organ injury
Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis
... to organ injury ...sepsis-induced organ injury through reduction of oxidative stress and ...sepsis-induced organ injury, kallistatin gene delivery or kallistatin protein ...
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A Mechanism for Inhaled Anesthetic Induced Solid Organ Injury: Inflammation
... Background: Inhaled anesthetics, including halothane, iso- and sevoflurane induce proinflamma- tory cytokine release. Halothane is an inhaled anesthetic agent that is metabolized by the liver in- to a highly reactive ...
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Angiography and embolisation for solid abdominal organ injury in adults - a current perspective
... Over the past twenty years there has been a shift towards non-operative management (NOM) for haemodynami- cally stable patients with abdominal trauma. Embolisation can achieve haemostasis and salvage organs without the ...
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Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic Shock
... multiple organ failure (MOF); however, a direct inhibitor of I κ B kinase (IKK), which plays a pivotal role in the activation of NF- κ B, has not been investigated in ...for organ injury and ...
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Radiation: a poly-traumatic hit leading to multi-organ injury
... traumatic injury as well. Radiation injury is defined as an ionizing radiation exposure inducing a series of organ injury within a specified ...of organ injury depends on the ...
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Acute organ injury is associated with alterations in the cell-free plasma transcriptome
... that organ injury is associated with unique transcriptome ...ischemia-reperfusion injury and renal ischemia-reperfusion ...renal injury (crucial to a sensitive diagnostic) and (2) to establish ...
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Human Ghrelin Ameliorates Organ Injury and Improves Survival after Radiation Injury Combined with Severe Sepsis
... sepsis-induced organ injury and mortality after radiation ...attenuates organ injury and improves survival in a rat model of radiation combined injury (RCI) and, if so, the potential ...
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Acute exacerbation of IPF has systemic consequences with multiple organ injury, with SRA+ and TNF-α+ cells in the systemic circulation playing central roles in multiple organ injury
... multiple organ injury in our cases begin with a rapid and substantial release of cytokines into the systemic circulation by activated macrophages causing an imbalance between pro- and anti-inflammatory ...
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Spectrum of abdominal organ injury in a primary blast type
... visceral injury in primary blast injury in our setting is restricted as a lack of easy availability of advanced imag- ing techniques and intensive care unit, sophisticated resuscitation measures and the ...
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NonOperative Management of Blunt Solid Abdominal Organ Injury in Calabar, Nigeria
... Background: Over the past several years, non-operative management has been increasingly recommended for the care of selected blunt abdominal trauma patients with solid organ injuries. Objective: To evaluate the ...
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Reparative T lymphocytes in organ injury
... specific organ involvement, the underlying cause and stage of organ injury ...injured organ), and mechanisms to modulate their pro-repair T cell lineage commitment via epigenetic and metabolic ...
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Combined Administration of Human Ghrelin and Human Growth Hormone Attenuates Organ Injury and Improves Survival in Aged Septic Rats
... When given to aged animals with endotoxin-induced sepsis, rat ghrelin’s activity in attenuating proinflammatory cytokine production and organ injury is diminished (19). In contrast to young animals, ...
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A monoclonal antibody to the adherence promoting leukocyte glycoprotein, CD18, reduces organ injury and improves survival from hemorrhagic shock and resuscitation in rabbits
... Leukocytes have been shown to play an important role in the development of isolated organ injury after experimental ischemia and reperfusion. To examine the role of leukocytes in generalized ...
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Potential Pathogenesis of Multiple Organ Injury in COVID-19
... Built on the published literature, we summarized the data of ARDS and AKI caused by COVID-19 and found that the number of ARDS caused by COVID-19 far exceeded that of AKI. According to the distribution of ACE2 in tissues ...
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Hypoxia inducible factors and the prevention of acute organ injury
... sublethal injury that are believed to participate in tissue tolerance during subsequent ...acute injury in various organ systems, including neuronal, retinal, cardiac, renal, and hepatic ...
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The value of serum procalcitonin content for assessing the inflammation and organ injury in neonatal septicemia
... heart injury, and it is of great value for judgment of disease severity, establishment of treatment solution and other ...heart injury is mainly discussed in the study, and the value of PCT content for ...
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AICAR Attenuates Organ Injury and Inflammatory Response after Intestinal Ischemia and Reperfusion
... Gut injury was scored as described previously ...lung injury was used based on previ- ously described (22) histological ...The injury was graded as absent, mild, moderate or severe with a score of 0 ...
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Angiotensin (1–7) attenuates organ injury and mortality in rats with polymicrobial sepsis
... A previous study showed that pretreatment of 1 mg/kg Ang-(1–7) inhibited LPS-induced cytokine production and hypothermia and thereby protected mice from the fatal consequences of endotoxemia [15]. In the present study, 1 ...
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Long term remote organ consequences following acute kidney injury
... distant organ injury [24, ...other organ-systems would be induced by the disturbed cytokine/chemokine homeostasis in AKI, which may be attributable to the decreased renal clearance and/or increased ...
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The treatment of spleen injuries: a retrospective study
... The splenic injuries were classified retrospectively according to AIS and Organ Injury Scale (OIS) [8, 9]. The injuries of patients splenectomized without a preoperative CT-scan were also classified ...
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