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nucleus/DNA

Proteolytic Cleavage of VP1-2 Is Required for Release of Herpes Simplex Virus 1 DNA into the Nucleus

Proteolytic Cleavage of VP1-2 Is Required for Release of Herpes Simplex Virus 1 DNA into the Nucleus

... Second, we identified VP1-2 as a virion protein that has to be proteolytically cleaved in order for DNA to be released from the capsids. (i) We show that in addition to full-length VP1-2, anti-VP1-2 N antibody ...

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The DNA damage response promotes polyomavirus JC infection by nucleus to cytoplasm NF  kappaB activation

The DNA damage response promotes polyomavirus JC infection by nucleus to cytoplasm NF kappaB activation

... the nucleus and stimulate the transcription of specific genes ...the DNA damage response (DDR) is also known to result in the activation of the NF-κB signaling pathway, a phenomenon known as nucleus ...

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Qualitative and quantitative characteristics of the extracellular DNA delivered to the nucleus of a living cell

Qualitative and quantitative characteristics of the extracellular DNA delivered to the nucleus of a living cell

... The DNA of chromosome fraction in the experiments under native conditions was not dissolved completely to reduce DNA degradation con- nected with dissolution but just left over 60 min for swell- ...

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DNA loops after cell lysis resemble chromatin loops in an intact nucleus

DNA loops after cell lysis resemble chromatin loops in an intact nucleus

... of DNA migration during the neutral comet ...of DNA mi- gration may be attributed to DNA loops with single- strand ...the DNA amount at this step increases, as it was shown in our earlier work ...

7

Mitochondrial DNA Heteroplasmy in Wheat, Aegilops and Their Nucleus-Cytoplasm Hybrids

Mitochondrial DNA Heteroplasmy in Wheat, Aegilops and Their Nucleus-Cytoplasm Hybrids

... A mitochondrial (mt) transcriptional unit, nad3-orf156, was studied in the nucleus-cytoplasm hybrids of wheat with D/D2 plasmons from Aegilops species and their parental lines. A comparative RFLP analysis and ...

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In-silico evaluation, analysis and screening of a potent polyphenolic herbal drug molecule and its validation as a candidate drug inhibiting p100/RELB domain of NF-kB alternate pathway through molecular docking studies

In-silico evaluation, analysis and screening of a potent polyphenolic herbal drug molecule and its validation as a candidate drug inhibiting p100/RELB domain of NF-kB alternate pathway through molecular docking studies

... recognition, DNA binding and interacting with inhibitory kB proteins is the responsibility of REL ...its DNA binding site and interfere with their ...

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Two Types of Recombination Hotspots in Bacteriophage T4: One Requires DNA Damage and a Replication Origin and the Other Does Not

Two Types of Recombination Hotspots in Bacteriophage T4: One Requires DNA Damage and a Replication Origin and the Other Does Not

... comet nucleus (Figure 3), suggesting that the X-arc molecules are re- lated to the comet molecules (Figure ...comet nucleus, the bubble arc, and the X arc (Figure 3), providing very strong evidence that the ...

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Wnt activated β-catenin and YAP proteins enhance the expression of non-coding RNA component of RNase MRP in colon cancer cells

Wnt activated β-catenin and YAP proteins enhance the expression of non-coding RNA component of RNase MRP in colon cancer cells

... the nucleus and recruits them to the promoter regions of the RMRP gene via TCF4 and TBX5 DNA binding proteins, which leads to elevated transcription of RMRP (Figure ...TCF/LEF DNA binding proteins, ...

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Intracellular redox-responsive nanocarrier for plasmid delivery: in vitro characterization and in vivo studies in mice

Intracellular redox-responsive nanocarrier for plasmid delivery: in vitro characterization and in vivo studies in mice

... enhanced DNA delivery and transfection efficiency in vitro and in ...plasmid DNA to low positively charged nanocomplexes, exhibited good stability against deoxy- ribonuclease I digestion, and tended to be ...

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Foamy Viruses Are Unconventional Retroviruses

Foamy Viruses Are Unconventional Retroviruses

... circular DNA and core and P proteins are thought to recycle into the nucleus of the infected cell where reverse transcription is ...the nucleus of multiple copies of active viral ...

