Onchocerca volvulus
Rapid Point-of-Contact Tool for Mapping and Integrated Surveillance of Wuchereria bancrofti and Onchocerca volvulus Infection
... and Onchocerca volvulus are in critical need of sensitive, specific, and point-of- contact (POC) tools that can be used for surveillance years beyond cessation of mass drug administration when infection ...
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A Simple Isothermal DNA Amplification Method to Screen Black Flies for Onchocerca volvulus Infection
... Onchocerciasis is a debilitating neglected tropical disease caused by infection with the filarial parasite Onchocerca volvulus. Adult worms live in subcutaneous tissues and produce large numbers of ...
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Onchocerca volvulus as a risk factor for developing epilepsy in onchocerciasis endemic regions in the Democratic Republic of Congo: a case control study
... who participated in an epilepsy survey were found to present with episodes of epileptic seizures. Individual risk of epilepsy was found to be associated with living close to the Bima river, a fast-flowing River where ...
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Wolbachia endosymbiont of Onchocerca volvulus: driver of immunopathology and target for therapy
... including Onchocerca volvulus, has revolutionised the understanding of the parasite’s biology and immunopathogenic mechanisms of disease, and has offered a novel approach to its treatment and control with ...
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Individual exposure to Simulium bites and intensity of Onchocerca volvulus infection
... Background: Onchocerca volvulus, the causative agent of river blindness, is transmitted through the black fly Simulium damnosum s.l., which breeds in turbulent river waters. To date, the number of flies ...
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Discrimination between Onchocerca volvulus and O ochengi filarial larvae in Simulium damnosum (s l ) and their distribution throughout central Ghana using a versatile high resolution speciation assay
... Onchocerca volvulus is a human filarial parasite respon- sible for the disease onchocerciasis, and is transmitted between hosts by blackflies of the genus ...an Onchocerca- specific O-150 polymerase ...
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Modelling Neglected Tropical Diseases diagnostics: the sensitivity of skin snips for Onchocerca volvulus in near elimination and surveillance settings
... patent Onchocerca volvulus infection, and the World Health Organization recommends their use to monitor progress of treatment programmes (but not to verify ...
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Immunoglobulin G subclass responses of children during infection with Onchocerca volvulus.
... where Onchocerca volvulus is endemic, and these samples were tested by enzyme- linked immunosorbent assay for their reactivity to adult antigens (OvAg) and against four recombinant proteins (OV11, OV27, ...
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Not every worm wrapped around a stick is a guinea worm: a case of Onchocerca volvulus mimicking Dracunculus medinensis
... After reporting its first case in 1967, Cameroon with the support of international partners put in place mech- anisms to control the disease. In 1997, the last confirmed case was reported and in 2007 the country was ...
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Retarded Onchocerca volvulus L1 to L3 larval development in the Simulium damnosum vector after anti wolbachial treatment of the human host
... with Onchocerca volvulus Before and after treatment, the volunteers were brought to a pre-selected ...O. volvulus-free capture point near a Simulium breeding site on the bank of the River Mungo to ...
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Biting behaviour of Simulium damnosum complex and Onchocerca volvulus infection along the Osun River, Southwest Nigeria
... Though, none of the flies were infected, the value of ABR recorded in each of the three sampling points dur- ing this study was far above the threshold biting rate usually considered for onchocerciasis transmission by ...
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Extracts of Euphorbia hirta Linn (Euphorbiaceae) and Rauvolfia vomitoria Afzel (Apocynaceae) demonstrate activities against Onchocerca volvulus Microfilariae in vitro
... by Onchocerca volvulus is the second major cause of blindness in the world and it impacts negatively on the socio-economic development of the communities ...O. volvulus resistance to ...
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Isolation and characterization of expression cDNA clones encoding antigens of Onchocerca volvulus infective larvae
... The isolation of recombinant cDNA clones expressing antigens found in Onchocerca volvulus infective larvae is described. To isolate such clones, an expression cDNA library constructed from adult O. ...
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Significant heterogeneity in Wolbachia copy number within and between populations of Onchocerca volvulus
... O. volvulus harbour endosymbiotic Wolbachia bacteria [3, 4] and, in ...O. volvulus, it is proposed that the bacteria, rather than the nematode itself, drive the immunopathology associ- ated with the disease ...
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Assessment of multiplex Onchocerca volvulus peptide ELISA in non endemic tropical regions
... O. volvulus in Kenya, a result that is in strong disagreement with the epidemiology of onchocer- ...O. volvulus epitopes are recognized by antibodies induced by either/or ...O. volvulus and yet ...
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Serological cross reactivity between a human Ro/SS A autoantigen (calreticulin) and the lambda Ral 1 antigen of Onchocerca volvulus
... We have cloned and sequenced a 46-kD Ro/SS-A autoantigen gene that is the human homologue of the calcium-binding protein, calreticulin. The sequence of this 46-kD Ro/SS-A protein (calreticulin) has significant homology ...
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Interruption of Onchocerca volvulus transmission in Northern Venezuela
... O. volvulus in children up to 5 years of age that had not received treat- ment ...3 Onchocerca volvulus infection in the human population (sentinel community of Santa Rosa del ...
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An isothermal DNA amplification method for detection of Onchocerca volvulus infection in skin biopsies
... Isothermal amplification provides a simple process that rapidly and efficiently accumulates nucleic acids at constant temperature [25]. In contrast to PCR-based amplification, no temperature cycles are required, which ...
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Immunohistochemical Study on lipid Catabolism in Adult Onchocerca Volvulus
... Abstract: Onchocerca volvulus is a parasite responsible for the disease, Onchocerciasis otherwise known as river ...O. volvulus can operate the B-oxidative pathway, The TCA cycle, and undergo ...
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Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity
... O. volvulus populations, but that reduction or interruption of transmission and reduc- tion in population size by ivermectin treatment, and/or migration from untreated into treated populations also drives drift ...
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