o-H/sub 3/PO/sub 4/
Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>@Au composite magnetic nanoparticles in vitro and in vivo
... Fe 3 O 4 @Au composite MNPs were almost ingested and deposited in the liver because no nanoparticles and hemosiderosis were observed in other organs including heart, spleen, lung, kidney, and brain, ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... minor modifications. An aqueous solution of doxorubicin 5 mg/5 mL was emulsified in 10 mL dichloromethane, in which 120 mg of the copolymer and 4 mg magnetic nanopar- ticles had been dissolved, using a probe ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... sulfate [SDS], 20% glycerol) containing the protease inhibitor phenylmethanesulfonyl fluoride 0.1 mM/L. We separated 50 µ g of proteins on SDS–polyacrylamide gel electrophoresis 10%. Proteins were transferred to ...
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The effects of magnetite (Fe<sub>3</sub>O<sub>4</sub>) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH<sub>3</sub>) cells and in RAW 264.7 macrophages
... Fe 3 O 4 NPs on I MEP with a half-maximal inhibitory concentration (IC 50 ) value of 46 µ M could derive from the direct binding of the nanoparticles to the pores of the MEP-induced chan- ...Fe ...
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Preclinical studies of N<sub>3</sub>-O-toluyl-fluorouracil-loaded lipid-based nanosuspensions in H<sub>22</sub>-bearing mice
... Thus, the objective of the present study was to develop and characterize TFU-loaded LNS (TFU-LNS), so as to improve the bioavailability of TFU. In order to provide the basis for formulation design and rational use of ...
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Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... Fe 3 O 4 /Au nanoparticles were synthesized by assembling gold nanoparticles on SH-modified Fe 3 O 4 and using them as nanocarriers for immobilization of HRP and a secondary ...
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The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... (Fe 3 O 4 ) nanoparticles with appropriate surface modification, which have been widely used experimentally for numerous in vivo applications, such as magnetic resonance imaging, tissue repair, ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... Samples of tumor tissue weighing 0.1 g was collected from each mouse and homogenized for detection of P- glycoprotein, Bcl-2, Bax, and caspase-3. Briefly, the tissues were extracted with Triton X-100, and the ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... strategy is to treat tumor cells with antioxidants, such as through the dietary administration of red wine and green tea polyphenols to prevent cancer. The other strategy is to provide pro-oxidant therapy, which consists ...
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Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... Bis/Dex/Fe 3 O 4 and subjected to RF exposure. When Fe 3 O 4 was cultured with OBs and OCs under RF exposure, the cell survival rate declined to ~ ...Fe 3 O ...
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Effects of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> combinated with gambogic acid on apoptosis of SMMC-7721 cells
... Fe 3 O 4 -MNP and GA on apoptosis induction in SMMC-7721 ...Fe 3 O 4 -MNP at less than 20 μ g/mL concentration had no obvious influence on the multiplication of SMMC-7721 cells ...
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Co-encapsulation of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and doxorubicin into biodegradable PLGA nanocarriers for intratumoral drug delivery
... Abstract: In this study, the authors constructed a novel PLGA [poly(D,L-lactic-co-glycolic acid)]-based polymeric nanocarrier co-encapsulated with doxorubicin (DOX) and magnetic Fe 3 O 4 ...
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Effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and wogonin on the reversal of multidrug resistance in K562/A02 cell line
... for 4 hours at 4 ° C in ...at 4 ° C in 2% osmium tetroxide for 2 hours, and dehydrated in a graded series of ethanols and embedded in epoxy ...
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Characteristics of magnetic labeling on liver tumors with anti-alpha-fetoprotein-mediated Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... For these MFs, the hydrodynamic diameters of MNPs, as well as the MNPs with anti-AFP and anti-CEA coating, are 57.3 ± 15.2 nm, 54.3 ± 10.1 nm, and 54.4.0 ± 10.5 nm, respec- tively (Figure 2A). The measured saturation ...
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Inhibitory effect of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro
... Fe 3 O 4 had cooperative effect in suppression of tumor cell growth both in vivo and in ...HHT-MNP-Fe 3 O 4 could enhance the therapeutic efficiency by reducing the expression of ...
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Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... Fe 3 O 4 @SiO 2 -based drug delivery system that combines three properties: magnetic targeting, TfR targeting, and high DOX ...Fe 3 O 4 @ SiO 2 nanoparticle (DMP) was synthesized ...
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Capillary PO<sub>2</sub> does not adequately reflect arterial PO<sub>2</sub> in hypoxemic COPD patients
... c O 2 of ...a O 2 was ...a O 2 values ,60 mmHg showed a mean difference of - ...a O 2 values ,60 mmHg (data not pub- ...c O 2 and P a O 2 in the Ekkernkamp trial as well as in ...
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Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... MNPs-Fe 3 O 4 (State Key Lab of Bioelectronics, Nanjing, China) were well distributed in RPMI 1640 medium containing 10% (v/v) heat-inactivated new-born calf serum (Sijiqing, Hangzhou, China) by ...
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Magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells
... MNP-Fe 3 O 4 with different chemo- therapeutics may provide new clinical options in the treatment of ...MNP-Fe 3 O 4 with other compounds, eg, adriamycin, daunorubicin, and ...
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Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... Fe 3 O 4 (MNPs-Fe 3 O 4 ) could enhance the activity of artesunate (ART), and to explore its potential ...MNPs-Fe 3 O 4 on K562 cells was detected by MTT ...
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