One-pot multi-component reaction
![An one pot multi component synthesis of novel 1,2,4 triazolo[1,5 a]pyrimidines](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
An one pot multi component synthesis of novel 1,2,4 triazolo[1,5 a]pyrimidines
... classical one-pot Biginelli reaction [5, 14-17] and in some cases on more complex multi-step processes involving harsh reaction conditions and long reaction ...[18-19] One ...
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NBS/AIBN promoted one pot multi component regioselective synthesis of spiro heterobicyclic rings via Biginelli like condensation reaction
... four-component reaction is described, leading to the efficient regioselective synthesis of σ symmetric spiro heterobicyclic rings using aldehydes and urea in the presence of cyclic β-diester or β-diamides ...
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ONE-POT MULTI-COMPONENT SYNTHESIS OF [1,4]BENZOXAZINE- ISOXAZOLE HYBRIDS AND THEIR ANTIBACTERIAL ACTIVITY
... A one-flask strategy for the synthesis of novel 4-((3-(aryl) isoxazol-5-yl) methyl)-2H-benzo[b][1,4] oxazin-3(4H)-one derivatives (4a-j) were synthesized by the Cu(I)-catalyzed reaction of in situ ...
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Application of tris (trihexyltetradecylphosphonium) gadolinium hexachloride as magnetically recoverable catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones in solvent-free conditions
... the one-pot multi-component synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives has been developed by one pot three component reaction of various ...
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An Efficient Method For The One-Pot, Four-Component Benzaldehyde Based Synthesis of 3-Methyl-1,4-Diphenyl-7,8-Dihydro-1H-Furo[3,4-E]Pyrazolo[3,4-B]Pyridin-5(4H)-Ones Catalyzed by Alum in Environment-Friendly Media.
... Application of multicomponent reactions (MCRs) to the construction of natural product-based libraries would be most beneficial to this area of research. Such processes in which three or more reactants are combined ...
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DABCO Promoted Multi-Component one-pot Synthesis of Xanthene Derivatives
... A wide variety of methods for the preparation of the xanthenes have been reported 13-19 . However, many of these methods are associated with several short comings such as long reaction times (16 h to 5 days), ...
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Cyclohexane-1,4-diyl bis (hydrogen sulfate) as an efficient homogeneous catalyst for one-pot multi-component synthesis of dihydropyrimidones via Biginelli reaction
... such as H 4 PMo 11 VO 40 [6], Fe 3 O 4 -MWCNT [7], CaF 2 [8], MgBr 2 [9], NbCl 5 [10], Ce(C 12 H 25 SO 3 ) 3 [11], ErCl 3 [12], Mo/γ-Al 2 O 3 [13], Fe 3 O 4 @Nb 2 O 5 [14], and graphite- LaCl 3 [15]. Another type of ...
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An eco friendly solvent free one pot multi component synthesis of Coumarin thiazolidinone derivatives
... the reaction; thus we believed that the present methodology opens new possibilities for the green synthetic organic chemistry and could be an important addition to existing methodologies, in our experiments, the ...
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Application of one pot three component condensation reaction for the synthesis of new organophosphorus sulfur macrocycles
... are one of efficient solutions to tackle this challenge; a wide range of components can be chosen to one-pot reactions which can fully meet the principle with atom economy and step ...efficient ...
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An Efficient Synthesis of Functionalized 3-(α-amidobenzyl)-4-hydroxycoumarin Derivatives by ZnO Nanoparticles Promoted Condensation Reaction Between Aromatic Aldehyde, 4-hydroxycoumarin, and Amides
... Multi-component reactions have been attracting much interest from synthetic chemists because they provide simple one-pot routs for the synthesis of complex molecules from simple and easily ...
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One Pot Multi Component Synthesis of Novel Dihydropyridine Derivatives
... In conclusion, aryl heterocyclic aldehydes (2a-e) were used as starting materials for the synthesis of new biologically active heterocyclic dihydropyridine derivatives (1a-e) by using ethyl acetoacetate 3 and ammonium ...
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MULTI-COMPONENT REACTION SYNTHESIS OF 1,6-DIAMINO-2-OXO-1,2,3,4-TETRAHYDROPYRIDINE-3,5-DICARBONITRILES USING ULTRASONICATION AND DMAP AS CATALYST
... are one-pot procedures for synthesis of an individual product in the reaction between three or more available components, attained in a one-step without isolation of any intermediate ...
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Synthesis of benzo[f]chromeno[3,4-b]quinoline-6-ones and chromeno[3,4-b]quinoline-6,11-diones via one-pot three-component tandem Knoevenagel–Michael reaction catalyzed by n-Tetrabutylammonium tribromide
... develop multi-component reactions to synthesize prospective bioactive scaffolds [58, 59], we would like to report one-pot three-component reaction for synthesising ...
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Heterogeneous Catalyst for the One-Pot Synthesis of 1,8-Dioxodecahydroacridine
... via multi- component one-pot Hantzsch reaction of various aldehydes and ammonium acetate with 2 equivalents dimedone in the presence of Phosphorus pentoxide supported on aluminaas ...
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Nano Nickel Cobalt Ferrite Catalysed One Pot Multi Component Synthesis of Xanthenediones and Acridinediones
... and reaction of aryloxy magnesium halides with triethyl orthoformate [14] as well as cyclo-condensation of 2-hdroxyl aromatic aldehyde with 2-tetralone ...is one of the commonly utilized ...
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Ultrasonic Accelerated Efficient Synthesis of (1H-tetrazole-5-yl) Pyrazines Catalyzed by MgFe2O4 Nanoparticles as a Reusable Heterogeneous Catalyst
... by one pot multi- component coupling reaction of α-dicarbonyl compounds, 2,3-diaminomaleonitrile and sodium azide using MgFe 2 O 4 nanoparticles as a robust catalyst under ultrasonic ...
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Benzethonium Chloride Catalyzed one Pot Synthesis of 2,4,5-Trisubstituted Imidazoles and 1,2,4,5-Tetrasubstituted Imidazoles in Aqueous Ethanol As A Green Solvent
... the reaction was monitored by TLC. After completion of the reaction as indicated by TLC, the reaction mixture was cooled to room ...The reaction volume was reduced and diluted with ...
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A Rapid and Highly Effectual Protocol for the Synthesis of Bis-coumarins using Triethylaminium-N-sulfonic Acid Tetrachloroaluminate under Solvent-Free Conditions
... In this work, a rapid and highly effectual protocol for the synthesis of bis-coumarins has been developed. The one-pot quasi three-component reaction of aromatic aldehydes (1 eq.) with ...
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A New and Efficient Method for the Synthesis of Pyrimido[2,1 b]Benzothiazole Derivatives
... densation reaction (MCR) that is one of the most useful methods for the synthesis of organic compounds in an optimistic time and only in a single ...aforementioned reaction most often leads to ...
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Multicomponent One-Pot Synthesis and Biological Evaluation of Pyrano[2,3-C] Pyrazoles
... The corresponding β-keto esters were synthesized either according to Yuasa and Tsuruta [8] or by deprotonation of esters and subsequent reaction with ethyl acetate. This second procedure (deprotonation of esters), ...
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