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p/sup +//spl pi/p/sup +/ junction

IN.PACTTM AdmiralTM drug-coated balloons in peripheral artery disease: current perspectives

<p>IN.PACT<sup>TM</sup> Admiral<sup>TM</sup> drug-coated balloons in peripheral artery disease: current perspectives</p>

... DEEP trial, a total of 358 patients mostly with CLI were randomized to IN.PACT Amphirion DCB treatment group or BA treatment group. Coprimary efficacy outcomes were TLR and angiographic LLL at 12 months, and the primary ...

12

Comparing radiopaque markers and 13C-labelled breath test in diabetic gastroparesis diagnostics

<p>Comparing radiopaque markers and <sup>13</sup>C-labelled breath test in diabetic gastroparesis diagnostics</p>

... Patients and methods: Forty- fi ve patients (30 women, 15 men) with diabetes mellitus types 1 or 2 (40, 5) and symptoms of gastroparesis were examined with ROM and GEBT. All were interviewed, fi lled out symptom ...

9

A Synthetic Peptide 2Abz23S29 Reduces Bacterial Titer and Induces Pro-Inflammatory Cytokines in a Murine Model of Urinary Tract Infection

<p>A Synthetic Peptide 2Abz<sup>23</sup>S<sup>29</sup> Reduces Bacterial Titer and Induces Pro-Inflammatory Cytokines in a Murine Model of Urinary Tract Infection</p>

... Since cytokines can play a pivotal role in the devel- opment and spread of the immune response to bacterial infections, in this study, we also examined the levels of pro-in fl ammatory cytokines including, MIP/2, IL-6, ...

11

Pretreatment detection of circulating and tissue CD133+&nbsp;CD44+ cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer

<p>Pretreatment detection of circulating and tissue CD133<sup>+&nbsp;</sup>CD44<sup>+</sup> cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer</p>

... Descriptive data in the form of mean, median, range, SD, and percentages were used. Mann–Whitney U-test was used to find a relation between two groups of ordinal variables, chi-squared test between ≥ 2 groups of ...

12

Assessment of Acceptability and Ease of Use of Haemoglobin Spray (Granulox&reg;) in the Management of Chronic Wounds

<p>Assessment of Acceptability and Ease of Use of Haemoglobin Spray (Granulox<sup>&reg;</sup>) in the Management of Chronic Wounds</p>

... One retrospective, controlled, prospective cohort study eval- uated the use of the haemoglobin spray-on diabetic foot ulcers (DFU). 7,37 These patients have a greater than two-fold increase in mortality compared with ...

10

PD-L1 in Lung Adenocarcinoma: Insights into the Role of 18F-FDG PET/CT

<p>PD-L1 in Lung Adenocarcinoma: Insights into the Role of <sup>18</sup>F-FDG PET/CT</p>

... The association between two continuous variables was analyzed by Mann – Whitney U-test or t-test. The associa- tion between two categorical variables was evaluated by chi-square test. The Spearman correlation analysis ...

11

Radiation therapy-induced reactive oxygen species specifically eliminates CD19+&nbsp;IgA+&nbsp;B cells&nbsp;in nasopharyngeal carcinoma

<p>Radiation therapy-induced reactive oxygen species specifically eliminates CD19<sup>+</sup>&nbsp;IgA<sup>+</sup>&nbsp;B cells&nbsp;in nasopharyngeal carcinoma</p>

... cells sup- press in fl ammation by secreting anti-microbial antibodies, whereas CD19 + CD138 − IgA + cells negatively regulate anti- tumor effectors by expressing PD-1 and producing TGF- β ...

11

TearCare&reg; system extension study: evaluation of the safety, effectiveness, and durability through 12 months of a second TearCare&reg; treatment on subjects with dry eye disease

<p>TearCare<sup>&reg;</sup> system extension study: evaluation of the safety, effectiveness, and durability through 12 months of a second TearCare<sup>&reg;</sup> treatment on subjects with dry eye disease</p>

... the P-values were the result of separate tests of whether the mean difference = 0 for each follow-up time ...the P-values were from simple mixed-effects linear models (with no covariates) that allow for ...

