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p/sup +/-i-n/sup +/ accelerating junction

An integrated safety analysis of combined acetaminophen and ibuprofen (Maxigesic®/ Combogesic®) in adults

<p>An integrated safety analysis of combined acetaminophen and ibuprofen (Maxigesic<sup>&reg;</sup>/ Combogesic<sup>&reg;</sup>) in adults</p>

... Phase I clinical trials, 14 AEs were reported within 72 hours of drug administration amongst 10 patients (Table ...Phase I clinical trials had no reported AEs. During the other five Phase I studies, ...

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A Synthetic Peptide 2Abz23S29 Reduces Bacterial Titer and Induces Pro-Inflammatory Cytokines in a Murine Model of Urinary Tract Infection

<p>A Synthetic Peptide 2Abz<sup>23</sup>S<sup>29</sup> Reduces Bacterial Titer and Induces Pro-Inflammatory Cytokines in a Murine Model of Urinary Tract Infection</p>

... In sup- port of this, Miles et al reported that systemic administra- tion of HNP-1 protects peritonitis mice and plays a translation-based anti-in fl ammatory role in ...

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ClariVein&reg;, mechanochemical endovenous ablation: patient selection and perspective

<p>ClariVein<sup>&reg;</sup>, mechanochemical endovenous ablation: patient selection and perspective</p>

... Lower pain scores with MOCA were con fi rmed in a randomised controlled trial (RCT) of MOCA (Clarivein) versus RFA (Vene fi t). One hundred and seventy patients with primary truncal venous incompetence were recruited and ...

8

Evaluating Nephrocheck&reg; as a Predictive Tool for Acute Kidney Injury

<p>Evaluating Nephrocheck<sup>&reg;</sup> as a Predictive Tool for Acute Kidney Injury</p>

... deceased donor. 23 were diagnosed with DGF. There were no differences in age, gender, causes of end-stage renal disease, ischemic time, or degree of HLA mismatch between the patients with early graft function and DGF. In ...

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IN.PACTTM AdmiralTM drug-coated balloons in peripheral artery disease: current perspectives

<p>IN.PACT<sup>TM</sup> Admiral<sup>TM</sup> drug-coated balloons in peripheral artery disease: current perspectives</p>

... DEEP trial, a total of 358 patients mostly with CLI were randomized to IN.PACT Amphirion DCB treatment group or BA treatment group. Coprimary efficacy outcomes were TLR and angiographic LLL at 12 months, and the primary ...

12

Outcome Of MicroPulse&reg; Transscleral Photocoagulation In Different Types Of Glaucoma

<p>Outcome Of MicroPulse<sup>&reg;</sup> Transscleral Photocoagulation In Different Types Of Glaucoma</p>

... Results: A total of 71 eyes of 68 patients (39 males, 29 females) aged 60.0 years (13 – 89 years) were treated with µP-TSCPC. The most common diagnosis was neovascular glaucoma. The safety index of corrected distance ...

8

Radiation therapy-induced reactive oxygen species specifically eliminates CD19+&nbsp;IgA+&nbsp;B cells&nbsp;in nasopharyngeal carcinoma

<p>Radiation therapy-induced reactive oxygen species specifically eliminates CD19<sup>+</sup>&nbsp;IgA<sup>+</sup>&nbsp;B cells&nbsp;in nasopharyngeal carcinoma</p>

... cells sup- press in fl ammation by secreting anti-microbial antibodies, whereas CD19 + CD138 − IgA + cells negatively regulate anti- tumor effectors by expressing PD-1 and producing TGF- β ...

11

Pretreatment detection of circulating and tissue CD133+&nbsp;CD44+ cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer

<p>Pretreatment detection of circulating and tissue CD133<sup>+&nbsp;</sup>CD44<sup>+</sup> cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer</p>

... Descriptive data in the form of mean, median, range, SD, and percentages were used. Mann–Whitney U-test was used to find a relation between two groups of ordinal variables, chi-squared test between ≥ 2 groups of ...

12

Comparison of head-mounted perimeter (imo&reg;) and Humphrey Field Analyzer

<p>Comparison of head-mounted perimeter (imo<sup>&reg;</sup>) and Humphrey Field Analyzer</p>

... Patients and methods: imo examinations (either head-mounted [i-H] or fixed [i-F] type) were performed in patients with glaucoma or suspected glaucoma who had already experienced HFA five or more times. ...

13

TearCare&reg; system extension study: evaluation of the safety, effectiveness, and durability through 12 months of a second TearCare&reg; treatment on subjects with dry eye disease

<p>TearCare<sup>&reg;</sup> system extension study: evaluation of the safety, effectiveness, and durability through 12 months of a second TearCare<sup>&reg;</sup> treatment on subjects with dry eye disease</p>

... the P-values were the result of separate tests of whether the mean difference = 0 for each follow-up time ...the P-values were from simple mixed-effects linear models (with no covariates) that allow for ...

