Obese mice
2,4 Dinitrophenol Downregulates Genes for Diabetes and Fatty Liver in Obese Mice
... AL mice, both HFD mice and HFD+ 1.2 mg/kg LPS mice become obese with the heavier body weight (50 - 60 g vs 35 g) and higher body adipose percentage (8% - 10% vs 3%) after ...in obese ...
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Tissue Distribution and Regulation of Plasminogen Activator Inhibitor-1 in Obese Mice
... 6-fold) in PAI-1 mRNA expression observed in the epididymal, subcutaneous, and brown fat of the obese mice (Fig. 2) suggests that the adipose tissue itself may be a significant contribut[r] ...
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Myocutaneous revascularization following graded ischemia in lean and obese mice
... DIO mice, there was limited dilation of proximal flap vasculature and minimal neovas- cularization resulting in distal flap myocutaneous necrosis, most severe in DIO mice (Figure ...
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Remodeling of the arcuate nucleus energy balance circuit is inhibited in obese mice
... DIO mice results in both enhanced hypothalamic neu- rogenesis and long-term body weight loss ...in mice, com- paring those fed a standard diet with DIO ...DIO mice, genetically obese ...
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Prolonged transfer of feces from the lean mice modulates gut microbiota in obese mice
... and obese mice were housed in the same cage, the obese mice were protected from further weight gain by con- suming microbiota from lean ...lean mice eating feces from obese ...
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Expression of BMP4 in myocardium and vascular tissue of obese mice
... ob/ob mice were used as the experimental group, and C57BL/6 mice comprised the control ...of obese mice, and mediates local inflammatory ...
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Malaria and obesity: obese mice are resistant to cerebral malaria
... The obese ob/ob mice (C57BL/6 background) have developed a spontaneous recessive and nonsense punctual mutation in the leptin gene which, in the mutant ob/ob homozygote, encodes for a truncated ...
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Diet induced obese mice develop peripheral, but not central, resistance to leptin
... AKR mice were z 40 ng/ml after 168 d on a 45% fat diet ...fat-fed mice would have z 80 ng of total circulating ...of mice fed a 45% fat diet for up to 56 d, providing a fairly rigorous evalu- ation ...
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Adiponectin treatment attenuates inflammatory response during early sepsis in obese mice
... DIO mice and their corresponding control (CTRL) were purchased from Jackson Laboratories (Bar Harbor, ME, ...These mice were developed by feeding them with diets from Research Diets ...DIO mice were ...
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Weight gain and metabolic changes in obese mice fed with lyophilisedpitaia (hylocereus undatus)
... (Kowalska and Olejnik, 2016). Studies reveal the presence of bioactive components and seek to clarify their effects on the human body. A physical-chemical analysis (Sato et al., 2014)showed the low caloric density of the ...
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Growth hormone receptor regulates β cell hyperplasia and glucose stimulated insulin secretion in obese mice
... both obese control and βGHRKO mice became glucose intolerant (Figure 2B), but obese βGHRKO mice showed significantly higher glucose ...that obese βGHRKO mice responded to ...
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Metformin mitigates the impaired development of skeletal muscle in the offspring of obese mice
... OB offspring SM indicates that adipogenesis was upregu- lated, a conclusion confirmed by the presence of increased numbers of intramuscular adipocytes in OB offspring SM, detected in OB offspring SM. Maternal metformin ...
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The gut microbiome in cardio-metabolic health
... in obese mice [82]. In another study in mice, supplementa- tion with cholic acid protected against and even reversed diet-induced obesity; the effect was mediated by in- creased expression of the ...
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<p>Effects of liraglutide on lipolysis and the AC3/PKA/HSL pathway</p>
... wild-type mice. It is also found that TG of AC3 knockout mice is increased, and the fat mass of epididymal adipocytes of AC3 knockout mice is more than that of control ...in obese mice, ...
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Genistein treatment improves fracture resistance in obese diabetic mice
... experiment, mice were divided into four groups of equal size (n = 5), (1) lean mice fed a standard diet, (2) lean mice fed a genistein diet, (3) obese mice fed a standard diet, and (4) ...
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PubMedCentral-PMC4861228.pdf
... genetically obese mice (ob/ob) demonstrating a 50% reduction in abundance of the Bacteroidetes phylum and a parallel increase in Firmicutes phylum compared with wild-type siblings fed the same fat-heavy ...
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Effects of body weight and alcohol consumption on insulin sensitivity
... those mice that survive developed excess adiposity, adipocyte hyper- plasia, and increased circulating and tissue deposition of free fatty acids ...HF mice. Moreover, previously we showed that CR ...
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Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice
... in obese normo- tensive female mice than obese hypertensive male mice and were associated with increased adipose tissue ex- pression and activity of ...in obese male or obese ...
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Dietary supplementation with long-chain monounsaturated fatty acids attenuates obesity-related metabolic dysfunction and increases expression of PPAR gamma in adipose tissue in type 2 diabetic KK-Ay mice
... oleic acid or palmitoleic acid. As such, it is unclear whether MUFAs of greater chain length (> C18) have beneficial effects on obesity-related DM. Study of Greenland Eskimos shows their high consumption of food rich ...
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Tumor necrosis factor alpha contributes to obesity related hyperleptinemia by regulating leptin release from adipocytes
... and mice, showing a possible link between TNF- a and leptin production (19, ...normal mice to study the nature of TNF- a action as it re- lates to leptin secretion in ...in obese mice with a ...
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