Nucleoside triphosphate
Mutational Analysis of Vaccinia Virus Nucleoside Triphosphate Phosphohydrolase I, a DNA-Dependent ATPase of the DExH Box Family
... virus nucleoside triphosphate phosphohydrolase I (NPH-I) is a DNA-dependent ATPase that serves as a transcription termination factor during viral mRNA ...acid-dependent nucleoside triphosphatases ...
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In Vitro Synthesis of Sindbis Virus Genomic and Subgenomic RNAs: Influence of nsP4 Mutations and Nucleoside Triphosphate Concentrations
... the nucleoside triphosphate concen- trations in the reaction mixtures and that introduction of these mutations into nsP4 and the promoter/template change the relative amounts of SG and G RNAs that are made, ...
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Nucleoside triphosphate diphosphohydrolase1 (TcNTPDase 1) gene expression is increased due to heat shock and in infective forms of Trypanosoma cruzi
... Ecto-nucleoside triphosphate diphosphohydrolases (Ecto- NTPDases, EC 3.6.1.5) are enzymes that hydrolyze tri- and/ or di-phosphate nucleotides [7,8]. Since extracellular ATP is an immune-modulatory molecule ...
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Role of Initiating Nucleoside Triphosphate Concentrations in the Regulation of Influenza Virus Replication and Transcription
... high nucleoside triphosphate (NTP) concen- tration during de novo-initiated replication to cRNA, whereas this is not the case for the extension of capped primers during transcription to ...
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Regulation of Synthesis of Two Immunologically Distinct Nucleic Acid-Dependent Nucleoside Triphosphate Phosphohydrolases in Vaccinia Virus-Infected HeLa Cells
... Enzymes identified as phosphohydrolases I and II on the basis of DNA-cellulose chromatography, requirement for nucleic acid cofactor, specificity for nucleoside triphosphate substrate, a[r] ...
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Tomato Ringspot Virus Proteins Containing the Nucleoside Triphosphate Binding Domain Are Transmembrane Proteins That Associate with the Endoplasmic Reticulum and Cofractionate with Replication Complexes
... Tomato ringspot virus (ToRSV) (genus Nepovirus, subgroup III, family Comoviridae) is a bipartite single-stranded, positive- sense RNA virus. Each RNA is covalently linked to a small virus-encoded protein (VPg) at its 5⬘ ...
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Stability of nucleoside triphosphate levels in the red cells of the snake
... of nucleoside triphosphate (NTP), largely in the form of ATP, which is found at concentrations of approximately 10 mmol l −−1 relative to cell volume and 15 mmol l −−1 relative to cell ...
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Mutational analysis of vaccinia virus nucleoside triphosphate phosphohydrolase II, a DExH box RNA helicase.
... virus nucleoside triphosphate phosphohydrolase II (NPH-II), a 3 -to-5 RNA helicase, displays sequence similarity to members of the DExH family of nucleic acid-dependent nucleoside triphosphatases ...
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Synthesis of Genomic and Subgenomic RNA in Mosquito Cells Infected with Two Sindbis Virus nsP4 Mutants: Influence of Intracellular Nucleoside Triphosphate Concentrations
... a nucleoside analog, the monophosphate form of which inhibits the enzyme orotate monophosphate (OMP) decarboxylase and thereby prevents the synthesis of both UTP and ...
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Poliovirus cis-Acting Replication Element-Dependent VPg Uridylylation Lowers the Km of the Initiating Nucleoside Triphosphate for Viral RNA Replication
... of nucleoside triphosphates (NTPs) re- quired for the initiation of viral RNA synthesis (NTPi) are typically greater than the concentrations required for the elon- gation of nascent RNA products ...
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Vaccinia virus nucleoside triphosphate phosphohydrolase I controls early and late gene expression by regulating the rate of transcription.
... The inhibition of early gene expression observed in cells infected with the mutant virus ts36 could be due to reduced levels of NPH-I protein being packaged into virions during growth of[r] ...
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Biosynthesis of 5-(4'5'-dihydroxypentyl) uracil as a nucleoside triphosphate in bacteriophage SP15-infected Bacillus subtilis.
... Although the deoxynucleoside of DHPU was not incorporated into SP15 DNA, the presence of DHPU, especially at the triphosphate level, in the acid-soluble pool of infected cells would indi[r] ...
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Identification of the vaccinia virus gene encoding nucleoside triphosphate phosphohydrolase I, a DNA-dependent ATPase.
... Conserved TAAATG sequence at the transcriptional and translational initiation sites of vaccinia virus late genes deduced by structural and functional analysis of the HindIII H genome fra[r] ...
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Vaccinia virions lacking the RNA helicase nucleoside triphosphate phosphohydrolase II are defective in early transcription.
... helicase nucleoside triphos- phate phosphohydrolase II (NPH-II) result in the production of noninfectious progeny virions at the restrictive ...by nucleoside monophosphate incorporation into acid-insoluble ...
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Presence of Nucleoside Triphosphate Phosphohydrolase Activity in Purified Virions of Reovirus
... From the data, it can be seen that i the reaction proceeds at 37 C but not at 0 C; ii virus must be activated for the activity to manifest itself; iii activity is directly proportional t[r] ...
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Synthesis of polynucleotide 5'-triphosphatase in vaccinia virus-infected HeLa cells.
... Effect of cytosine arabinoside on the synthesis of polynucleotide 5'-triphosphatase and nucleic acid-dependent nucleoside triphosphate phosphohydrolase activity in infected cells.. A dis[r] ...
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The Effects of Hypersaline Exposure on Oxygen Affinity of the Blood of the Freshwater Teleost Catostomus Commersoni
... Haematocrit Hct, haemoglobin Hb, mean cell haemoglobin concentration MCHC and nucleoside triphosphate concentration in blood from control CON, saline-acclimated S A L , SID-adjusted SI[r] ...
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Enzyme activities associated with an invertebrate iridovirus: nucleotide phosphohydrolase activity associated with iridescent virus type 6 (CIV).
... 12 cm with 0.5 M KH2PO4, pH 3.2, when dATP, ATP, or GTP was used as substrate, or 180 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest A nucleoside triphosphate phosphoh[r] ...
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Novel catalytic activity associated with positive-strand RNA virus infection: nucleic acid-stimulated ATPase activity of the plum pox potyvirus helicaselike protein.
... 1 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The cylindrical inclusion protein of potyviruses contains the so-called nucleoside triphosphate binding motif, acid se[r] ...
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Characterization of Genotypic Mutations and Antiretroviral Resistance among Viremic HIV Infected Patients in a High HIV Prevalence Area: Treatment Challenge and Transmission Risk
... There have been few reports evaluating the prevalence of genotypic mutations and antiretroviral resistance among chronic HIV-infected Veterans within the United States. This retrospective cross-sectional study ...
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