OXADIAZOLE DERIVATIVES
Synthesis of some new 1,3,4 oxadiazole derivatives and evaluation of their antibacterial effects
... means. Oxadiazole have played important role in medicinal chemistry, such as anti-inflammatory[1,2], anticonvulsant[3], antifungal[4-7], antibacterial[8-11] and many ...substituted oxadiazole ...
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SYNTHESIS AND CHARACTERIZATION OF 1,3,4- OXADIAZOLE DERIVATIVES: DERIVED FROM IBUPROFEN
... An outsized figure of the non-steroidal anti- inflammatory drug is untaken clinically to care for acute and frequent provocative disorders. non-steroidal anti- inflammatory drugs are the generally normally prescribed ...
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NOVEL SYNTHESIS OF OXADIAZOLE DERIVATIVES WITH PYRIMIDINE MOIETY
... 5. Singh P, Sharma PK, Sharma JK, Upadhyay A and Kumar N: Synthesis and evaluation of substituted diphenyl -1,3,4-oxadiazole derivatives for central nervous system depressant activity. Organic and Medicinal ...
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Comparision study between convenstional method and mircrowave irradiation method to synthesize oxadiazole derivatives
... anti-HIV. Oxadiazole derivatives found to possess certain specific pharmacological ...some oxadiazole derivatives by conventional and microwave irradiation ...
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ANTIMICROBIAL AND ANTIFUNGAL EVALUATION OF NEWLY SYNTHESIZED OXADIAZOLE DERIVATIVES BEARING 2, 4, 5 TRIPHNENYL IMIDAZOLE MOIETY
... azole derivatives 4a-d have been synthesized from (2, 4, 5-triphenyl-imidazole-1-yl)-acetic acid hydrazide under various reaction ...synthesized oxadiazole derivatives have been investigated for ...
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A FACILE 1,2,4-OXADIAZOLE DERIVATIVES SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION
... 1,2,3-oxadiazole derivatives 6a-k were performed by the nucleophilic substitution of chlorine atom in 3- (4-bromo-2-fluorophenyl)-5-(chloromethyl)- 1,2,4-oxadiazole(4) by various substituted phenol ...
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Synthesis and characterization of novel benzothiophene substituted oxadiazole derivatives and their antimicrobial activity
... targeted oxadiazole derivatives 1-[5-(3-amino-1-benzothiophen-2-yl)-2-(3- nitrophenyl)-1,3,4-oxadiazol-3(2H)-yl]ethanone 5a was obtained in excellent ...
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A COMPREHENSIVE REVIEW ON ANTIMICROBIAL ACTIVITY OF 1,3,4-OXADIAZOLE DERIVATIVES
... is oxadiazole which has been found to exhibit various pharmacological ...activities. Oxadiazole is a five membered heterocyclic ring which is a versatile lead compound for designing potent bioactive ...
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MICROWAVE IRRADIATION SYNTHESIS AND ANTIOXIDANT ACTIVITY OF ISATIN-OXADIAZOLE DERIVATIVES
... isatin- oxadiazole derivatives have generated some useful ...3,(2,(5-mercapto-1,3,4- oxadiazole-2-yl)hydrazono)-5-bromo indolin 2-one showed most significant activity with Ic 50 values of ...
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SYNTHESIS, CHARACTERISATION AND BIOLOGICAL EVALUATION OF NOVEL OXADIAZOLE DERIVATIVES
... on which pharmacophores are arranged to provide potent and selective drugs. The synthesis of 1, 3, 4- oxadiazoles is of considerable interest due to their various biological activities such as anti-bacterial 1 , ...
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3D QSAR ANALYSIS ON OXADIAZOLE DERIVATIVES AS ANTICANCER AGENTS
... Three dimensional quantitative structure activity relationship (3D QSAR) study by means of partial least square regression (PLSR) method was performed on a series of 3-(Aryl)-N-(Aryl)-1, 2, 4-Oxadiazol-5-amines as ...
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“REVIEW EXPLORING ANTIINFLAMMATORY POTENTIAL OF 1,3,4-OXADIAZOLE DERIVATIVES AS PROMISING LEAD” by Suman Bala, Vipin Saini, Sunil Kamboj, D. N. Prasad, India. Digital copy link
... R. R. Kamble et al synthesized novel 1,3,4-oxadiazole derivatives, and tested them for their antiinflammatory activity. Bromination of P-acetylphenylsydnone, in presence of acetic acid, gave ...
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BIOLOGICAL SCREENING (IN VITRO) OF SOME 2, 5 DISUBSTITUTED OXADIAZOLE DERIVATIVES
... the derivatives of oxadiazoles have been playing an important role in the medicinal ...1,3,4-oxadiazole derivatives have been found to exhibit diverse biological activities such as antimicrobial, ...
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biological Aspects of 1,3,4 oxadiazole derivatives
... A new series of Mannich base of 1, 3, 4-oxadiazole derivatives possessing 1, 4-benzodioxan were synthesized by Ma et al. [38] All these novel compounds were screened for their in vitro anti-oxidant activity ...
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Synthesis and in vitro screening of some 1,3,4-oxadiazole derivatives as lipoxygenase inhibitors
... 2,5-disubstituted-1,3,4-oxadiazole derivatives of various Non Steroidal Anti- inflammatory Drugs were evaluated for in vitro activity in model of 5-lipoxygenase ...the oxadiazole derivatives ...
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Synthesis, characterization and optoelectronic investigations of thiophene substituted 1,3,4 oxadiazole derivatives as fluorescent materials
... 1,3,4- oxadiazole derivatives as donor-acceptor (D/A) systems which can be tuned either by altering the strength of D/A units or by extending π ...1,3,4- oxadiazole ring with electron rich aryl ...
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Synthesis of 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives
... 14. Mayekar A. N., Yathirajan H. S., Narayana B., Sarojini B. K., Kumari N.C., Synthesis and Antimicrobial Studies on New Substituted 1,3,4-Oxadiazole Derivatives Bearing 6- Bromonaphthalene Moiety. ...
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Synthesis, characterization, antibacterial and analgesic evaluation of some 1,3,4 oxadiazole derivatives
... Research on 1,3,4-oxadiazole and their synthetic analogs have revealed a variety of pharmacological activities including anti-microbial, antitubercular, anticancer, anti-HIV, antioxidant, analgesic, ...
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VARIOUS BIOLOGICAL ACTIVITIES OF COUMARIN AND OXADIAZOLE DERIVATIVES
... moiety. Substituted 1,3,4-oxadiazole derivatives have shown a broad spectrum of biological properties in pharmaceutical field. Among heterocyclic compounds, 1,3,4-oxadiazole has become an important ...
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“D Glucose” phase transfer catalyzed synthesis of benzimidazolyl oxadiazole derivatives
... In an yet another approach, the reaction of 2-(chloromethyl)-N-methylbenzimidazole (6) with 2- mercapto-5-phenyl-1,3,4-oxadiazoles (2a, i.e., 2, R=H) in DMF using D-glucose as PTC and potassium carbonate as base at room ...
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