Onchocerca ochengi
Efficacy of Three-Week Oxytetracycline or Rifampin Monotherapy Compared with a Combination Regimen against the Filarial Nematode Onchocerca ochengi
... nematode Onchocerca volvulus, is a major cause of visual impairment and dermatitis in sub-Saharan ...(Onchocerca ochengi) in ...O. ochengi than oxytetracycline ...
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Characterisation of a novel glycosylated glutathione transferase of Onchocerca ochengi, closest relative of the human river blindness parasite
... nematode Onchocerca ochengi, which is homologous (99% amino acid identity) with an immunodominant GST and potential vaccine candidate from the human parasite, ...(OvGST1b). Onchocerca ochengi ...
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UMF 078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle
... Using Onchocerca ochengi, a natural parasite of cattle that is endemic in the Adamawa province of Cameroon [19], the efficacy of UMF-078 was assessed in vivo by the intramuscular or intraabomasal routes at ...
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Characterisation of a novel glycosylated glutathione transferase of Onchocerca ochengi, closest relative of the human river blindness parasite
... nematode Onchocerca ochengi is a well-established model natural system for the study of human onchocerciasis, the causative agent of which is ...the Onchocerca spp genomes reveal a glutathione ...
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Further evidence of the cross reactivity of the Binax NOW® Filariasis ICT cards to non Wuchereria bancrofti filariae: experimental studies with Loa loa and Onchocerca ochengi
... Onchocerca ochengi adult males Cattle skin collected from a local slaughter house was transported on ice to the laboratory within an ...viability. Onchocerca ochengi adult males were washed 3 ...
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Phytochemical analysis and in vitro anthelmintic activity of Lophira lanceolata (Ochnaceae) on the bovine parasite Onchocerca ochengi and on drug resistant strains of the free living nematode Caenorhabditis elegans
... this plant has not yet been evaluated on filarial worms. In this study, we investigated the claimed filaricidal activities of L. lanceolata against the bovine parasite Onchocerca ochengi. This parasite is ...
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In vitro anti Onchocerca ochengi activities of extracts and chromatographic fractions of Craterispermum laurinum and Morinda lucida
... [28]. Onchocerca ochengi, found exclusively in cow is the closest relative to the medically important ...against Onchocerca ochengi parasite ...
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Stage-specific proteomes from Onchocerca ochengi, sister species of the human river blindness parasite, uncover adaptations to a nodular lifestyle.
... agent, Onchocerca volvulus, is a filarial nematode with a complex lifecycle involving several distinct stages in the definitive host and blackfly ...parasite Onchocerca ochengi, to compare ...
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Onchocerca infected cattle produce strong antibody responses to excretory secretory proteins released from adult male Onchocerca ochengi worms
... A semi-quantitative analysis of serum IgG antibody levels was performed by ELISA to find antibody end- points, as described previously by Mpagi et al. [27] with modifications adapted to the analysis of cattle sera. As ...
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Filaricidal activities on Onchocerca ochengi and Loa loa, toxicity and phytochemical screening of extracts of Tragia benthami and Piper umbellatum
... After investigating the filaricidal activity of the ex- tracts, it was necessary to investigate their safety. This was done by evaluating cytotoxicity on LLC-MK2 cells for the 9 extracts that were active on female worms, ...
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Development and validation of an Onchocerca ochengi microfilarial hamster model for onchocerciasis drug screens
... O. ochengi mf, three preliminary exploratory experiments were done with different numbers of mf injected in each animal (Table ...O. ochengi mf in the skin detected on day 21 and 30 when the animals were ...
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Selective activity of extracts of Margaritaria discoidea and Homalium africanum on Onchocerca ochengi
... dabbed with a clean tea cloth to eliminate excess moist- ure, and covered entirely with 70% ethanol. The latter was allowed to evaporate completely in a horizontal flow sterile hood. The ethanol treatment was repeated ...
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Of Mice, Cattle, and Humans: The Immunology and Treatment of River Blindness
... Figure 1. Life cycle of Onchocerca volvulus and Onchocerca ochengi . Adult female worms initiate the formation of nodules in the skin (onchocercomas) (see Figures 2 and 3) in which their highly ...
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Redescription of Onchocerca lupi (Spirurida: Onchocercidae) with histopathological observations
... genus Onchocerca Diesing, 1841 (Spirurida, Oncho- cercidae) includes parasitic species of vast medical inter- est, mainly due to Onchocerca volvulus (Leuckart, 1893), which infects humans in tropical ...
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Immunohistochemical Study on lipid Catabolism in Adult Onchocerca Volvulus
... Abstract: Onchocerca volvulus is a parasite responsible for the disease, Onchocerciasis otherwise known as river blindness. Current treatment and control strategies are not entirely successful. This means there is ...
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Patent infections with soil transmitted helminths and Schistosoma mansoni are not associated with increased prevalence of antibodies to the Onchocerca volvulus peptide epitopes OvMP 1 and OvMP 23
... The assessment of cross-reactivity with other related and/ or co-endemic infectious agents is a critical part of the analytical validation of novel diagnostic tools. Hence, this work represents an essential part of the ...
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A cryptic species of Onchocerca (Nematoda: Onchocercidae) in blackflies (Simulium spp ) from southern California, USA
... of Onchocerca, in conjunction with the emergence of the zoonotic ...within Onchocerca from North ...cryptic Onchocerca species originally documented in white-tailed deer from New York ...
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Stage Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont
... ABSTRACT Onchocerciasis (river blindness) is a neglected tropical disease that has been successfully targeted by mass drug treatment programs in the Americas and small parts of Africa. Achieving the long-term goal of ...
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Defining parasite biodiversity at high latitudes of North America: new host and geographic records for Onchocerca cervipedis (Nematoda: Onchocercidae) in moose and caribou
... Disease emergence associated with climatic conditions and new host associations has been reported for related arthropod-borne filarioids of ungulates at higher lati- tudes. For example, peritonitis epizootics caused by ...
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Vector borne helminths of dogs and humans in Europe
... threatening dogs and cats, whereas D. repens, causing subcutaneous infestation in dogs, is the main agent of human dirofilariosis. Although Dirofilaria spp. above represent key examples of the success of this group of ...
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