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Insights on Foxn1 Biological Significance and Usages of the “Nude” Mouse in Studies of T-Lymphopoiesis

Insights on Foxn1 Biological Significance and Usages of the “Nude” Mouse in Studies of T-Lymphopoiesis

... FoxN1-null nude mouse thymi, and found five FoxN1 target TEC genes in their microarray analysis, of which programmed cell death-1 ligand is the only gene of known function ...in nude thymic ...

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Application of Benchtop-magnetic resonance imaging in a nude mouse tumor model

Application of Benchtop-magnetic resonance imaging in a nude mouse tumor model

... Methods: We used a prototype of an in vivo BT-MRI apparatus to visualise organs and tumors and to analyse tumor progression in nude mouse xenograft models of human testicular germ cell tumor and colon ...

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Testing ATRA and MEK inhibitor PD0325901 effectiveness in a nude mouse model for human MPNST xenografts

Testing ATRA and MEK inhibitor PD0325901 effectiveness in a nude mouse model for human MPNST xenografts

... a nude mouse model to investigate if treatment of xenografts derived from NF1 associated S462 and T265 MPNST cells respond to ATRA and the MEKi ...Foxn1 nude mice but not in Balb/c, SHO or Shorn ...

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Development of a nude mouse model to study human sebaceous gland physiology and pathophysiology

Development of a nude mouse model to study human sebaceous gland physiology and pathophysiology

... Study of human sebaceous gland physiology and pathophysiology is limited by lack of an adequate animal model. This study was designed to develop an animal model using human face skin grafted onto the nude ...

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Original Article Impact of sex hormone on small cell lung carcinoma xenograft model in nude mouse

Original Article Impact of sex hormone on small cell lung carcinoma xenograft model in nude mouse

... of nude mice ...of nude mice, if there are growing tumor-like tissues, SCLC nude mouse model is successfully estab- ...experimental nude mice were under observation for spirit, respira- ...

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Epstein-Barr Virus Latent Nuclear Antigens Can Induce Metastasis in a Nude Mouse Model

Epstein-Barr Virus Latent Nuclear Antigens Can Induce Metastasis in a Nude Mouse Model

... of nude mice for up to 12 ...experimental nude mouse model by generating cell lines stably expressing the EBV latent antigens with or without Nm23-H1 expression, injecting these cells in nude ...

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Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model

Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model

... Colon cancer liver metastasis is often the lethal aspect of this disease. Well- isolated metastases are candidates for surgical resection, but recurrence is common. Better adjuvant treatment is therefore needed to reduce ...

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Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model

Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model

... To further investigate systemic rapamycin levels after top- ical rapamycin treatment, additional whole blood drug levels were obtained in control nude mice without tumors after single or multiple doses of ...

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Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors

Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors

... When grown in nude mice, cultured renal carcinoma cells from a hypercalcemic patient produced marked hypercalcemia that was reversed by resection of tumor. Conditioned medium from this cell line contained a ...

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Myxoma virus therapy of human embryonal rhabdomyosarcoma in a nude mouse model

Myxoma virus therapy of human embryonal rhabdomyosarcoma in a nude mouse model

... treated with MYXV-red was similar to that of the PBS-treated masses although inflammation was observed in all MYXV- red-treated tumors (Figure 3B). Inflammation was mild and mixed (neutrophils and mononuclear cells) in ...

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Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression

<p>Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression</p>

... the nude mouse model of subcutaneous A2780 xenograft was constructed, and then, Ado and cisplatin were administered intraper- itoneally to investigate the effect of Ado on tumor growth in ...

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PSGL 1–mediated activation of EphB4 increases the proangiogenic potential of endothelial progenitor cells

PSGL 1–mediated activation of EphB4 increases the proangiogenic potential of endothelial progenitor cells

... Endothelial progenitor cell (EPC) transplantation has beneficial effects for therapeutic neovascularization; how- ever, only a small proportion of injected cells home to the lesion and incorporate into the ...

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The herbal compound Songyou Yin (SYY) inhibits hepatocellular carcinoma growth and improves survival in models of chronic fibrosis via paracrine inhibition of activated hepatic stellate cells

The herbal compound Songyou Yin (SYY) inhibits hepatocellular carcinoma growth and improves survival in models of chronic fibrosis via paracrine inhibition of activated hepatic stellate cells

... a nude mouse model with liver fibrosis bearing orthotopic xenograft was established and we found that SYY could reduce associated fibrosis, inhibit tumor growth and improve ...in nude mice models ...

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Tumorigenicity of partial transformation mutants of Rous sarcoma virus.

Tumorigenicity of partial transformation mutants of Rous sarcoma virus.

... To determine whether any transformation parameters of the chicken cells were altered during the growth of the cells as tumors in a mammalian host, cultures derived from nude mouse tumors[r] ...

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Systemic IFN β gene therapy results in long term survival in mice with established colorectal liver metastases

Systemic IFN β gene therapy results in long term survival in mice with established colorectal liver metastases

... vivo nude mouse xenograft model for liver ...model, nude mice were inoculated intrahepatically with a human colorectal cancer cell line (KM12L4; kindly provided by ...

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A benign cultured colon adenoma bears three genetically altered colon cancer oncogenes, but progresses to tumorigenicity and transforming growth factor beta independence without inactivating the p53 tumor suppressor gene

A benign cultured colon adenoma bears three genetically altered colon cancer oncogenes, but progresses to tumorigenicity and transforming growth factor beta independence without inactivating the p53 tumor suppressor gene

... We describe the spontaneous progression of a colon adenoma cell line to tumorigenicity and growth factor independence. This system allows direct comparison of biologic stages of malignant progression with alterations of ...

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Magnetic Resonance Imaging of a Natural Killer Cell Therapy in a Mouse Model of Prostate Cancer

Magnetic Resonance Imaging of a Natural Killer Cell Therapy in a Mouse Model of Prostate Cancer

... a nude mouse model of prostate ...the mouse prostate and the whole mouse ...A mouse model that developed lymph node metastases was ...

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Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma

Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma

... orthotopic mouse model has been developed by implanting neuroblastoma into the fat pad of the mice ad- renal glands, which is the most common primary site of neuroblastoma in ...Furthermore, nude ...

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Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis

... orthotopic nude mouse ...6 nude mice in each cohort were presented. Left, whole mouse, upper right, lung, lower right, ...(One mouse in the control group died before the end of ...

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Study on the Effect of High Expression of Linker for Activated T Cells in Nude Mice Tumor Model

Study on the Effect of High Expression of Linker for Activated T Cells in Nude Mice Tumor Model

... In this research, a Jurkat cell nude mouse tumor model was established. The identification result shows that LAT can locate to lipid raft through palmitic acidification and can continue transducing signals. ...

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