, and Three Nucleic Acid Amplification Tests
... only amplification assay with 100% specificity for detection of both ...cleic acid amplification tests (NAATs) have become widely used; these tests have shown a greater sensitivity and ...
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