10

Remicade&reg;&nbsp;(infliximab):&nbsp;20 years of contributions to science and medicine

<p>Remicade<sup>&reg;</sup>&nbsp;(infliximab):&nbsp;20 years of contributions to science and medicine</p>

... ACCENT I and II trials for luminal and fi stulizing disease, ...ACCENT I or 5 mg/kg in ACCENT II) or placebo maintenance q8w for 1 ...ACCENT I, at crossover, the dose was administered upon symptom ...

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Partial sciatic nerve ligation leads to an upregulation of Ni2+-resistant T-type Ca2+ currents in capsaicin-responsive nociceptive dorsal root ganglion neurons

<p>Partial sciatic nerve ligation leads to an upregulation of Ni<sup>2+</sup>-resistant T-type Ca<sup>2+</sup> currents in capsaicin-responsive nociceptive dorsal root ganglion neurons</p>

... ricated from borosilicate glass capillaries (Science Products, Hofheim, Germany) using a P-97 Flaming/Brown Micro- pipette Puller (Sutter Instrument Company, Novato, CA, USA). One cell per culture dish was ...

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Combined Therapeutic Effects of 131I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer

<p>Combined Therapeutic Effects of <sup>131</sup>I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer</p>

... 131 I and PEG-PLA- 131 I PEG-PLA-5Fu and PEG-PLA were labeled with 131 I via the chemical iodide ...131 I was added into PEG-PLA-5Fu or PEG-PLA (10 mg/mL, 1 ...131 I was removed by ...

11

An Immunoscore System Based On CD3+ And CD8+ Infiltrating Lymphocytes Densities To Predict The Outcome Of Patients With Colorectal Adenocarcinoma

<p>An Immunoscore System Based On CD3<sup>+</sup> And CD8<sup>+</sup> Infiltrating Lymphocytes Densities To Predict The Outcome Of Patients With Colorectal Adenocarcinoma</p>

... Overall, 106 patients with colorectal cancer were included (Table 1). The sex ratio (Men/Women: 64/ 42) was equal to 1.5 and the mean age for Men was 62.07 years [33 to 84 years], whereas for Women it was 61.98 years [25 ...

11

Addition Of A Sleeve To The Etanercept Autoinjector (Enbrel&reg; MyClic&reg;) Improves Ease Of Use In Patients With Rheumatoid Arthritis

<p>Addition Of A Sleeve To The Etanercept Autoinjector (Enbrel<sup>&reg;</sup> MyClic<sup>&reg;</sup>) Improves Ease Of Use In Patients With Rheumatoid Arthritis</p>

... Patients and methods: Twenty-four adult patients (16 female) with RA and varying degrees of manual dexterity impairment took part in this user study. Written informed consent was supplied by each patient prior to ...

8

Efficacy and safety of tiotropium + olodaterol maintenance treatment in patients with COPD in the TONADO&reg; and OTEMTO&reg; studies: a subgroup analysis by age

<p>Efficacy and safety of tiotropium + olodaterol maintenance treatment in patients with COPD in the TONADO<sup>&reg;</sup> and OTEMTO<sup>&reg;</sup> studies: a subgroup analysis by age</p>

... years, n=749; 65 years to ,75 years, n=674; 75 years to ,85 years, n=186; $85 years, n=12) in OTEMTO and 5,162 patients (40 years to ,65 years, n=2,654; 65 years to ,75 years, ...

10

Optimization of the Oertli CataRhex 3&reg; phacoemulsification machine

<p>Optimization of the Oertli CataRhex 3<sup>&reg;</sup> phacoemulsification machine</p>

... microchatter or bounce around the tip for several seconds before a proper vacuum seal is established to allow prompt emulsification. New mean values and SDs were thus recalculated to reduce noise in the data. For vacuum ...

7

Asthma patients prefer Respimat&reg; Soft Mist&trade; Inhaler to Turbuhaler&reg;

Asthma patients prefer Respimat<sup>&reg;</sup> Soft Mist<sup>&trade;</sup> Inhaler to Turbuhaler<sup>&reg;</sup>

... a questionnaire on patient device preference and satisfaction (PASAPQ) as part of a psycho- metric validation. As the study used a double-dummy design to maintain blinding, patients used and assessed both devices, rating ...

8

Tobramycin administered by the TOBI&reg; Podhaler&reg; for persons with cystic fibrosis: a review

Tobramycin administered by the TOBI<sup>&reg;</sup> Podhaler<sup>&reg;</sup> for persons with cystic fibrosis: a review

... nebulizer powered by an air compressor over 15–20 minutes. Comparative pharmacokinetics, safety, and efficacy studies of TIS and TIP in CF subjects with P. aeruginosa $ 6 years old demonstrate that: tobramycin ...

10

Comparison of outcomes of conventional WaveLight&reg; Allegretto Wave&reg; and Technolas&reg; excimer lasers in myopic laser in situ keratomileusis

Comparison of outcomes of conventional WaveLight<sup>&reg;</sup> Allegretto Wave<sup>&reg;</sup> and Technolas<sup>&reg;</sup> excimer lasers in myopic laser in situ keratomileusis

... In this study, within the subgroups treated for − 2.5 to − 4.0 D, the percentages of eyes achieving ± 0.50 and within ± 0.25 D from plano (meaning “flat” – ie, no vision correction needed) for Allegretto Wave were 86.8% ...

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