• No results found

Overall Response Rate

A Single Institutional Phase II Randomized Trial of Whole Brain Radiation Therapy with or without Irinotecan for the Treatment of Brain Metastases from Solid Tumours

A Single Institutional Phase II Randomized Trial of Whole Brain Radiation Therapy with or without Irinotecan for the Treatment of Brain Metastases from Solid Tumours

... 46%). In a recent study examined the use of WBRT plus radiosensitizer versus WBRT conducted by Rojas-Pu- entes et al. [18] that evaluated the efficacy and safety of radiosensitization using chloroquine (CLQ) concomi- ...

12

Puquitinib mesylate, an inhibitor of phosphatidylinositol 3-kinase p110δ, for treating relapsed or refractory non- Hodgkin’s lymphoma

Puquitinib mesylate, an inhibitor of phosphatidylinositol 3-kinase p110δ, for treating relapsed or refractory non- Hodgkin’s lymphoma

... Results: Patients had received a median (range) of 1 (1 to 3) previous cancer treatments. At the latest follow-up, two patients were still benefitting from the study. The most common drug-related AEs were elevations in ...

8

Evaluation of noncytotoxic DNMT1 depleting therapy in patients with myelodysplastic syndromes

Evaluation of noncytotoxic DNMT1 depleting therapy in patients with myelodysplastic syndromes

... The overall response rate of 44% in this trial that had 36% subjects who relapsed or progressed through first-line 5-azacytidine and/or lenalidomide treatment compares favorably to the ...

14

Apatinib enhances chemosensitivity of gastric cancer to paclitaxel and 5-fluorouracil

<p>Apatinib enhances chemosensitivity of gastric cancer to paclitaxel and 5-fluorouracil</p>

... high overall response rate of 44 – ...The response rate of PTX monotherapy is optimal, reported as 20 – ...cant response and underwent potentially curative ...the response ...

11

Therapeutic potential of new B cell-targeted agents in the treatment of elderly and unfit patients with chronic lymphocytic leukemia

Therapeutic potential of new B cell-targeted agents in the treatment of elderly and unfit patients with chronic lymphocytic leukemia

... the overall response rate was 50 % versus 67 %, respectively, in treatment-naive patients and 45 % versus 64 % in relapsed/refractory patients, with no unexpected toxicities ...

9

Phase II study of neo adjuvant chemotherapy for locally advanced gastric cancer

Phase II study of neo adjuvant chemotherapy for locally advanced gastric cancer

... an overall response rate of ...and response rate in 5-FU versus capecitabine group, as well as cisplatin versus oxaliplatin ...partial response (PR) rate Summary ...

7

The impact of response rate on Hospital Consumer Assessment of Healthcare Providers and System (HCAHPS) dimension scores

The impact of response rate on Hospital Consumer Assessment of Healthcare Providers and System (HCAHPS) dimension scores

... the response rates achieved for each individual hospital. Response rates for all hospitals available in public reporting were evaluated for HCAHPS surveys conducted with patients discharged in calendar ...

11

Preoperative concurrent chemotherapy with S-1 and radiotherapy for locally advanced squamous cell carcinoma of the oral cavity: Phase I trial

Preoperative concurrent chemotherapy with S-1 and radiotherapy for locally advanced squamous cell carcinoma of the oral cavity: Phase I trial

... an overall response rate of 100% when treating oral and maxillary carcinoma with concur- rent chemoradiotherapy, using a combination of intraar- terial pirarubicin, intravenous continuous ...

6

Original Article Autologous platelet-rich gel for lower-extremity ischemic ulcers in patients with type 2 diabetes

Original Article Autologous platelet-rich gel for lower-extremity ischemic ulcers in patients with type 2 diabetes

... healing rate, overall response rate, the positive rate of bacterial culture of wound secretions and the degree of wound pain were compared between the two groups at one month after ...

6

Novel and emerging therapies for B cell lymphoma

Novel and emerging therapies for B cell lymphoma

... 52% overall response rate ...complete response (CR) remained in CR at the end of 6-month assessment ...good response and no serious adverse events (SAE) leading to treatment discontinu- ...

