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oral clefts

Whole Exome Sequencing of Distant Relatives in Multiplex Families Implicates Rare Variants in Candidate Genes for Oral Clefts

Whole Exome Sequencing of Distant Relatives in Multiplex Families Implicates Rare Variants in Candidate Genes for Oral Clefts

... for oral clefts in human association and linkage studies, and animal models argue even more genes may be ...to oral clefts, which have a complex and heterogeneous ...

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Oral clefts with associated anomalies: findings in the Hungarian Congenital Abnormality Registry

Oral clefts with associated anomalies: findings in the Hungarian Congenital Abnormality Registry

... It has been known for more than 80 years that cleft lip with or without cleft palate (CL/P) and isolated cleft pal- ate (CP), collectively termed oral clefts (OCs), are fre- quently associated with ...

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Influence of Ethnicity on the Incidence Rate of Oral Clefts in Northern Iran

Influence of Ethnicity on the Incidence Rate of Oral Clefts in Northern Iran

... In the present study, 38.8% newborns with oral clefts were born to consanguineous parents. While in our previous study (17) this rate was low. In addition, in Saudi Arabia, parental consanguineous marriage ...

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Testing reported associations of genetic risk factors for oral clefts in a large Irish study population

Testing reported associations of genetic risk factors for oral clefts in a large Irish study population

... An advantage of our study was the large number of CLP and CP cases and parents available from an ethnically homogenous study population. A limitation of our study was that only one or a few SNPs were tested in each gene. ...

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Non-syndromic oral clefts and risk of cancer: a systematic review

Non-syndromic oral clefts and risk of cancer: a systematic review

... of oral clefts, which sets a limitation to ind out such ...orofacial clefts and ultimately to predict its occurrence and to facilitate ge- netic counseling of affected families ...

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Health-Related Quality of Life Among Preadolescent Children With Oral Clefts: The Mother's Perspective

Health-Related Quality of Life Among Preadolescent Children With Oral Clefts: The Mother's Perspective

... The use of parent interviews for this data collection means, by definition, that these results reflect parental perception, which is 1 important yet specific outcome of cleft care. There is obviously important ...

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The effects of oral clefts on hospital use throughout the lifespan

The effects of oral clefts on hospital use throughout the lifespan

... oral clefts. In order to capture changes in hospitalization risks due to oral clefts over age, we model hospitalizations during several age groups that are feasible with the available data ...

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The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts

The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts

... The study intervention population included a consecutive series of in-hospital live-born infants with any form of isolated or associated typical CL/P, between January 1, 2003 and December 31, 2005 in 47 hospitals in ...

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Lack of association between IRF6 polymorphisms and nonsyndromic oral clefts in South Indian population

Lack of association between IRF6 polymorphisms and nonsyndromic oral clefts in South Indian population

... clinicians. Oral clefts with other congenital malfor‐ mations or major developmental disorders were excluded from the ...nonsyndromic oral clefts and were classified into two groups: cleft lip ...

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Academic Achievement of Children and Adolescents With Oral Clefts

Academic Achievement of Children and Adolescents With Oral Clefts

... achievement in each grade as the unit of the analysis. To improve generalizability and data quality, we dropped kinder- garten, grade 1, and grade 12, because these grades had limited testing of stu- dents. We also ...

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Laterality of Oral Clefts and Academic Achievement

Laterality of Oral Clefts and Academic Achievement

... both oral clefts and hemispheric dominance are associated may help explain these ...right-sided clefts because of the assumption that they may be at greater risk of developmental ...

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Maternal occupational exposure and oral clefts in offspring

Maternal occupational exposure and oral clefts in offspring

... In our study we found no association between mater- nal occupational exposure to solvents and oral clefts in the main analyses. However, in the additional analyses an association is found between maternal ...

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Reduction in non syndromic oral clefts following mandatory flour fortification with folic acid in Northern Iran

Reduction in non syndromic oral clefts following mandatory flour fortification with folic acid in Northern Iran

... Methods: In this hospital based study from March 2006 to September 2009, we screened the total number of live births at all hospitals in Golestan province in North of Iran, as well as th[r] ...

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Determinants of health-related and oral health-related quality of life in adults with orofacial clefts: a cross-sectional study

Determinants of health-related and oral health-related quality of life in adults with orofacial clefts: a cross-sectional study

... A list of all persons with oral clefts registered at the referral center for patients with congenital malformations in 2013 Manaus was obtained. Adults aged 18 years or more were initially contacted by ...

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Systematic Review and Meta-analyses: Fever in Pregnancy and Health Impacts in the Offspring

Systematic Review and Meta-analyses: Fever in Pregnancy and Health Impacts in the Offspring

... Our review shows that the available literature supports the occurrence of adverse health impacts in association with fever. The strongest evidence is available for effects on the following selected birth defects: neural ...

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Systematic Review and Meta-analyses: Fever in Pregnancy and Health Impacts in the Offspring

Systematic Review and Meta-analyses: Fever in Pregnancy and Health Impacts in the Offspring

... RESULTS: The available literature supported an increased risk of ad- verse offspring health in association with fever during pregnancy. The strongest evidence was available for neural tube defects, congenital heart ...

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Facial morphometrics of children with non-syndromic orofacial clefts in Tanzania

Facial morphometrics of children with non-syndromic orofacial clefts in Tanzania

... aged 4 to 120 months. The mean age of the CL/P group was 29.4 ± 31.8 months and the mean age of the control group was 54.1 ± 34.5 months, the difference largely result- ing from a greater number of infants in the CL/P ...

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Neurodevelopmental and Academic Outcomes in Children With Orofacial Clefts: A Systematic Review

Neurodevelopmental and Academic Outcomes in Children With Orofacial Clefts: A Systematic Review

... reading scores of children aged 7 to 9 revealed a strong association between memory deficits and reading disability, reporting that 61% of children with memory de fi cits and clefts had reading disabilities compared ...

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Dose-dependent Effect of Folic Acid on the Prevention of Orofacial Clefts

Dose-dependent Effect of Folic Acid on the Prevention of Orofacial Clefts

... orofacial clefts. A similar prevention of orofacial clefts requires a high dose of folic ...orofacial clefts is caused by the folic acid supplementation (ie, causal effect) or may be connected with ...

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Subsequent Vertebral Fractures after Vertebroplasty: Association with Intraosseous Clefts

Subsequent Vertebral Fractures after Vertebroplasty: Association with Intraosseous Clefts

... with clefts observed in this study results from ab- normal biomechanics or simply reflects the nature of the un- derlying pathologic ...intraosseous clefts are a marker for aggressive osteoporosis with high ...

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