Olfactory ensheathing cells (OEC)
Reconstruction of the Damaged Dorsal Root Entry Zone by Transplantation of Olfactory Ensheathing Cells
... Abstract The dorsal root entry zone is often used in research to examine the disconnection between the central and peripheral parts of the nervous system which occurs following injury. Our laboratory and others have used ...
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Transplantation of olfactory ensheathing cells on functional recovery and neuropathic pain after spinal cord injury; Systematic review and meta-analysis
... stem cells to neural supporting cells 7–11 . Olfactory ensheathing cells (OEC) are also viable candidates for cell therapy which can improve neuropathic pain and motor function in ...
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Anti bacterial properties of olfactory ensheathing cells and the primary olfactory pathway
... The olfactory pathway represents a potential route for pathogens to access the central nervous system (CNS) from the nasal ...understood. Olfactory ensheathing cells (OECs), glial cells ...
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Olfactory ensheathing cells are attracted to, and can endocytose, bacteria
... Keywords. Olfactory ensheathing cells, chemotaxis, endocytosis, innate immunity, ...The olfactory nerves are one set of peripheral nerves along which bacteria can invade the ...CNS. ...
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Transplantation of olfactory ensheathing cells in spinal cord injury
... between olfactory ensheathing cells and Schwann cells Originally, OECs were referred to as Schwann cells of the olfactory system (Doucette, 1984), but their distinctive ...
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Implantation of olfactory ensheathing cells promotes neuroplasticity in murine models of stroke
... Murine olfactory ensheathing cells (OECs) promote central nervous system axonal regeneration in models of spinal cord ...stem cells including intrinsic neural progenitor cells and bone ...
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Transplantation of olfactory ensheathing cells into spinal cord lesions restores breathing and climbing
... rat olfactory ensheathing cells when transplanted into large lesions that destroy all tracts on one side at the upper cervical level of the adult rat spinal ...
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Functional repair of the corticospinal tract by delayed transplantation of olfactory ensheathing cells in adult rats
... Division of Neurobiology, Norman and Sadie Lee Research Centre, Medical Research Council, National Institute for Medical Research, London, NW7 1AA, United Kingdom Adult rats were trained to use their forepaws to retrieve ...
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Co-Transplantation of Adipose Tissue-Derived Stromal Cells and Olfactory Ensheathing Cells for Spinal Cord Injury Repair
... stromal cells (ASCs) and olfactory ensheathing cells (OECs) have been used with promis- ing results in different models of SCI, namely due to the regenerative properties of the secre- tome of ...
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Transplanted olfactory ensheathing cells promote regeneration of cut adult rat optic nerve axons
... of olfactory ensheathing cells into spinal cord lesions promotes regeneration of cut axons into terminal fields and functional ...Schwann-like olfactory ensheathing ...these ...
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Effect of olfactory ensheathing cells (OECs) transplantation on functional recovery in acute phase of spinal contused rats
... Poor prognosis of patients is the motivation of searching a treatment for the chronic injury. Planting stem cells provides us with a promising strategy. In the meanwhile, the use of olfactory ...
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Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury
... cesses through CANSORT-SCI: Using Pet Dogs To Identify Effective Treatments for Spinal Cord Injury. J Neurotrauma. 2017; 34(12):2007–2018. https://doi.org/10.1089/neu.2016.4745 PMID: 28230415 37. Carwardine D, Wong L-F, ...
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Olfactory ensheathing cells moderate astrocyte inflammatory activation
... Espejo et al., 2002) by strongly activating NF-κB via oligodendrial p75 NTR (Ladiwala et al., 1998). TNF-α released by activated microglia could induce NF-κB translocation in OECs by a similar mechanism. Bacteria could ...
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Enhancing the Therapeutic Potential of Olfactory Ensheathing Cells in Spinal Cord Repair Using Neurotrophins
... the olfactory system envi- ronment, OECs aid and support the extension of axons from olfactory sensory neurons which reside in the olfac- tory mucosa in the peripheral nervous system ...of olfactory ...
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Original Article Transplantation of olfactory ensheathing cells promotes partial recovery in rats with experimental autoimmune encephalomyelitis
... of olfactory ensheathing cell (OEC) transplantation on experimental autoimmune encephalomyelitis ...the olfactory nerve layer of SD rats, and then transplanted to the EAE models through the vena ...
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Improving the regenerative potential of olfactory ensheathing cells by overexpressing prostacyclin synthetase and its application in spinal cord repair
... sequential action of cyclooxygenase (COX)-1 or −2 and prostacyclin synthase from arachidonic acid (AA) which is deacylated from cellular phospholipids [23]. Prosta- glandin or leukotriene were rapidly produced following ...
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Neuroregenerative effects of olfactory ensheathing cells transplanted in a multi-layered conductive nanofibrous conduit in peripheral nerve repair in rats
... the cells to grow as compared to simple hollow film conduits; this trans- lates into transplanting greater number of cells into the defect ...Schwann cells in axon mye- lination might have led to ...
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Anti bacterial properties of olfactory ensheathing cells and the primary olfactory pathway
... The above procedure was repeated with the remaining rats. The tissues were then digested by addition of 0.25% trypsin + 0.03% collagenase solution for 15mins at 37 o C. The supernatant was removed and replaced with fresh ...
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Why are olfactory ensheathing cell tumors so rare?
... glial cells of the primary olfactory nervous system, olfactory ensheathing cells (OECs), are unusual in that they rarely form ...primary olfactory nervous system is a highly ...
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The Impact of Tissue Storage Conditions on Rat Olfactory Ensheathing Cell Yield and the Future Clinical Implications.
... that olfactory ensheathing cells (OECs) are a unique type of glial cell and they can promote regeneration of CNS axons to aid recovery after spinal cord ...the olfactory bulb (OB), is ...
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