9

The US16 Gene of Human Cytomegalovirus Is Required for Efficient Viral Infection of Endothelial and Epithelial Cells

The US16 Gene of Human Cytomegalovirus Is Required for Efficient Viral Infection of Endothelial and Epithelial Cells

... The human cytomegalovirus (HCMV) US12 gene family comprises a set of 10 contiguous genes (US12 to US21), each encoding a pre- dicted seven-transmembrane protein and whose specific functions have yet to be ascertained. ...

14

Nuclear Gln3 Import Is Regulated by Nitrogen Catabolite Repression Whereas Export Is Specifically Regulated by Glutamine

Nuclear Gln3 Import Is Regulated by Nitrogen Catabolite Repression Whereas Export Is Specifically Regulated by Glutamine

... bypass DNA binding and directly exit from the nucleus in glutamine-rich environments implies that its mechanism of exit depends on a change in Gln3 struc- ture, which, in turn, depends on Gln3 DNA ...

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EVALUATION OF CYTOTOXIC EFFECT OF PHOSKILL ON THE ROOT TIPS OF ALLIUM CEPA L

EVALUATION OF CYTOTOXIC EFFECT OF PHOSKILL ON THE ROOT TIPS OF ALLIUM CEPA L

... As an extension of abnormality stickiness the Lagging chromosome was observed at higher concentration. It showed that abonormality is strictly oriented with chemical interference on the cell cycle. The lagging behavior ...

7

Heavy flavors in nucleus-nucleus and proton-nucleus collisions

Heavy flavors in nucleus-nucleus and proton-nucleus collisions

... A nucleus-nucleus collision is a very complicated process undergoing several stages: right after the first interaction between the incident nuclei (or proton and nucleus) a dense system of partons is ...

10

Distribution of 2 [125I]iodomelatonin binding sites in the brain of the pied flycatcher (Ficedula hypoleuca) and the zebra finch (Taeniopygia guttata)

Distribution of 2 [125I]iodomelatonin binding sites in the brain of the pied flycatcher (Ficedula hypoleuca) and the zebra finch (Taeniopygia guttata)

... SP, nucleus semilunaris SLu) and in the nucleus isthmo-opticus (IO) of the tectofugal visual ...LPO, nucleus habenularis Hb), and nuclei related to vision (nuclei nervi oculomotorii OMD) and audition ...

7

Hypoplasia of Medullary Arcuate Nucleus in Unexpected Late Fetal Death (Stillborn Infants): A Pathologic Study

Hypoplasia of Medullary Arcuate Nucleus in Unexpected Late Fetal Death (Stillborn Infants): A Pathologic Study

... Transversal serial 5-␮m sections were made through the entire pons and medulla oblongata (approximately 600 sections per case). For each group of 12 sections, 3 were stained using alter- nately hematoxylin-eosin, ...

7

Real time measurement of Plasmodium falciparum infected erythrocyte cytoadhesion with a quartz crystal microbalance

Real time measurement of Plasmodium falciparum infected erythrocyte cytoadhesion with a quartz crystal microbalance

... possible blocking proteins should be performed to evalu- ate the potential of the methodology. One weakness of the system is that coating of a sugar as done with CSA might not represent the three-dimensional structure ...

9

Simulation of neutron production in hadron-nucleus and nucleus-nucleus interactions in Geant4

Simulation of neutron production in hadron-nucleus and nucleus-nucleus interactions in Geant4

... The FTF+Preco (FTFP), Bertini, Binary cascade model (BIC) and FTF+Binary cascade model (FTFB) calculations are also given. Preco and Binary Cascade models were added to the FTF model for the simulation of secondary slow ...

7

The Fragmentation Region of High Energy Nucleus-Nucleus and Hadron-Nucleus Collisions

The Fragmentation Region of High Energy Nucleus-Nucleus and Hadron-Nucleus Collisions

... The earliest studies of the production of the Quark Gluon Plasma in ultra-relativistic heavy ions col- lisions concerned the fragmentation region[1] . The energy considered was high enough so that the fragmentation ...

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