Open label
The Ethics of Open-Label Placebos in Pediatrics
... for open-label placebos to help reduce pediatric drug loads, particularly in conditions with strong psychosocial components like ADHD, abdominal pain, and migraine, should be ...
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Rapid Visible Improvements in Onychomycosis: An Open Label Clinical Investigation of Kerasal NailTM
... An open-label, single-arm baseline-controlled 4-week post-marketing clinical investigation to evaluate the ability of Kerasal Nail to provide rapid improve- ments in nail appearance in patients with ...
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Safety of long-term use of linezolid: results of an open-label study
... multicenter, open-label, pilot study was conducted at six recruiting centers in the US and three centers in Europe between 17 November, 2008, and 27 December ...
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IGF-1 in autosomal dominant cerebellar ataxia - open-label trial
... Results: A total of 19 molecularly confirmed patients with SCA3, 1 patient with SCA6 and 6 patients with SCA7 completed our study. They were 8 females and 18 males, 28 to 74 years of age (average ± SD: 49.3 ± 14.1). ...
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OnabotulinumtoxinA injections for atypical odontalgia: an open-label study on nine patients
... prospective, open-label, non-controlled study on a consecutive cohort of patients with a diagnosis of AO treated via local injection of OnabotA at the Headache Unit of the Hospital Clínico San Carlos ...
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A prospective, open label, 24 week trial of methylcobalamin in the treatment of diabetic polyneuropathy
... prospective, open-label study on adult diabetic subjects with polyneuropathy who were given 1500 μgm/day of oral methylcobalamin over ...24-week open label study demonstrated that symptoms of ...
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Treatment of mucocutaneous manifestations in Behçet’s disease with anakinra: a pilot open label study
... Two of six patients met the primary outcome of complete remission by month 6 (Table 1). Two patients met the criteria for partial response. Two patients were considered treatment failures. One patient terminated the ...
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Ginkgo biloba for the treatment of vitilgo vulgaris: an open label pilot clinical trial
... Background: Vitiligo is a common hypopigmentation disorder with significant psychological impact if occurring before adulthood. A pilot clinical trial to determine the feasibility of an RCT was conducted and is reported ...
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Olmesartan for non alcoholic steatohepatitis complicated with hypertension: An open label study
... prospective open-label study was conducted in patients with biopsy-proven NASH, and who were recruited from the Kitasato University East Hospital, Sagamihara, Kana- gawa, ...
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Treatment of alcohol dependence with low dose topiramate: an open label controlled study
... present open-label controlled study was to assess the efficacy and tolerability profile of low- dose topiramate as adjunctive treatment in alcohol depen- dence during the immediate post-detoxification ...
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EVALUATION OF ANTIUROLITHIC HERBAL FORMULA FOR UROLITHIASIS: A RANDOMIZED OPEN LABEL CLINICAL STUDY
... This study was conducted at medicinal plant and traditional medicine research and development center (B2P2TOOT), Ministry of Health, Indonesia. The study was carried out by 70 physicians and 20 pharmacists who had been ...
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Approaches to discontinuing efalizumab: an open-label study of therapies for managing inflammatory recurrence
... This was an open-label, investigational study carried out in nine centres on patients with moderate-to-severe plaque psoriasis. The study was carried out according to Good Clinical Practice guidelines and ...
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An Open Label Pilot Study of Kalyanaka Ghrita in the Management of Obsessive Compulsive Disorder
... An open label pilot study of kalyanaka ghrita in the management of obsessive compulsive disorder... Kalyanaka ghrita contains 28 ingredients (herbs), and it is indicated in grahonmada[r] ...
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Vasoclear in the Remedial of Cardio Vascular Problems by Natural Means: An Open Label Study
... an open label, two centered trial wherein eligible patients were enrolled post consenting to participate in the study on an institutional ethics committee approved informed consent ...
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An Open-Label Study of Lamotrigine Adjunct or Monotherapy for the Treatment of Adolescents With Bipolar Depression
... This was an 8-week open-label trial of lamotrigine monotherapy or adjunct therapy in adolescents with bipolar depression or mixed mania. Informed written and verbal consent was obtained from the parent or ...
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Impact of tiotropium + olodaterol on physical functioning in COPD: results of an open-label observational study
... The findings of this study should be viewed in light of its limitations. This was an open-label, nonrandomized study using an observational design over a short period of time. The measures of physical ...
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Disease activity and cognition in rheumatoid arthritis: an open label pilot study
... This was an open-label pilot study. Cerebral MRI scans, fatigue scores, 28-joint disease activity score (DAS28), and psychometric assessment were performed on patients before, and 12 weeks into, anti-TNF ...
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Dupilumab in adolescents with uncontrolled moderate‐to‐severe atopic dermatitis : results from a phase IIa open‐label trial and subsequent phase III open‐label extension
... high rates of atopic/allergic comorbidities in both adolescent patient populations, support the underlying role of IL-4/IL- 13-driven type 2 inflammation in these diseases. Although the safety and efficacy results are ...
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Xenon in the treatment of panic disorder: an open label study
... This investigator-initiated study was performed under a prospective clinical trial protocol approved by the Institute of Mental Health and Addictology, which is accredited by the Ministry of Health of the Russian Fed- ...
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Duloxetine in the treatment of major depressive disorder: an open label study
... The efficacy of duloxetine (40–120 mg/d) in the acute treatment of MDD has been established in a number of acute phase, double-blind, placebo-controlled studies, in addition to a long-term open-label study ...
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