p53 codon 72
Review Article p53 codon 72 polymorphism is associated with human papillomavirus-related esophageal cancer risk: a meta-analysis
... of p53 tumor sup- pressor protein via a ubiquitin-mediated pro- cess ...of p53 Arg72Pro polymor- phism in the development of HPV-related can- cer was first proposed in 1998 ...of p53 codon ...
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Association of p53 codon 72 Arg>Pro polymorphism and risk of cancer in Iranian population: A systematic review and meta-analysis
... genome". P53 is one of the most frequently mutated genes in human malignan- cies and more than 50% of human cancers ...the P53 function. In particular, P53 Codon 72 (P53c72) single ...
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Evidence of Interaction between PTPN22 and p53 codon 72 Polymorphisms on Susceptibility to Immune Related Diseases
... Clinical data of the patients and controls are shown in Table 1. Table 2 shows the proportion of *T allele carriers in *Arg/*Arg genotype and in *Pro allele carriers of p53 codon 72 polymorphism in ...
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Association between p53 Codon 72 (Arg72Pro) Polymorphism and Primary Open-Angle Glaucoma in Iranian Patients
... of p53 at codon 72, either encoding proline or arginine, has known as a genetic factor associated with clinical outcome or several different neoplasms in humans, such as lung cancer, colorectal ...
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P53 CODON 72 POLYMORPHISM AND HUMAN PAPILLOMAVIRUS ASSOCIATED SKIN CANCER
... the p53 codon 72 genotype, and the development of cutaneous carcinomas in both renal transplant recipients and in immunocompetent patients with skin ...of p53 after renal ...
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A preliminary study of microsatellite instability analysis in different genotypes of p53 codon 72 in breast invasive ductal carcinomas
... the p53 codon 72 variation and presence of MSI in the invasive breast duc- tal ...between p53 and the MMR system and indicated that heterozygosity for p53 codon 72 may ...
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Detection of human papillomavirus DNA and p53 codon 72 polymorphism in prostate carcinomas of patients from Argentina
... the p53 codon 72 pol- ymorphism have been performed after the initial report claiming a higher cancer risk associated with the Arg allele ...the p53 polymorphism at codon 72, we ...
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Effect of p53 Codon 72 Polymorphism on Clinical Outcome in Locally Advanced Breast Cancer Patients Receiving Anthracycline Based Neoadjuvant Chemotherapy
... of p53 72G>A variant were not significant between responders and non-responders and also in dominant and recessive genetic model (Table ...of p53 72G>A variant were significantly different between ...
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Genotyping of P53 Gene Exon 4 Codon 72 in Sudanese Patients with Myelogenous Leukaemias
... 4, codon 72 Arginine (Arg)/Proline (Pro) polymorphism has been reported to be associated with the risk of many types of ...of P53 codon 72 Arg/Pro polymorphism and the risk of ...
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... gene p53 codon 72 is obtained through DNA extraction process and PCR-RFLP method from blood ...gene p53 codon 72 is recognized with BstUI ...
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P53 codon 11, 72, and 248 gene polymorphisms in endometriosis
... The primer Pro72 was designed for p53 codon 72 in proline (Pro) form and Arg72 for arginine (Arg) form, according to the procedure described by Storey et al. [4]. P53codon 11 and 248 gene ...
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TP53 codon 72 polymorphism may predict early tumour progression in paediatric pilocytic astrocytoma
... IR of death or disease progression were calculated and reported with their 95% Confidence Intervals (95% CI). Survival curves were drawn to assess disease-free survival and time to the event was expressed as person- ...
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Molecular epidemiology of Human Papillomaviruses in breast cancer, Golestan province of Iran
... Detection of human papillomavirus DNA in breast cancer of patients with cervical cancer history.. p53 codon 72 polymorphism (C/G) and the risk of human papillomavirus-associated carci[r] ...
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Analysis of p53 gene polymorphism (codon 72) in symptomatic patients with atherosclerosis.
... The p53 codon 72 of exon 4 shows a polymorphism characterized by a substitution of guanine (G) by a cytosine (C), which determines the alteration of the amino acid arginine to proline in the ...of ...
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Assessment of changes in the brca2 and p53 genes in breast invasive ductal carcinoma in northeast Brazil
... tween p53 codon 72 genotype and clinical pathologic data is summarized in Tables 1 and ...2. p53 codon 249 analysis has shown no statistic significance with any pa- rameters chosen in ...
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MDM2 SNP309 (rs2279744) and p53 Codon Arg72Pro (rs1042522) SNP in Cervical Carcinogenesis
... the p53 and murine double minute 2 homolog (MDM2) promoter 309 in cervical ...at p53 codon 72 poly- morphisms and MDM2 promoter 309 (T/G) together with human papillomavirus (HPV) types were ...
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RESEARCH ARTICLE Association of TP53 codon 72 polymorphism in women suffering from endometriosis from Lahore, Pakistan
... of p53 codon 72 polymorphism was checked in overall study subjects and then in controls and cases for deviation from Hardy-Weinberg equilibrium (HWE) using Online Encyclopaedia for Genetic ...
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... The common p53 polymorphisms include codon 72 (c.215C>G; p.R72P), deletion of 16bp in intron 3 (c.96+41_96+56del16) and c.672+62A>G polymorphisms [12]. While the two SNPs were only detected the ...
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Polymorphisms of TP53 codon 72 with breast carcinoma risk: evidence from 12226 cases and 10782 controls
... Recently, a growing body of research has conducted on the association of breast cancer risk with tumour suppres- sors. TP53, one of the most extensive studied genes as a tumor suppressor, has been thought to have a ...
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TP 53 and MDM2 gene polymorphisms and risk of hepatocellular carcinoma among Italian patients
... to develop liver cancer (OR, 2.304; 95% CI, 1.014-5.234) was observed among Moroccan subjects [30]. The analy- sis of pooled data from six case-control studies includ- ing 836 and 279 liver cancer and 1’191 and 587 ...
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