Nucleoside diphosphate kinase (NDK)
SwoHp, a Nucleoside Diphosphate Kinase, Is Essential in Aspergillus nidulans
... a nucleoside diphosphate kinase ...a nucleoside triphosphate to a nucleoside diphosphate and are important in nucleotide metabolism (2, ...28). NDK null mutants of ...
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Dissecting the Unique Nucleotide Specificity of Mimivirus Nucleoside Diphosphate Kinase
... virus-encoded nucleoside diphosphate kinase (NDK), an enzyme that is central to the synthesis of RNA and DNA, ubiquitous in cellular organisms, and well conserved among the three domains of ...
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Role of Binding and Nucleoside Diphosphate Kinase A in the Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator by AMP-activated Protein Kinase
... tein kinase (AMPK) binds to and phosphorylates CFTR, attenu- ating PKA-activated CFTR ...that nucleoside diphosphate kinase A (NDPK-A) interacts with both AMPK and CFTR in overlay blots of ...
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Escherichia coli Strains (ndk) Lacking Nucleoside Diphosphate Kinase Are Powerful Mutators for Base Substitutions and Frameshifts in Mismatch-Repair-Deficient Strains
... Hamby, C. V., C. E. Mendola, L. Potla, G. Stafford and J. M. colorectal carcinoma syndrome. Cancer Res. 53: 5853–5855. Backer, 1995 Differential expression and mutation of NME Postel, E. H., S. J. Berberich, S. J. Flint ...
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Nm23/nucleoside diphosphate kinase-A as a potent prognostic marker in invasive pancreatic ductal carcinoma identified by proteomic analysis of laser micro-dissected formalin-fixed paraffin-embedded tissue
... Results: The two groups with poor prognosis (n = 4) and with better prognosis (n = 4) had been carefully chosen among 96 resected cases of pancreatic cancer during 1998 to 2007 in Tohoku University Hospital. Although ...
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Involvement of nucleoside diphosphate kinase b and elongation factor 2 in Leishmania braziliensis antimony resistance phenotype
... In the absence of effective vaccine against leishmaniasis, the only way to treat and control all forms of the disease is through the use of chemotherapy. Pentavalent antimo- nials are considered one of the main options ...
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Role of Interaction and Nucleoside Diphosphate Kinase B in Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Function by cAMP-Dependent Protein Kinase A
... protein kinase A (PKA) and ATP-regulated chloride ...that nucleoside diphosphate kinase B (NDPK-B, NM23-H2) forms a functional complex with ...
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Proliferation related expression of p19/nm23 nucleoside diphosphate kinase
... High level expression of the nm23-H1 gene, which encodes for a nucleoside diphosphate kinase, has been found to correlate with diminished metastasis in some tumors but not in others. We have ...
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Sharma, Rita (2006): Phosphorylation of chloroplast preproteins and the characterisation of nucleoside diphosphate kinase 2. Dissertation, LMU München: Fakultät für Biologie
... (Im et al., 2004), the authors applied in vitro binding assays to show that the C-terminal signal-transduction domain of phytochrome is critical for its interaction with NDPK2 protein. Since our experiments clearly show ...
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Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity
... exhibits nucleoside triphosphatase ...cellular nucleoside diphosphate (NDP) kinases, prompted us to investigate whether NSP2 exhibits phosphoryl-transfer ...NDP kinase-like activity that ...
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CSGID solves structures and identifies phenotypes for five enzymes in Toxoplasma gondii
... (PGMII), nucleoside diphosphate kinase (NDK), ribulose phosphate 3-epimerase (RPE), ribose-5-phosphate isomerase (RPI), and ornithine aminotransferase (OAT) were structurally ...
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Syndromes associated with mitochondrial DNA depletion
... mitochondrial nucleoside diphosphate kinase, resulting in mitochondrial dNTP pool imbalance and, eventually, low levels of mtDNA in muscle ...
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The UL97 gene product of human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase.
... thymidine kinase-deficient 143B cells infected with a recombinant vaccinia virus containing the entire UL97 open reading frame (ORF), as well as in HFF transiently expressing the entire UL97 ORF under the control ...
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Identification of a nucleoside analog active against adenosine kinase–expressing plasma cell malignancies
... Several pieces of evidence suggested that 6-ETI functions as an antimetabolite in PEL cells. Adenine derivatives with a 6-S sub- stitution have been extensively studied as anticancer and antiviral agents (37–39). The ...
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Metabolic engineering of Escherichia coli for production of mixed isoprenoid alcohols and their derivatives
... diacylglycerol diphosphate phos- phatase (DPP1) and lipid phosphate phosphatase (LPP1) from Saccharomyces cerevisiae have been evaluated for geraniol biosynthesis ...
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Purine Transport and Metabolism in Microvascular Endothelial Cells
... The in silico analysis of ENT1 predicted potential PKA phosphorylation sites (Figure 4.1), therefore the effects of PKA activators were investigated on nucleoside and nucleobase transport. Forskolin, an adenylate ...
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Reinvestigation of cadmium diphosphate
... Bond-valence sums (Brown, 2002) were computed at the end of the refinement using the softBV applet (Adams, 2004): Cd1 (six neighbours) 1.80 v.u., Cd2 (six) 2.12 v.u., P1 (four) 4.91 v.u. and P2 (four) 4.95 v.u., and a ...
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Efficient production of glycyrrhetinic acid in metabolically engineered Saccharomyces cerevisiae via an integrated strategy
... pyrophosphate; GPP: geranyl diphosphate; FPP: farnesyl diphosphate; GGPP: geranylgeranyl pyrophosphate; ERG10: acetyl-CoA C-acetyltransferase; ERG13: hydroxymethylglutaryl-CoA synthase;[r] ...
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The yin and yang functions of extracellular ATP and adenosine in tumor immunity
... Among P2Rs, P2X7R is the most potential candidate in anticancer therapy [96]. P2X7R was reported to be expressed in multiple malignant tumors, including neuroblastoma [97], melanoma [98], prostate cancer [99], lung ...
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A study on the OpenGL ES and the OpenSL ES in the Android NDK paradigm
... the NDK, the ADT and Eclipse are primarily what one requires to directly hit on towards Android Native ...Android NDK basically is a companion toolset for the Android SDK, designed to augment the SDK to ...
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