Nucleotide Metabolism
Salmonella Reprograms Nucleotide Metabolism in Its Adaptation to Nitrosative Stress
... The nucleotide alarmone ppGpp inhibits many of these processes (16, ...of nucleotide metabolism may allow salmonellae to avoid deleterious damage of DNA, lipids, and proteins by reactive nitrogen ...
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The effects of anaerobiosis on nucleotide metabolism during embryonic development of Artemia salina.
... suspend nucleotide metabolism and preserve its energy stores for further ...development. Nucleotide metabolism resumes when the availability of oxygen ...
32
Cyclic nucleotide metabolism during the development of murine thymic lymphoma
... causes a rapid increase in the activity ratio of hepatic cyclic AMP-PK followed by the induction of ornithine decarboxylase (ODC), the rate limiting enzyme in the biosynthetic pathway of polyamines. The induction of this ...
495
Deoxythymidine nucleotide metabolism in Bacillus subtilis W23 infected with bacteriophage SP1Oc: preliminary evidence that dTMP in SP10c DNA is synthesized by a novel, bacteriophage-specific mechanism.
... 1 Deoxythymidine Nucleotide Metabolism in Bacillus subtilis W23 Infected with Bacteriophage SPlOc: Preliminary Evidence that dTMP in SPlOc DNA Is Synthesized by a Novel, Bacteriophage-Sp[r] ...
8
The effects of cyclophosphamide and its derivatives on cyclic nucleotide metabolism
... It has been a useful generalisation that cyclic AMP inhibits and cyclic GMP promotes cell growth and that cancer cells have low cyclic AMP and high cyclic GMP levels (101). This holds true for some but not all cancerous ...
305
The platelet defect in leukemia Platelet ultrastructure, adenine nucleotide metabolism, and the release reaction
... adenine nucleotide metabolism of platelets from patients with acute leukemia were studied to elucidate possible mechanisms for the platelet dysfunction observed in this clinical ...
14
Characterisation of multiple substrate specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism
... different nucleotide substrates were tested for phosphatase ...cell nucleotide concentrations (12), we built a simple mathematical model for removal of ITP, dITP, XTP and dXTP in purine nucleotide ...
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Cyclic nucleotide metabolism in the streptozotocin diabetic rat corpus cavernosum; Relevance to human diabetic erectile dysfunction
... 4.5 Effect of VIP on cGMP synthesis by the penis, aorta and carotid artery of the rabbit 163 4.6 Effect of VIP on cGMP synthesis by the penis and aorta of control and diabetic rats [r] ...
299
THE EFFECT OF SPRINT TRAINING ON HUMAN SKELETAL MUSCLE PURINE NUCLEOTIDE METABOLISM
... Eight untrained subjects (six male and two female), performed a 30 s maximal sprint bout on a bicycle ergometer before and after a seven week intense sprint training regime. Venous blo[r] ...
166
FACTORS INFLUENCING MUSCLE PURINE NUCLEOTIDE METABOLISM
... that only two studies have examined the influence of allopurinol on purine metabolism following high intensity exercise in humans (Hadano et al. 1987; Sutton et al. 1980). Unfortunately, these studies have several ...
158
Regulation of endothelial cell cyclic nucleotide metabolism by prostacyclin
... A B S T R A C T An analysis of prostaglandin-stimulated adenosine 3',5'-cyclic monophosphate cyclic AMP accumulation in cultured human umbilical vein endothelial cells showed prostacycli[r] ...
8
c- myc and N- myc promote active stem cell metabolism and cycling as architects of the developing brain
... and nucleotide metabolism, mitosis, and chromatin structure as well as upregulation of genes associated with ...and metabolism as well as blocked ...
11
Highly Expressed Genes in Yeast Evolve Slowly
... Saccharo- nucleotide metabolism, the significant correlation be- myces genus before the genome duplication in yeast tween gene expression level and the rate of protein (Seoighe and Wolfe ...
5
Basal Nucleotide Levels, Release, and Metabolism in Normal and Cystic Fibrosis Airways
... The two prior reports of basal ATP release from normal and CF epithelia differ in their findings. These results (Fig. 2) are consistent with those of Grygorczyk et al., who did not detect differences in resting ATP ...
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Structural and Functional Constraints Limit Options for Cytotoxic T-Lymphocyte Escape in the Immunodominant HLA-B27-Restricted Epitope in Human Immunodeficiency Virus Type 1 Capsid
... synonymous nucleotide changes in seven longitudinal viral sequence pairs supports that the pre- dominant nucleotide substitution introduced during the repli- cative cycle of HIV-1 is a G-to-A transition, ...
12
The metabonomics study of P-selectin glycoprotein ligand-1 (PSGL-1) deficiency inhibiting the progression of atherosclerosis in LDLR-/- mice
... Atherosclerosis (AS) is a multi-factorial chronic disease commonly associated with the mechanisms of metabolism disorder, endothelial dysfunction and chronic inflammation. AS an inflammatory molecule, p-selectin ...
11
Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin based combinations
... the metabolism of many clinically available drugs [14-16] accounting for about 5% of the drugs used clin- ically ...amodiaquine metabolism in Caucasian population ...
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The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase
... Healthy cells mainly rely on oxidative phosphorylation to catabolise glucose, while cancer cells employ aerobic glycolysis to catabolise both glucose and glutamine [1]. Mitochondria coordinate the catabolism of glucose ...
6
Synergizing metabolic flux analysis and nucleotide sugar metabolism to understand the control of glycosylation of recombinant protein in CHO cells
... in metabolism during the culture time, such as growth rate, the rate of consumption and production of key metabolites and recombinant protein, and, also in some important culture conditions such as ...
17
Dynamic Changes in Serum Metabolomic Profiles of Growing Pigs Induced by Intravenous Infusion of Sodium Butyrate
... glycolipid metabolism, little is known on amino acid ...glutamate metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, cysteine and methionine metabolism, phenylalanine metabolism, ...
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