Open Field Test
EVALUATION OF ANTIDEPRESSANT ACTIVITY OF ACYRANTHES ASPERA BY USING OPEN FIELD TEST IN RATS
... using open field test apparatus so I decided to evaluate the antidepressant effect of Acyranthes aspera extract by using open field ...
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Controlled progressive innate immune stimulation regimen prevents the induction of sickness behavior in the open field test
... Abstract: Peripheral immune activation by bacterial mimics or live replicating pathogens is well known to induce central nervous system activation. Sickness behavior alterations are often associated with ...
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IN VITRO AND IN VIVO BIOLOGICAL INVESTIGATIONS OF THE WHOLE PLANT EXTRACTS OF CHROZOPHORA PROSTRATA (DALZ.)
... Open field test (OFT): According to Gupta et ...modification open field test was performed to monitor behavioral responses in mice that were placed in a novel and bright ...The ...
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... anxiety rate, motor activity, and cognitive abilities using the respective behavioural tests: open field test, dark/light box, and the extrapolation escape test. The offspring of rats exposed ...
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Abnormalities in perineuronal nets and behavior in mice lacking CSGalNAcT1, a key enzyme in chondroitin sulfate synthesis
... T1 enzyme deficiency caused behavioral abnormalities including abnormalities in the open field test, social inter- action test, and acoustic startle response (Fig. 4). These re- sults suggest ...
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IN VITRO CYTOTOXIC AND IN VIVO ANXIOLYTIC STUDY OF METHANOLIC CRUDE EXTRACT OF STRECULIA VILLOSA SEEDS
... cross test, open field test, elevated plus-maze (EPM) test, thiopental sodium induced sleeping time test in Swiss albino mice for the first time [3] ...
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Antioxidative and neuroprotective effects of Leea macrophylla methanol root extracts on diazepam-induced memory impairment in amnesic Wistar albino rat
... by open field test, hole cross test, elevated plus maze test and thiopental sodium induced sleeping time test for screening neuropharmacological effect on Wistar albino rats ...
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Evaluation of Acute Toxicity and Sedative Effects of Ethylic Extract of Thymelaea lythroides in Wistar Rats
... The Open Field test task approaches the conflict between the rats’ desire to explore new environments versus the innate fear that they have of the central area of a novel or brightly lighted ...
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Porphyromonas gingivalis lipopolysaccharide induces cognitive dysfunction, mediated by neuronal inflammation via activation of the TLR4 signaling pathway in C57BL/6 mice
... Methods: The C57BL/6 mice were injected with P. gingivalis-LPS (5 mg kg −1 ) either with or without Toll-like receptor 4 (TLR4) inhibitor (TAK-242, 5 mg kg −1 ). After 7 days, behavioral alterations were assessed with ...
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Evaluation of anxiolytic and antidepressant effect of different dosage forms of the Guduchi
... the field of psychopharmacology many of ayurvedic dosage forms are being researched for their anxiolytic and antidepressant ...using open field test, elevated plus maze test in anxiety ...
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ANXIOLYTIC ACTIVITY OF GABAPENTIN, PREGABALIN, SODIUM VALPROATE AND ALPRAZOLAM IN WISTAR ALBINO RATS A COMPARATIVE STUDY
... of open field test, rats treated with alprazolam, sodium valproate, gabapentin showed a significant ...all test drugs treated rats showed significant increase in the number of rearing Vs ...
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Neuropharmacological activity of the crude ethanolic extract of Syzygium aromaticum flowering bud
... using open field test (OFT), hole cross test (HCT), elevated plus maze (EPM), and hole board test (HBT) respectively; while antidepressant properties were determined using forced ...
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ANTIANXIETY, ANTICONVULSANT, MYORELAXANT AND HYPNOTIC EFFECT OF POLYHERBAL EXTRACTS ON RODENTS
... board test, open field test), anticonvulsant (MES induced convulsions), myorelaxant action (rotarod) and hypnotic property (Phenobarbital-induced sleeping) in suitable animal ...
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Tumour necrosis factor - alpha mediated mechanisms of cognitive dysfunction
... [138] Tg6074 mice overproduce TNF and C57/BL6 mice Overexpression of TNF Cognitive testing: Open field Test Passive avoidance Test Hot plate Test Kyphosis, ataxia, seizures, poor learnin[r] ...
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The leaves of Crataeva nurvala Buch Ham modulate locomotor and anxiety behaviors possibly through GABAergic system
... hole-cross test (HCT), open field test (OFT), and rota-rod test (RRT) to evaluate sedative properties, where anxiolytic activities were investigated using elevated plus maze (EPM), ...
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Effect of Marrubium vulgare L. Aerial Parts Aqueous and Ethanolic Extracts on Morphine Withdrawal Syndrome in Mice
... The effect of intraperitoneal injection of aqueous and ethanolic extracts of Marrubium vulgare L. (0.1, 0.5, 1.5, 2.5 g/kg) is studied on morphine withdrawal syndrome in mice. Dependence was induced using subcutaneous ...
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What Do We Know About Technical Assistance? Enhancing the Science and Practice of Technical Assistance via a Research Synthesis
... The current studies support previous literature indicating that amphetamine increases locomotor activity acutely (Dandiya & Kulkarni, 1974), and that this activity becomes sensitized chronically (Lynch, Kennny, & ...
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Effects of intravenous immunoglobulin therapy on behavior deficits and functions in sepsis model
... behavior [8]. Rearing and grooming events dramatically decreased in animals in the CLP group, which indicated attenuation in the locomotor activity by the induction of sepsis. The activity was attenuated on day 10 and ...
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EVALUATION OF ANXIOLYTIC POTENTIAL OF ETHANOLIC EXTRACT HYPERICUM HOOKERIANUM IN STRESS INDUCED SWISS ALBINO MICE
... (EPM) test, Open Field Test (OFT), Hole Board Test (HBT), Light dark exploration Test (LDE) in restraint stress induced ...Behavioral test parameters for anxiety were ...
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EFFECT OF METHANOLIC EXTRACT OF ALSTONIA SCHOLARIS LEAVES AGAINST AGGRESSION IN MICE, AND ITS ACUTE TOXICITY PROFILE
... different test models such as Isolation-induced aggression, Resident-intruder aggression, Open field test and Water competition test were carried ...
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