Ovarian Granulosa Cell
Clinicopathological characteristics and prognosis of adult ovarian granulosa cell tumor: a single-institution experience in China
... Ovarian granulosa cell tumor (GCT) is a rare ovarian neoplasm derived from ovarian sex-cord stromal cells in the ...adult granulosa cell tumor (AGCT) and juvenile ...
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Luteinizing hormone elevation in ovarian granulosa cell tumor: a case report and review of the literature
... Background: Ovarian granulosa cell tumors (GCTs) are the most common type of potentially malignant ovarian sex cord-stromal tumor. GCTs often produce estrogen and/or progesterone; ...
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MR findings of primary ovarian granulosa cell tumor with focus on the differentiation with other ovarian sex cord-stromal tumors
... confirmed ovarian granulosa cell tumor were retrospectively reviewed by two radiologists with consensus ...20 ovarian granulosa cell tumors were detected on ...
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Ovarian granulosa cell tumors: a retrospective study of 27 cases and a review of the literature
... recurrent ovarian granulosa cell tumors: Ki67 – 1 and p53 immunohistochemistry demonstrates a possible molecular basis for the poor histopathologic prediction of clinical ...
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Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat
... Case summary A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the ...
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Collision tumor of the colon – colonic adenocarcinoma and ovarian granulosa cell tumor
... an ovarian granulosa cell ...rent ovarian carcinoma or a complicated pelvic abscess was also offered as a radiological differential ...
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Diagnostic relevance of urinary steroid profiles on ovarian granulosa cell tumors: two case reports
... of ovarian granulosa cell tumor; therefore, we concluded that a urinary steroid profile could be a more effective method to follow-up such patients compared to the traditional serum hormones ...
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Single tertiary care centre experience of ovarian granulosa cell tumour in Chennai, India: a retrospective analysis
... in granulosa cell tumour. Since the majority of granulosa cell tumours are confined to one ovary at diagnosis, surgery followed by observation is an acceptable ...
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The molecular mechanism of ovarian granulosa cell tumors
... GCT incidence of ovarian cancer accounts for about 2% to 5%, while the prognosis is usually better. Five-year survival rate is up to 90%. High recurrent rate is the most critical factor for GCT death. At present, ...
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MicroRNA profiling of ovarian granulosa cell tumours reveals novel diagnostic and prognostic markers
... GCTs are believed to arise from granulosa cells that surround the oocyte in the developing follicle [1]. How- ever, despite their common cellular origin, the two sub- types appear to exhibit very distinct ...
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Original Article MicroRNA-182 inhibits rat ovarian granulosa cell apoptosis by targeting Smad7 in polycystic ovarian syndrome
... of granulosa cells may contribute to the aberrant folliculogenesis observed in polycystic ovary syndrome ...including cell dif- ferentiation and ...in granulosa cell ...in granulosa ...
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Original Article Cytochrome P450 family proteins as potential biomarkers for ovarian granulosa cell damage in mice with premature ovarian failure
... IP cell lysate (Beyotime Bio- ...IP cell lysate (Beyotime Biotechnology, Hang Zhou, China), incubated in a 100°C water bath for 15 minutes and centri- fuged at 12000 r/min for 10 ...
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Quercetin increases the antioxidant capacity of the ovary in menopausal rats and in ovarian granulosa cell culture in vitro
... HE staining results showed that the ovaries of meno- pausal rats demonstrated obvious aging characteristics, including the exhaustion of the resting follicle reserve and a marked increase in the proportion of ...
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Bilateral granulosa cell tumors: a novel malignant manifestation of multiple endocrine neoplasia 1 syndrome found in a patient with a rare menin in-frame deletion
... bilateral ovarian granulosa cell tumors diagnosed in our patient with florid MEN1 syndrome due to a rare intronic mutation of the MEN1 gene ...bilateral granulosa cell malignancy, and ...
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BMI1 Deficiency Results in Female Infertility by Activating p16/p19 Signaling and Increasing Oxidative Stress
... of granulosa cells by activating p16/p19 signaling pathways in ...of ovarian sections from 7-week old mice stained immunohistochemically for PCNA and ...proliferating cell nuclear antigen; Bcl-2, ...
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BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2
... to alter expression of a number of genes (ID2, BMPR2, SMAD1, SMAD7 and GREM2, and possibly also LGR5) expressed by ovarian somatic cells. GREM1 was able to prevent both stimulatory (ID2, GREM2) and inhibitory ...
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A possible role for AMP-activated protein kinase activated by metformin and AICAR in human granulosa cells
... (IgG; Cell Sig- naling Technology), and human glyceraldehyde-3- phosphate dehydrogenase (GAPDH) antibody, mouse monoclonal immunoglobulin G (IgG, Ambion Austin, TX)] in TBS containing 5% BSA at ...
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The Association of Gender, Age, and Coping with Internalizing Symptoms in Youth with Sickle Cell Disease
... Whereas the full-length protein was detected in transfected COS cell lysates by Western blot, the truncated protein was not detected. Possible explanations for the lack of detection of the truncated protein are ...
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Follicle development as an orchestrated signaling network in a 3D organoid
... atic cell-secreted factors play important roles in early follicle development and may also impact how gonado- tropins affect the follicle during later stages of folliculo- ...and granulosa cells, and ...
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Granulosa cell-derived induced pluripotent stem cells exhibit pro-trophoblastic differentiation potential
... our granulosa parental cells were obtained from patients undergoing infertility treatment, there is a possibility that the granulosa cells carried gen- etic or epigenetic defects in the NLRP2 gene, thereby ...
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