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RAGE-aptamer Attenuates the Growth and Liver Metastasis of Malignant Melanoma in Nude Mice

RAGE-aptamer Attenuates the Growth and Liver Metastasis of Malignant Melanoma in Nude Mice

... We examined the effect of RAGE- aptamer on tumor growth as well as tumor-associated angiogenesis and macrophage infiltration in nude mice. Immunohistochemical analysis showed that PCNA-positive cell levels were ...

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A matrixial gaze : portrayals of the male nude by female artists

A matrixial gaze : portrayals of the male nude by female artists

... Figure 69: Berlinde De Bruyckere, Lange Enzeeme Man (Long Lonely Man), wax, epoxy, cushion, glass, wood, iron, 104.6 x 184.7 x 62.5 cm, private collection Mona, image Annie Geard ...

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Bufalin attenuates the stage and metastatic potential of hepatocellular carcinoma in nude mice

Bufalin attenuates the stage and metastatic potential of hepatocellular carcinoma in nude mice

... of nude mouse body weights among the four groups showed no significant ...groups nude mouse were much the ...in nude mice in a dose-dependent manner but had no effect on nude mouse ...

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Effect of Th9/IL-9 on the growth of gastric cancer in nude mice

<p>Effect of Th9/IL-9 on the growth of gastric cancer in nude mice</p>

... BALB/c nude mice were randomly divided into three groups: a normal control group (Control), an SGC-7901 xenografted nude mice model group (Model), and a rIL-9 treatment group ...

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Heterotopic erotic oases - the public nude beach experience

Heterotopic erotic oases - the public nude beach experience

... gay nude beach attracts users of a certain lifestyle, which often undertake activities not common to most ...gay nude beach, as heterotopia of crisis, is prompted by a subtle crisis, and is “privileged, ...

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Insights on Foxn1 Biological Significance and Usages of the “Nude” Mouse in Studies of T-Lymphopoiesis

Insights on Foxn1 Biological Significance and Usages of the “Nude” Mouse in Studies of T-Lymphopoiesis

... FoxN1-null nude mouse thymi, and found five FoxN1 target TEC genes in their microarray analysis, of which programmed cell death-1 ligand is the only gene of known function ...in nude thymic ...

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Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors

Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors

... When grown in nude mice, cultured renal carcinoma cells from a hypercalcemic patient produced marked hypercalcemia that was reversed by resection of tumor. Conditioned medium from this cell line contained a ...

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A novel GFP nude rat model to investigate tumor-stroma interactions

A novel GFP nude rat model to investigate tumor-stroma interactions

... as nude mice, nude rats as well as SCID mice have been extensively used in cancer research because they en- able xenografting of human cancer cells or biopsies, and thus generate models that more closely ...

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Original Article Homing of SPIO-MSCs to liver metastasis in nude mice

Original Article Homing of SPIO-MSCs to liver metastasis in nude mice

... the nude mouse xenograft, respectively. On the 9th day after injection, nude mice were anesthetized by ether and placed within ...9 nude mouse models were scanned and MRI images were ...experimental ...

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Myxoma virus therapy of human embryonal rhabdomyosarcoma in a nude mouse model

Myxoma virus therapy of human embryonal rhabdomyosarcoma in a nude mouse model

... Abstract: Rhabdomyosarcoma (RMS) is a devastating tumor of young people that is dif- ficult to cure. To determine if oncolytic virus therapy can improve outcomes in individuals with RMS, myxoma virus expressing a red ...

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Application of Benchtop-magnetic resonance imaging in a nude mouse tumor model

Application of Benchtop-magnetic resonance imaging in a nude mouse tumor model

... Eight week old male athymic-nude Foxn1 nu/nu mice (Harlan Winkelmann, Germany) were injected s.c. with 3 × 10 6 tumor cells in both flanks. NMR Imaging of mice was performed once a week. For comparison, the size ...

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Development of a nude mouse model to study human sebaceous gland physiology and pathophysiology

Development of a nude mouse model to study human sebaceous gland physiology and pathophysiology

... Study of human sebaceous gland physiology and pathophysiology is limited by lack of an adequate animal model. This study was designed to develop an animal model using human face skin grafted onto the nude mouse to ...

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Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model

Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model

... To further investigate systemic rapamycin levels after top- ical rapamycin treatment, additional whole blood drug levels were obtained in control nude mice without tumors after single or multiple doses of ...

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Characteristics of Viruses Derived from Nude Mice with Persistent Measles Virus Infection

Characteristics of Viruses Derived from Nude Mice with Persistent Measles Virus Infection

... the nude mouse brain in this study, the viral titers of the persistent viruses in the superna- tant of cell cultures were approximately 100-fold lower than those of the Edmonston strain before inoculation, and the ...

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Interferon-gamma inducible protein 10 (IP10) induced cisplatin resistance of HCC after liver transplantation through ER stress signaling pathway

Interferon-gamma inducible protein 10 (IP10) induced cisplatin resistance of HCC after liver transplantation through ER stress signaling pathway

... We also illustrated that over-expression of IP10 in HCC cells significantly promoted HCC cell proliferation and colony forming ability under cisplatin administration in vitro. In animal studies, three animal models were ...

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Original Article Small interfering RNA survivin and GRIM-19 co-expression salmonella plasmid inhibited the growth of laryngeal cancer cells in vitro and in vivo

Original Article Small interfering RNA survivin and GRIM-19 co-expression salmonella plasmid inhibited the growth of laryngeal cancer cells in vitro and in vivo

... fected cells had compareble GRIM-19 expres- sion to the negative control group. These results suggested that high expression of GRIM-19, possibly through specific inhibition of its downstream gene Stat3, indirectly ...

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The herbal compound Songyou Yin (SYY) inhibits hepatocellular carcinoma growth and improves survival in models of chronic fibrosis via paracrine inhibition of activated hepatic stellate cells

The herbal compound Songyou Yin (SYY) inhibits hepatocellular carcinoma growth and improves survival in models of chronic fibrosis via paracrine inhibition of activated hepatic stellate cells

... a nude mouse model with liver fibrosis bearing orthotopic xenograft was established and we found that SYY could reduce associated fibrosis, inhibit tumor growth and improve ...in nude mice models with ...

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FOXN1 deficient nude severe combined immunodeficiency

FOXN1 deficient nude severe combined immunodeficiency

... [20]. Nude SCID is an ex- ample of a SCID syndrome that is not due to mutation of a gene expressed in hematopoietic cells but rather consti- tutes an abnormality of the thymic stromal cell compart- ment, namely ...

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Inactivated FABP5 suppresses malignant progression of prostate cancer cells by inhibiting the activation of nuclear fatty acid receptor PPARγ

Inactivated FABP5 suppresses malignant progression of prostate cancer cells by inhibiting the activation of nuclear fatty acid receptor PPARγ

... been different hypotheses on how the androgen-dependent cells transform into androgen-independent cells. The main theory to date is that the biological sensitivity of AR is selectively amplified after the first round of ...

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Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms

Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms

... cell-deficient nude rats (NCI, Frederick, MD, USA) (280 to 320 g) or C57BL/6J wild-type mice (Jackson Labora- tory, Bar Harbor, ME, USA) and SCID mice (#001913; ...

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