Oral dysplasia
Development of tissue-engineered models of oral dysplasia and early invasive oral squamous cell carcinoma
... mimic oral dysplasia or cancer (Nystrom et al, 2005; Costea et al, 2006; Vigneswaran et al, 2006; Gaballah et al, 2008; Marsh et al, ...investigate oral dysplasia and invasive carcinoma may ...
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Feasibility of recruitment to an oral dysplasia trial in the United Kingdom
... in oral leukoplakia failed to show any of them having a benefit over placebo in OED ...in oral premalignant ...both oral dysplasia and cancer along with other malignancies of the gastrointes- ...
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Immunohistochemical evalution of bcl-2 oncoprotein in oral dysplasia and carcinoma
... epithelial dysplasia and varying grades of oral ...epithelial dysplasia and in peripheral cells of the islands of differentiating squamous cell ...
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Gene expression profiling identifies genes predictive of oral squamous cell carcinoma
... OSCC, oral dysplasia, and clinically normal oral tissue from surgical patients without head and neck cancer or pre-neoplastic oral lesions (controls), using Affymetrix U133 ...
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The clinical determinants of malignant transformation in oral epithelial dysplasia
... Methods: We recruited patients with a histopathological diagnosis of OED to a longitudinal observational cohort study in a tertiary oral dysplasia clinic. Clinical, histopathological and risk factor data ...
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Evaluation of caveolin-1 expression in different grades of oral epithelial dysplasia
... Immunohistologic technique and using mononuclear antibodies against specific markers of dysplastic cells can provide useful information regarding malignant transformation. The percentage of positive results correlates ...
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Stimuli-disassembling gold nanoclusters for diagnosis of early stage oral cancer by optical coherence tomography
... in oral dysplasia ...the oral dys- plastic tissue than in normal tissue ...the dysplasia (increased red pixels as compared to the base case in ...
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The clinical determinants of malignant transformation in oral epithelial dysplasia
... tertiary oral dysplasia clinic with lesions clinically suspicious of OED were prospectively recruited into a clinical and molecular biomarker study since September 1999 and their demographic and pathology ...
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Histomorphometric Analysis of oral Epithelial Dysplasia and oral Squamous Cell Carcinoma
... Dental College and Hospital. All the slides will be reviewed by the senior pathologist. SAMPLE SIZE: Group- A (n=200) Oral Squamous cell carcinoma Group – B (n=200) Oral Dysplasia. Total number of ...
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Cyclin D1 and P27KIP1: The Gatekeepers of Dysplasia
... in oral squamous cell carcinoma and leukoplakia. J Korean Assoc Oral Maxillofac ...of oral dysplasia and squamous cell carcinoma differentiation. Oral Surgery, Oral Medicine, ...
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Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trials
... of oral dysplasia varied from ...of oral dysplasia was more valid and reproducible for severe dysplasia and malignancy than it was for low grade ...of dysplasia and all have ...
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p16 promoter methylation is a potential predictor of malignant transformation in oral epithelial dysplasia
... Management of the patient with oral epithelial dysplasia depends on the ability to predict malignant transformation. Histological grading of this condition fails in this regard and is also subject to inter ...
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Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq
... normal oral samples, 17 oral dysplasias and 167 oral carcinomas (HPV status not indicated) from different individuals ...with oral dysplasia, of which 35 developed oral cancer ...
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... Normal oral mucosal keratinocytes unitedly with various epithelial cell lines expressed c-met protein which substantiated that normal oral epithelial cells have the machinery to react to Scatter ...normal ...
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Angiogenic squamous dysplasia-like phenomenon in oral epithelial precursor lesions
... Bronchial dysplasias are believed to be the direct pre- cursors of squamous cell carcinoma of the lung. Re- cently, a distinct qualitative form of angiogenesis termed ‘angiogenic squamous dysplasia’ was identified ...
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Immunohistochemical expression of p53 and Bcl2 in varying grades of Oral Epithelial Dysplasia
... of oral squamous cell carcinoma was taken as a positive control for expression of p53 and for Bcl2 normal human lymph node served as a positive control whereas negative control was an immunohistochemically stained ...
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Malignant transformation in 5071 southern Taiwanese patients with potentially malignant oral mucosal disorders
... malignant oral epithelial lesions would actually progress to develop oral cancer, periodical follow-up assessments were arranged for all patients with a frequency based on the clinical features and the need ...
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... After obtaining the biopsy specimen & exfoliative cytology specimen, various patients were treated in accordance with their lesions. All the patients were advised to quit the habit of tobacco consumption and areca ...
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... The present study was conducted to evaluate the importance of AgNORs in differentiating benign, pre-malignant and malignant lesions of the oral cavity. The neoplastic cells generally exhibit a rise in the ...
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... normal oral mucosa through the different degrees of dysplasia to frank invasive carcinoma ...epithelial dysplasia for the nutrition and growth of the dysplastic ...
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