Open label study
Duloxetine in the treatment of major depressive disorder: an open label study
... long-term open-label study ...this study are consistent with those obtained previously at a 60 mg once daily dose [9,10], although double-blind, placebo-controlled studies should be regarded ...
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Rationale and design of the VISION study: a randomized, open-label study to evaluate the long-term safety of vonoprazan as maintenance treatment in patients with erosive esophagitis
... 5-year, open-label study has a planned recruitment of 195 participants (2:1 allocation vonoprazan:lansoprazole) from 33 sites in ...The study comprises an 8-week “healing” phase (vonoprazan 20 ...
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An open-label study of algorithm-based treatment versus treatment-as-usual for patients with schizophrenia
... multisite, open-label study of ALGO in ...The study was approved by the institutional review board at each participating site, and written informed consent was obtained from all patients after ...
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Olmesartan for non alcoholic steatohepatitis complicated with hypertension: An open label study
... prospective open-label study was conducted in patients with biopsy-proven NASH, and who were recruited from the Kitasato University East Hospital, Sagamihara, Kana- gawa, ...the study, all ...
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<p>Apatinib Plus Temozolomide for Recurrent Glioblastoma: An Uncontrolled, Open-Label Study</p>
... clinical study showed rela- tively satisfactory results and met our ...clinical study, patients who failed treat- ment with apatinib had particularly rapid tumor recurrence and more diffused cerebral ...
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Safety of long-term use of linezolid: results of an open-label study
... for study enrollment were $18 years old, required long-term antibiotic therapy, and had received linezolid 600 mg every 12 hours for 6 weeks or longer and were currently on drug (or had received linezolid for 6 ...
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Effect of verapamil on systemic exposure and safety of umeclidinium and vilanterol: a randomized and open-label study
... Three subjects had AEs that led to withdrawal from the study (Table 1). All were considered possibly treatment- related and resolved following treatment discontinuation. One subject was withdrawn on Day 4 of UMEC ...
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OnabotulinumtoxinA injections for atypical odontalgia: an open-label study on nine patients
... Our study suggests that local injections of OnabotA may be an effective and safe therapeutic option for the treatment of AO. Nonetheless, further RCTs are needed to corroborate these findings with a greater level ...
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Approaches to discontinuing efalizumab: an open-label study of therapies for managing inflammatory recurrence
... an open-label, investigational study carried out in nine centres on patients with moderate-to-severe plaque ...The study was carried out according to Good Clinical Practice guidelines and the ...
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Treatment of mucocutaneous manifestations in Behçet’s disease with anakinra: a pilot open label study
... International Study Group Criteria were eligible for ...single-center study conducted at the National Institutes of Health (Bethesda, MD, ...by study staff from an observational cohort of pa- tients ...
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Vasoclear in the Remedial of Cardio Vascular Problems by Natural Means: An Open Label Study
... the study participants (Fig 1 and ...with study supplement was reviewed at each visit by examination of the returned used ...this study was not randomized controlled trial, also as Vasoclear is ...
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Xenon in the treatment of panic disorder: an open label study
... Xenon therapy was generally well tolerated, side effects, mainly headache and dizziness, were rare and lead to only 5 patients dropping out from the study (5.8%). After carefully reviewing the data from these ...
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Open-label study of the short-term effects of memantine on FDG-PET in frontotemporal dementia
... the study, early with- drawals occurred prior to start of ...with study completers with respect to their demographic data using Chi-squared tests and independent- samples ...the study early showed no ...
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Agomelatine as monotherapy for major depression: an outpatient, open-label study
... This study has several limitations. An open-label, non- randomized design could be associated with various sources of ...the study but refused it for whatever reason was not part of the ...
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Ivacaftor treatment in patients with cystic fibrosis and the G551D-CFTR mutation
... ABSTRACT: Cystic fibrosis (CF) is an autosomal recessive lethal disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that encodes for CFTR, an epithelial cell-surface ...
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Gabapentin adjunctive to risperidone or olanzapine in partially responsive schizophrenia: an open-label pilot study
... or open studies to date that have examined the efficacy and toler- ability of gabapentin as an adjunctive to novel antipsychotics in the treatment of partially responsive ...pilot open-label ...
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An Open Label Pilot Study of Kalyanaka Ghrita in the Management of Obsessive Compulsive Disorder
... present study. In present study it has been found that most of the patients have responded positively in short course of treatment (60 days) and the positive effect continued even after stopping the ...
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Impact of tiotropium + olodaterol on physical functioning in COPD: results of an open-label observational study
... the initiation of treatment (treatment-emergent AEs). In total, 59 patients (3.2%) had AEs that led to discontinuation of treatment. Infections and infestations (37 patients, 2.0%) and respiratory, thoracic, and ...
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An open label pilot study on preventing glucocorticoid induced diabetes mellitus with linagliptin
... Incretin-related drugs, such as dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists, lower blood glucose in patients with type 2 diabetes through a transient glucose-dependent ...
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Treatment of alcohol dependence with low dose topiramate: an open label controlled study
... present study are: a) the relatively small sample size, which reduces the statistical significance of our findings, b) the study did not follow a double-blind placebo control design; such a design was not ...
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