10

P53 Mutant p53N236S Regulates Cancer-Associated Fibroblasts Properties Through Stat3 Pathway

<p>P53 Mutant p53<sup>N236S</sup> Regulates Cancer-Associated Fibroblasts Properties Through Stat3 Pathway</p>

... Our previous study showed that p53 S/S mice manifested to an early onset of sarcomas that metastasized to various organs, such as liver and lung. 15 We attempted to under- stand the phenotypes resulting from the p53S ...

9

RNA m6A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway

<p>RNA m<sup>6</sup>A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway</p>

... Figure 4 Effects of METTL3 depletion on SHH-GLI pathway and apoptosis. (A)The protein level of SHH-GLI pathway was analyzed by Western blotting after METTL3 depletion. (B, C) The mRNA level of c-Myc and cycling D1 was ...

10

Combined Therapeutic Effects of 131I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer

<p>Combined Therapeutic Effects of <sup>131</sup>I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer</p>

... tumor growth slightly compared with saline or blank Cet-PEG -PLA treatment (Figures 6A and B). Moreover, the combina- tion treatment of Cet-PEG-PLA-5Fu- 131 I markedly sup- pressed tumor growth, revealing the ...

11

XEN&reg; Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma

<p>XEN<sup>&reg;</sup> Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma</p>

... A prospective multicenter nonrandomized trial by Reitsamer et al 32 compared results of Xen 45 solo (n=120) and Xen 45 combo (n=98) with 2-year follow-up in uncon- trolled moderate POAG. Two-hundred and forty eyes of 218 ...

28

Comparison of head-mounted perimeter (imo&reg;) and Humphrey Field Analyzer

<p>Comparison of head-mounted perimeter (imo<sup>&reg;</sup>) and Humphrey Field Analyzer</p>

... Spearman’s rank-order correlation coefficient was calculated for correlations between HFA and i-H type, i-F type, and i-T. Bland–Altman plots were used to analyze the systematic errors of both; a straight line ...

13

ClariVein&reg;, mechanochemical endovenous ablation: patient selection and perspective

<p>ClariVein<sup>&reg;</sup>, mechanochemical endovenous ablation: patient selection and perspective</p>

... In the following year, van Eekrren 23 and his colleagues evaluated 92 patients (106 limbs) undergoing MOCA for GSV insuf fi ciency. Sixty-seven of the patients were females with a mean age of 52 years. Two concentration ...

8

Optimization of the Oertli CataRhex 3&reg; phacoemulsification machine

<p>Optimization of the Oertli CataRhex 3<sup>&reg;</sup> phacoemulsification machine</p>

... microchatter or bounce around the tip for several seconds before a proper vacuum seal is established to allow prompt emulsification. New mean values and SDs were thus recalculated to reduce noise in the data. For vacuum ...

7

An Immunoscore System Based On CD3+ And CD8+ Infiltrating Lymphocytes Densities To Predict The Outcome Of Patients With Colorectal Adenocarcinoma

<p>An Immunoscore System Based On CD3<sup>+</sup> And CD8<sup>+</sup> Infiltrating Lymphocytes Densities To Predict The Outcome Of Patients With Colorectal Adenocarcinoma</p>

... Results: The density of CD3 + and CD8 + was signi fi cantly associated with 5-year overall survival (P=0.001 and P=0.00098, respectively) and 5-year disease-free survival (P=0.0006 and ...

11

Evaluating Nephrocheck&reg; as a Predictive Tool for Acute Kidney Injury

<p>Evaluating Nephrocheck<sup>&reg;</sup> as a Predictive Tool for Acute Kidney Injury</p>

... deceased donor. 23 were diagnosed with DGF. There were no differences in age, gender, causes of end-stage renal disease, ischemic time, or degree of HLA mismatch between the patients with early graft function and DGF. In ...

12

Outcome Of MicroPulse&reg; Transscleral Photocoagulation In Different Types Of Glaucoma

<p>Outcome Of MicroPulse<sup>&reg;</sup> Transscleral Photocoagulation In Different Types Of Glaucoma</p>

... Results: A total of 71 eyes of 68 patients (39 males, 29 females) aged 60.0 years (13 – 89 years) were treated with µP-TSCPC. The most common diagnosis was neovascular glaucoma. The safety index of corrected distance ...

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