Oxide Synthase Gene
Serum Nitric Oxide Level and Endothelial Nitric Oxide Synthase Gene INTRON4 VNTR Polymorphism in Essential Hypertension.
... Nitric oxide, the one considered to be the main factor involved in endothelial dysfunction, is found to be the main mediator involved in shear ...the gene level, reduced transcriptional activity of eNOS ...
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Original Article Effects of rs1799983 and rs1800779 polymorphisms in the endothelial nitric oxide synthase gene on migraine susceptibility with and without aura: a meta-analysis
... even gene- gene and gene-environmental exposure inter- ...considering gene-gene and gene-environment interactions are needed to provide a more comprehensive understanding of the ...
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C-786T (Promoter) Allelic Variants of Nitric Oxide Synthase Gene and Its Association with Nitric Oxide in Preeclampsia
... The three most common variants examined for clinical relevance, based on their potential functional effects are (i) a G894T substitution in exon 7 resulting in a Glu to Asp substitution at codon 298 (rs1799983), (ii) an ...
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Production of a plasmid to facilitate gene interruption of the nitric oxide synthase gene from Bacillus subtilis
... KAN gene has inserted into the genome at some locus, and it is statistically unlikely that this occurred at a random region of the genome (although this possibility is not being ...
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Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre eclampsia: a case control study and a meta analysis
... Pre-eclampsia is thought to have an important genetic component [6,7]. Several studies have reported associa- tions between pre-eclampsia and polymorphisms of vari- ous genes [8-10]. However, the lack of reproducibility ...
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Characterization and Functional Analysis of the Human Inducible Nitric Oxide Synthase Gene Promoter
... Comparison of the lucif- erase activity using the human 1800-bp promoter and nitric oxide production of A549 cells activated with various cytokines alone or in combination. Equal numbers[r] ...
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Association of the 894G>T polymorphism in the endothelial nitric oxide synthase gene with risk of acute myocardial infarction
... eNOS gene alters the functional profile of the protein, trying to provide a pathophysiolog- ical background which could support the clinical hypoth- esis of association between this polymorphism and several ...
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The Evaluation of Serum Nitrite, Nitrate and Malonyldialdehyde Levels in Smokers
... nitric oxide synthase gene expression and enzyme ...nitric oxide synthase expression in the rat ...Nitric oxide and the ...
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The effects of oxidized low density lipoproteins on inducible mouse macrophage gene expression are gene and stimulus dependent
... suppress gene expression varied markedly with the inducing stimulus ...nitric oxide synthase gene were suppressed by oxidized LDL while the antagonistic effect of IFN gamma on LPS-induced ...
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Polymorphisms of the endothelial nitric oxide synthase (NOS3) gene in preeclampsia: a candidate gene association study
... nitric oxide synthase gene (NOS3), located at the 7q35-q36 region, has emerged as a logical candidate gene in the development of ...NOS3 gene have been investigated for association with ...
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Avian immunology, immunogenetics, and host immune response to Salmonella enterica serovar Enteritidis infection in chickens
... nitric oxide synthase) gene would affect IFN-γ induced macrophage production of nitric oxide (NO) and mRNA expression of genes involved in this biological pathway in the ...
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GENE POLYMORPHISM OF ENDOTHELIAL NITRIC OXIDE SYNTHASE IN PATIENTS WITH STABLE ANGINA PECTORIS AND ITS SIGNIFICANCE IN THE MANIFESTATION OF GENOPROTECTIVE PROPERTIES OF MELDONIUMOlesya V. Romaschenko*, Eduard A. Snegin, Lyudmila R. Zakirova, Elena B. Artyushkova, Galina A. Batischeva, Natalya A. Bystrova, Vladimir Y. ProvotorovDOWNLOAD/VIEW
... nitric oxide synthase gene, eNOS C786T, and genoprotective properties under the normal genotype of eNOS C786T, is a new ...nitric oxide synthase in patients with the pathological eNOS ...
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Regulation of extracellular arginine levels in the hippocampus in vivo
... (1994) Constitutive and inducible nitric oxide synthase gene expression, regulation and activity in human lung epithelial cells.. (1993) Feedback inhibition o f nitric oxide synthase[r] ...
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Correlation of Glu298Asp eNOS Polymorphism with Serum NO Levels in Egyptian Patients with Coronary Artery Disease
... In contrast to the previous results, Nassar et al. [23] did not find any association between the G894T polymorphism and CAD incidence in Canadian subjects with a history of MI or angina pectoris plus angiographically ...
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Nitrite Derived from Endogenous Bacterial Nitric Oxide Synthase Activity Promotes Aerobic Respiration
... to water (23). The cytochrome bo oxidase also translocates protons across the cytoplasmic membrane, thus contributing to a membrane potential (23). Previously, it was shown that nitrites, like nitric oxide, can ...
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The pulmonary circulation of homozygous or heterozygous eNOS null mice is hyperresponsive to mild hypoxia
... which to test the role of EDNO in modulating pul- monary vascular responses to hypoxia. However, whether eNOS is ever deficient in the pulmonary circulation of humans is controversial. Giaid et al. (35) found that eNOS ...
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Nitric oxide production in the mammary gland : a thesis submitted in partial fulfilment for the degree of Doctor of Philosophy at Massey University, New Zealand
... No data are available in the literature on the content of eNOS mRNA in the m amm ary gland although there have been studies in which eNOS immunoreactive protein was measured in the secretory epithelium during lactation ...
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Effects of cigarette smoke on degranulation and NO production by mast cells and epithelial cells
... Nitric oxide is a ubiquitous intracellular and intercellular signaling molecule, which plays a role in the functions of various inflammatory cells including mast cells, lym- phocytes, neutrophils and macrophages ...
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Original Article Gene polymorphisms of nitric oxide synthase (G-954C, G894T) and sorbitol dehydrogenase (C-1214G, G-888C) in Chinese patients with diabetic retinopathy combined with cystoid macular edema
... phism sites of SDH gene. There were few reports about SDH C-1214G in DR or T2DM, the same was to SDH G-888C. In our study, G-888C was not related to DR in Chinese patients, which was similar to the result found in ...
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Investigating the effects of targeting nitric oxide pathways in a kainic acid mouse model of epileptogenesis
... and gene model 1604B was significantly up-regulated in comparison to control (Table ...1995). Gene model 1604b closely interacts with gene model 1381, REV1 homolog and secretory carrier membrane ...
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