P. berghei ANKA
Experimental malaria associated acute respiratory distress syndrome is dependent on the parasite host combination and coincides with normocyte invasion
... P. berghei is known to have preference for invading reticulocytes versus normocytes ...of P. berghei ANKA was completely ...with P. berghei NK65-NY, and could even be ...
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Elevated IL 17 levels in semi immune anaemic mice infected with Plasmodium berghei ANKA
... This line of P. berghei ANKA was generously donated by Dr. Tetsuo Yanagi, of National Bio-Resource Center (NBRC), NEKKEN, Nagasaki University, Nagasaki, Japan. For every 2 days, levels of ...
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IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection
... has been recently shown that MIG 2/2 and IP-10 2/2 mice are partially resistant to P. berghei ANKA infection [20]. However, whether the increased survival rates to malaria infection in the absence of ...
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ICAM 1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria model
... (P. berghei ANKA) and infections of mice defi- cient in ICAM-1 expression (icam1−/−) show improved survival [20, 21] and reduced sequestration in the alveo- lar capillaries of the lung ...in ...
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Antimalarial efficacy of Pongamia pinnata (L) Pierre against Plasmodium falciparum (3D7 strain) and Plasmodium berghei (ANKA)
... Methods: The plant Pongamia pinnata was collected from the herbal garden of Acharya Nagarjuna University of Guntur district, Andhra Pradesh, India. Sequentially crude extracts of methanol (polar), chloroform (non-polar), ...
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Bone marrow chimeric mice reveal a dual role for CD36 in Plasmodium berghei ANKA infection
... Although clear differences between malaria infections in humans and mice exist, certain aspects of the infection are comparable [26]. CD36 expression and CD36-mediated adhesion of iRBCs to the microvasculature, for ...
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Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria
... Figure 1. In the absence of LT the early death of P. berghei ANKA-parasitized C57BL/6 mice is pre- vented. (a) LT mRNA is up-regulated in brains of C57BL/6 mice with CM, as indicated by real-time ...
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Upper gastrointestinal pathophysiology due to mouse malaria Plasmodium berghei ANKA infection
... Mice infected with P. berghei ANKA (PbA) [9] are widely used as a mouse model of malaria infection. PbA-infected C57BL/6 (PbA-C57BL/6) mice are the best-known cerebral malaria models [10, 11], and ...
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Anti plasmodial activities of Combretum molle (Combretaceae) [Zwoo] seed extract in Swiss albino mice
... Plasmodium berghei ANKA (PbA) infected control (neg- ative control) and (ii) PbA infected chloroquine (positive control) treated ...of P. berghei ANKA (PbA) parasite was used to infect ...
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Germinal center architecture disturbance during Plasmodium berghei ANKA infection in CBA mice
... Some works have addressed the lymphoid reactions in malaria infections, most data coming from the P. chabaudi model and focused in spleen changes. Sanchez-Torres and coworkers [18] have described the enlargement ...
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Lambda carrageenan treatment exacerbates the severity of cerebral malaria caused by Plasmodium berghei ANKA in BALB/c mice
... It is also possible that although the clinical signs asso- ciated with ECM in the untreated group were not ob- served, these mice may also have developed ECM, as reported by Neill and Hunt [23]. It will be interesting to ...
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From METS to malaria: RRx 001, a multi faceted anticancer agent with activity in cerebral malaria
... with P. berghei ANKA and, on day 6 of infec- tion, they were lightly anesthetized with isoflurane (4 % for induction, 1–2 % for maintenance) and held on a stereotaxic frame for measurements of pH and ...
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Further evidence for an anti inflammatory role of artesunate in experimental cerebral malaria
... A recent study conducted by Linares et al. [11] demon- strated an increase in IFN-γ and TNF mRNA expression in several brain areas of P. berghei-infected mice, including cortex, hippocampus, ...
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Long term effect of uncomplicated Plasmodium berghei ANKA malaria on memory and anxiety like behaviour in C57BL/6 mice
... The late impact of the uncomplicated malaria on cogni- tive performance is still poorly understood. The present study aimed at searching for a long-lasting influence of un- complicated experimental murine malaria on ...
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Malaria and obesity: obese mice are resistant to cerebral malaria
... by P. berghei ANKA is known to be under genetic regulation, but the mechanisms leading to protection versus death from cerebral malaria are not yet fully understood in normal non-obese mice ...by ...
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Tim 3 signaling blockade with α lactose induces compensatory TIGIT expression in Plasmodium berghei ANKA infected mice
... membrane protein 1; LAG-3: lymphocyte activation gene-3; CTLA-4: cytotoxic T-lymphocyte-associated protein-4; PD-1: programmed death-1; TNF-α: tumor necrosis factor alpha; PbA: P. berghei ANKA; i.p.: ...
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REVIEW ARTICLE Changes in brain metabolites in experimental cerebral malaria infection with plasmodium berghei ANKA: A literature review
... Routine use of MRS can provide novel evidences towards disease pathology and treatment. MR techniques represent a good and probably the ultimate future solution towards entangling the knots behind P. falciparum ...
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Immunization of mice with soluble lysate of interferon gamma expressing Plasmodium berghei ANKA induces high IFN-γ production
... Methods: Soluble lysate of transgenic PbA (TPbA) was prepared and concentration of IFN- γ in lysate determined by ELISA. Four groups of 20 BALB/c mice each (two treatment groups and two control groups) were setup. ...
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Plasmodium berghei ANKA infection increases Foxp3, IL 10 and IL 2 in CXCL 10 deficient C57BL/6 mice
... Regulatory T cells are key cerebroprotective immuno- modulators during acute strokes in murine model. Absence of CD4+CD25+Foxp3+ enhanced activation of resident and invading inflammatory cells (microglia and T-cells) to ...
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Effect of crude leaf extract of Osyris quadripartita on Plasmodium berghei in Swiss albino mice
... Methods: Aqueous, chloroform and methanol crude leaf extracts of the plant have been prepared and tested for acute toxicity and anti-malarial efficacy in Plasmodium berghei (ANKA strain)-infected Swiss ...
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