Oxytocin Receptor
Vasopressin stimulated phosphoinositide hydrolysis in cultured rat inner medullary collecting duct cells is mediated by the oxytocin receptor
... desGlyNH2d(CH2)5[Tyr(Me)-Thr4]OVT (10(-7) M) does not inhibit AVP-stimulated cAMP production but eliminates IP3 production in response to AVP or the V2 receptor agonist VDAVP. These studies demonstrate that AVP or ...
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Unexpected evolutionarily conserved rapid effects of viral infection on oxytocin receptor and TGF-β/pSmad3
... on oxytocin receptor (OXTR) expression through the ERK/MAPK pathway in mouse and human skeletal muscle cells, on myogenic activity, and in vivo on mouse muscle ...
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Original Article Expression of oxytocin receptor in the rat superior cervical ganglion after myocardial infarction
... The oxytocin (OT) -oxytocin receptor (OTR) system has been known for its pivotal role in many aspects of mammalian reproduc- tion as well as several other physiological pro- cesses such as bond ...
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Up regulation of oxytocin receptor gene and protein in the sheep anterior pituitary by a dopamine derivative (salsolinol)
... tion of these hypothalamic neurons leads to OT release into the circulation where it is transported to different peripheral tissues (Gimpl and Fahren- holz 2001). OT released from centrally projecting oxytocinergic ...
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Association of oxytocin receptor (OXTR) gene variants with multiple phenotype domains of autism spectrum disorder
... The functional significance of these findings is yet to be determined. Although none of the genome-wide association studies highlighted the OXTR gene at chromosome 3p25, two described suggestive evidence for association ...
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Evidence that genetic variation in the oxytocin receptor (OXTR) gene influences social cognition in ADHD
... the oxytocin receptor gene (OXTR) exhibit social impairment (Lee et ...studies, oxytocin plasma levels have been found to be decreased in some prepubertal individuals with autism compared to non ...
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The oxytocin receptor gene predicts brain activity during an emotion recognition task in autism
... Genotyping was conducted for seven oxytocin receptor ( OXTR ) single nucleotide olymorphisms (SNPs)— rs7632287, rs2268491, rs237887, rs2254298, rs53576, rs2268493, and rs2228485. These SNPs were selected ...
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Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex
... targeting oxytocin receptor expression and targeting several gene ontology pathways that are relevant to autism, including synapse function and signal ...
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Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies.
... Prenatal stress exposure, oxytocin receptor gene (OXTR) methylation, and child autistic traits: the moderating role of OXTR rs53576 genotype.. Pagnoni, G., 2014.[r] ...
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Sexually dimorphic effects of oxytocin receptor gene (OXTR) variants on Harm Avoidance
... the oxytocin receptor gene in Harm Avoidance and incentivize resequencing the OXTR gene in condi- tions marked by an increased sensitivity to perceived ...to oxytocin-mediated adaptive responses in ...
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The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review
... ‘oxytocin receptor gene’ and ‘epigenetics’ or ‘DNA methylation’ and limited to studies involving humans and those written in ...or oxytocin ‘receptor gene’ and one of ‘epigenetics’ or ‘DNA ...
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The Oxytocin Receptor Gene (OXTR) and Gazing Behavior during Social Interaction: An Observational Study in Young Adults
... Social relationships are essential in human development. Having close social bonds is associated with several positive outcomes, whereas social exclusion is related to decreases in wellbeing and psychological health ...
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The association of childhood maltreatment with depression and anxiety is not moderated by the oxytocin receptor gene
... Background The oxytocin receptor (OXTR) gene may be involved in resilience or vulnerability towards stress, and hence in the development of stress-related disorders. There are indications that OXTR single ...
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Genomic and epigenetic evidence for oxytocin receptor deficiency in autism
... gain (n = 3) that contained 21 genes (Additional file 3). According to Fable http://fable.chop.edu/ only one gene within these novel regions, ring finger protein 19A (RNF19A, also known as p38) in a 0.6 Mb deletion on ...
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The oxytocin receptor antagonist, Atosiban, activates pro inflammatory pathways in human amnion via Gαi signalling
... Oxytocin (OT) plays an important role in the onset of human labour by stimulating uterine contractions and promoting prostaglandin/inflammatory cytokine synthesis in amnion via oxytocin receptor (OTR) ...
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The ovine endometrial oxytocin receptor
... each oxytocin pulse peaks it is thought to down regulate its own receptor and induce transient uterine refractoriness to ...novo oxytocin receptor (OTR) synthesis and this is thought to ...
295
Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFα and IL-13
... whether oxytocin receptor expression was modulated by pro-inflammatory cytokines, TNFa, IL- 13 and IL-13R130Q, a naturally occurring isoform of IL-13 and associated with high serum IgE levels ...for ...
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The effect of oxytocin receptor blockade on parturition in guinea pigs
... An oxytocin antagonist (des-Gly9-[D-Trp2,Thr4,Orn8]dC6- oxytocin, 20 micrograms/kg per h, n = 11) or saline solution (n = 12) was infused starting on day 66 of gestation (term is 69 ...d). Oxytocin ...
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<p>In vitro comparison of liposomal drug delivery systems targeting the oxytocin receptor: a potential novel treatment for obstetric complications</p>
... Notes: conventional liposomes and rabbit Igg immunoliposomes were used as controls. competitive inhibition of binding of OTr-targeted liposomes was also evaluated following preincubation with excess anti-OTr monoclonal ...
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Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome
... for oxytocin (OXT) and oxytocin receptor (OXTR) genes in social-emotional behaviors, and several studies indicate that the oxytocin/oxytocin receptor system is altered in ...
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