13

The efficacy and safety of anti-PD-1/PD-L1 antibodies for treatment of advanced or refractory cancers: a meta-analysis

The efficacy and safety of anti-PD-1/PD-L1 antibodies for treatment of advanced or refractory cancers: a meta-analysis

... the overall response rate was ...improved response and prolonged survival of anti-PD-1/PD-L1 antibodies were also supported by other trials for patients with metastatic non-small cell lung ...

12

Spotlight on ixazomib: potential in the treatment of multiple myeloma

Spotlight on ixazomib: potential in the treatment of multiple myeloma

... an overall response rate of the drug using only a single agent in relapsed MM with no prior use of a PI or less than six cycles of therapy with a previous ...an overall response ...

10

Rituximab and new regimens for indolent lymphoma: a brief update from 2012 ASCO Annual Meeting

Rituximab and new regimens for indolent lymphoma: a brief update from 2012 ASCO Annual Meeting

... Complete response; CRu: Complete response unconfirmed; PD: Pharmacodynamics; PK: Pharmacokinetics; PR: Partial response; ORR: Overall response rate; OS: Overall survival; ...

5

The significance of combining VEGFA, FLT1, and KDR expressions in colon cancer patient prognosis and predicting response to bevacizumab

The significance of combining <em>VEGFA</em>, <em>FLT1</em>, and <em>KDR</em> expressions in colon cancer patient prognosis and predicting response to bevacizumab

... ligand and the two receptors may be required for the activa- tion of the pathway. In addition, as shown in Figure 3, the consideration of all three genes together can better stratify patients into smaller groups with a ...

9

Meta analysis of acupuncture for relieving non organic dyspeptic symptoms suggestive of diabetic gastroparesis

Meta analysis of acupuncture for relieving non organic dyspeptic symptoms suggestive of diabetic gastroparesis

... Methods: We searched PubMed, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL) and four Chinese databases including China National Knowledge Infrastructure (CNKI), VIP Database for Chinese Technical ...

12

Heart rate variability in hyperthyroidism on sub Saharan African patients: a case–control study

Heart rate variability in hyperthyroidism on sub Saharan African patients: a case–control study

... heart rate due to sinus tachycardia but studies on catecholamine’s levels in hyperthyroidism revealed normal rate of plasma norepinephrine in thyrotoxicosis and additional data suggested that increased ...

5

Simeprevir with peginterferon α 2a/ribavirin for chronic hepatitis C virus genotype 1 infection in treatment experienced patients: an open label, rollover study

Simeprevir with peginterferon α 2a/ribavirin for chronic hepatitis C virus genotype 1 infection in treatment experienced patients: an open label, rollover study

... Statistical analyses were performed using SAS® version 9.2(SAS Institute Inc., Cary, NC, USA). All analyses were performed on the intent-to-treat (ITT) population (all patients who received at least one dose of ...

13

Treatment Outcomes of Advanced Stage Endometrial Carcinoma (Stage III-IV) and Related Factors

Treatment Outcomes of Advanced Stage Endometrial Carcinoma (Stage III-IV) and Related Factors

... treatment response, and recurrence ...complete response after primary treatment, and 94 ...survival rate was 50%, and the median recurrence-free interval was ...

8

Survey and analysis of patient safety culture in a county hospital

Survey and analysis of patient safety culture in a county hospital

... The data in this study were obtained from the survey con- ducted in a county hospital in Beijing from July to December 2014. The survey encompassed all health care workers (physicians, nurses, and allied health ...

12

Impact of JAK2(V617F) mutation status on treatment response to anagrelide in essential thrombocythemia: an observational, hypothesis-generating study

Impact of <em>JAK2</em>(<em>V617F</em>) mutation status on treatment response to anagrelide in essential thrombocythemia: an observational, hypothesis-generating study

... treatment response to anagrelide in patients with ET who were intolerant/refractory to their current cytoreductive ...platelet response (600×10 9 /L) after anagrelide ...

8

Show all 10000 documents...

Related subjects