Orientia tsutsugamushi
Molecular epidemiology of Orientia tsutsugamushi in chiggers and ticks from domestic rodents in Shandong, northern China
... by Orientia tsutsugamushi, which is transmitted by larval-stage trombi- culid ...O. tsutsugamushi is a Gram- negative obligate intracellular bacterium categorized in the genus Orientia within ...
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Association of High Orientia tsutsugamushi DNA Loads with Disease of Greater Severity in Adults with Scrub Typhus
... Orientia tsutsugamushi, the cause of scrub typhus, is a major pathogen in the Asia-Pacific ...O. tsutsugamushi loads in the blood samples of patients with scrub typhus on the day of hospital ...
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Lack of Effect of Dexamethasone on Growth of Orientia Tsutsugamushi Gilliam in Mouse L929 Cells
... Anti-Orientia tsutsugamushi Gilliam mouse serum was ob- tained by injecting C3H mice 2-3 times with rickettsia at 2-week intervals and sampling after 4 ...anti- Orientia tsutsugamushi Gilliam ...
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Evaluation of an Immunoglobulin M Capture Enzyme-Linked Immunosorbent Assay for Diagnosis of Orientia tsutsugamushi Infection
... by Orientia tsutsugamushi, has become an important acute febrile illness in the Korea, Japan, and elsewhere in the Asia-Pacific region (4, 17, 20, ...
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An ELISA assay using a combination of recombinant proteins from multiple strains of Orientia tsutsugamushi offers an accurate diagnosis for scrub typhus
... Early detection, accurate diagnosis, and timely treat- ment of rickettsial disease are imperative to improve disease outcome during outbreaks. Scrub typhus (ST) is one of the most common rickettsial diseases caused by ...
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Detection of Antibodies against Orientia tsutsugamushi Sca Proteins in Scrub Typhus Patients and Genetic Variation of sca Genes of Different Strains
... by Orientia tsutsugamushi infection, is one of the main causes of acute febrile illness in the Asian-Pacific ...O. tsutsugamushi surface cell antigen (sca) family genes en- coding autotransporter ...
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Expression and Refolding of Truncated Recombinant Major Outer Membrane Protein Antigen (r56) of Orientia tsutsugamushi and Its Use in Enzyme-Linked Immunosorbent Assays
... of Orientia tsutsugamushi is the immunodominant antigen in human scrub typhus ...O. tsutsugamushi by immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA) for reactivity with rabbit sera ...
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Genotype Diversity and Distribution of Orientia tsutsugamushi Causing Scrub Typhus in Thailand
... O. tsutsugamushi sequences listed in ...O. tsutsugamushi sequences retrieved from ...of Orientia tsutsugamushi based on partial 56-kDa TSA gene sequences demonstrating the relationships among ...
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High Rates of Homologous Recombination in the Mite Endosymbiont and Opportunistic Human Pathogen Orientia tsutsugamushi
... Orientia tsutsugamushi is an intracellular a-proteobacterium which resides in trombiculid mites, and is the causative agent of scrub typhus in East ...O. tsutsugamushi population was both highly ...
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Prospective Evaluation of Commercial Antibody-Based Rapid Tests in Combination with a Loop-Mediated Isothermal Amplification PCR Assay for Detection of Orientia tsutsugamushi during the Acute Phase of Scrub Typhus Infection
... S crub typhus, caused by Orientia tsutsugamushi, is an impor- tant acute febrile illness in the Asia-Pacific region and is en- demic in Thailand and Laos (10, 12). The clinical discrimination of scrub ...
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Prevalence of antibodies against Ehrlichia spp and Orientia tsutsugamushi in small mammals around harbors in Taiwan
... tia tsutsugamushi, the etiological agent of scrub typhus, have been isolated from humans and its vectors, larval- stage trombiculid mites (chiggers) [3, ...O. tsutsugamushi infections in wild rodents, ...
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Outer Membrane Protein A Conservation among Orientia tsutsugamushi Isolates Suggests Its Potential as a Protective Antigen and Diagnostic Target
... tsutsugamushi strain OmpA nucleotide and translated protein sequences.. 140.[r] ...
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Development of a Recombinant Protein-Based Enzyme-Linked Immunosorbent Assay and Its Applications in Field Surveillance of Rodent Mice for Presence of Immunoglobulin G against Orientia tsutsugamushi
... Cutoff value for ELISA. Background reactivity and possible cross-reactivity were assessed by analyzing preimmune serum specimens from healthy rabbits, mice, and rats. The cutoff values were set at ODn ⫹ 3 standard ...
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Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka
... This is the first study from Sri Lanka to describe the genotypes of OT, in two geographical areas that are about 100 km apart along the western coastal belt within the wet zone of Sri Lanka with probably similar eco- ...
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Use of Multiplex Real Time PCR To Diagnose Scrub Typhus
... by Orientia tsutsugamushi, is a common cause of acute undifferentiated febrile illness in the Asia-Pacific ...O. tsutsugamushi 47-kDa, groEL, and human interferon beta (IFN-  gene) genes to improve ...
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The saga of scrub typhus with a note on the outbreaks in Mizoram
... by Orientia tsutsugamushi, it is transmitted through the bite of mites belonging to the genus Leptotrombidium, in which the bacteria are obligate ...as tsutsugamushi (insect disease), human infection ...
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Isolation of a Novel Orientia Species (O chuto sp nov ) from a Patient Infected in Dubai
... eschar. Orientia tsutsugamushi serology demonstrated a 4-fold rise in antibody titers in paired serum collections (1:512 to 1:8,192), with the sera reacting strongest against the Gilliam strain ...An ...
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Identification and Characterization of Orientia chuto in Trombiculid Chigger Mites Collected from Wild Rodents in Kenya
... time, Orientia tsutsugamushi was the only member of the genus Orientia, until 2010, when a new species, Orientia chuto, was identified in Australia in a patient who contracted scrub typhus in ...
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A Concise Review of the Epidemiology and Diagnostics of Rickettsioses: Rickettsia and Orientia spp
... Rickettsia tsutsugamushi was renamed Orientia tsutsugamushi; this genus (Orientia) was geneti- cally distinct enough but is still closely related to Rickettsia and remains in the same ␣ -1 ...
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Early Diagnosis of Scrub Typhus with a Rapid Flow Assay Using Recombinant Major Outer Membrane Protein Antigen (r56) ofOrientia tsutsugamushi
... O. tsutsugamushi (12, 20, 21, 28) which comprises 10 to 15% of the total rickettsial cellular protein content (15, ...O. tsutsugamushi depend largely on variations in the 56-kDa antigen (27, ...
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